Hepatitis C
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Racial Difference in HCV/Host Interactions
An NIAID-funded clinical trial examining racial differences in host interactions with hepatitis C virus has completed. The update discusses …
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Effectiveness of Paritaprevir/Ritonavir, Ombitasvir, + Dasabuvir, ± Ribavirin in Patients With Chronic Hepatitis C in Romania
A completed clinical trial in Romania evaluated the effectiveness of the hepatitis C regimen Paritaprevir/ritonavir/ombitasvir plus dasabuvi…
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CLINICAL_TRIALS withdrawal · 2019-01-23Clinical Trial Update: TG4040 in Patients With Chronic HCV [Phase 1]
A Phase 1 clinical trial of TG4040 for chronic Hepatitis C has been withdrawn.
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CLINICAL_TRIALS research · 2019-01-23Clinical Trial Update: Hepatitis C Patient Management and Family Health Education [NA]
This clinical trial update relates to Hepatitis C patient management and family health education, sponsored by China Liver Health; the curre…
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CLINICAL_TRIALS trial_result · 2019-01-22Clinical Trial Update: Efficacy and Safety of Combinations of AL-335, Odalasvir (ODV) and Simeprevir (SMV) in the Treatment of Chronic Hepatitis C Infection [Phase 2]
Phase 2 trial update on combinations of AL-335, Odalasvir and Simeprevir for chronic hepatitis C; results posted after completion.
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CLINICAL_TRIALS trial_result · 2019-01-09Clinical Trial Update: Daclatasvir, Asunaprevir Plus Ribavirin for HCV Genotype 1b Without NS5A RAV [Phase 3]
Phase 3 trial update on daclatasvir, asunaprevir plus ribavirin for hepatitis C genotype 1b without NS5A resistance-associated variants has …
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CLINICAL_TRIALS trial_result · 2019-01-09Clinical Trial Update: 8 Weeks Versus 12 Weeks of Elbasvir/Grazoprevir in Treatment-naïve CHC With Mild Fibrosis [Phase 3]
Phase 3 trial comparing 8 weeks vs 12 weeks of elbasvir/grazoprevir in treatment-naïve chronic hepatitis C with mild fibrosis completed.
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CLINICAL_TRIALS trial_result · 2019-01-08Clinical Trial Update: Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Participants With Chronic HCV [Phase 3]
Phase 3 trial evaluating sofobuvir/velpatasvir fixed-dose combination over 12 weeks for chronic hepatitis C shows efficacy and safety result…
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CLINICAL_TRIALS trial_result · 2018-12-31Clinical Trial Update: Effectiveness of Paritaprevir/r - Ombitasvir, ± Dasabuvir, ± Ribavirin in Patients With Chronic Hepatitis C - An Observational Study
An observational study assessing the effectiveness of paritaprevir/ritonavir-ombitasvir ± dasabuvir ± ribavirin in patients with chronic hep…
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CLINICAL_TRIALS trial_result · 2018-12-31Clinical Trial Update: Evaluation of MK-1075 in Participants With Hepatitis C Virus (HCV) Infection (MK-1075-002) [Phase 1]
This publication reports results from a Phase 1 study evaluating MK-1075 in participants with hepatitis C virus infection.
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CLINICAL_TRIALS trial_result · 2018-12-28Clinical Trial Update: Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Participants With Chronic Genotype 1 HCV Infection [Phase 3]
Phase 3 trial update showing efficacy and safety of the ledipasvir/sofosbuvir fixed-dose combination in chronic genotype 1 hepatitis C infec…
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CLINICAL_TRIALS trial_result · 2018-12-26Clinical Trial Update: Efficacy and Safety of Uprifosbuvir (MK-3682) + Ruzasvir (MK-8408) in Treating Hepatitis C Virus Infection Genotypes 1-6 (MK-3682-041) [Phase 2]
Phase 2 trial evaluating Uprifosbuvir + Ruzasvir for hepatitis C genotypes 1-6; study terminated with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-12-20Clinical Trial Update: Efficacy and Tolerability of Grazoprevir and Elbasvir in Patients With Chronic Genotype 1 HCV and HIV Co-infection [Phase 4]
A Phase 4 trial updated on the efficacy and tolerability of grazoprevir and elbasvir in patients with chronic hepatitis C and HIV co-infecti…
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CLINICAL_TRIALS withdrawal · 2018-12-20Clinical Trial Update: Direct-acting Antiviral Therapy to Prevent HCV Infection for HCV Positive Donor to HCV Negative Recipient Kidney Transplant [Phase 4]
A Phase 4 trial evaluating direct-acting antiviral therapy to prevent HCV infection in HCV-positive donor to HCV-negative recipient kidney t…
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CLINICAL_TRIALS withdrawal · 2018-12-20Clinical Trial Update: Preemptive Zepatier Treatment in Donor HCV Positive to Recipient HCV Negative Cardiac Transplant [Phase 4]
Clinical trial on preemptive Zepatier treatment in HCV-positive donors to HCV-negative recipients in cardiac transplant was withdrawn (Phase…
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: Efficacy and Safety of All-Oral Combination of Narlaprevir/Ritonavir and Daclatasvir in Treatment-Naїve Patients With Chronic Hepatitis C Genotype 1b [Phase 2]
Phase 2 clinical trial evaluating an all-oral combination of Narlaprevir/Ritonavir and Daclatasvir for treatment-naïve patients with chronic…
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CLINICAL_TRIALS research · 2018-12-14Clinical Trial Update: Pharmacokinetics of MK-3682B in Participants With Moderate to Severe Renal Insufficiency (MK-3682B-030) [Phase 1]
Phase 1 pharmacokinetics study of MK-3682B in participants with moderate to severe renal impairment for hepatitis C has completed with resul…
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CLINICAL_TRIALS trial_result · 2018-12-11Clinical Trial Update: Portal-724 MEMS for Medication Adherence Patients Taking HCV Medications
Clinical trial update for Portal-724 MEMS aimed at improving adherence to hepatitis C medications; study completed with results posted in 20…
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CLINICAL_TRIALS trial_result · 2018-11-28Clinical Trial Update: Safety, Pharmacokinetics, and Pharmacodynamics of Ruzasvir (MK-8408) in Participants With Hepatitis C Infection (MK-8408-003) [Phase 1]
Phase 1 clinical trial update on safety, pharmacokinetics, and pharmacodynamics of ruzasvir (MK-8408) in participants with hepatitis C infec…
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CLINICAL_TRIALS trial_result · 2018-11-21Clinical Trial Update: A Study of Pharmacokinetics, Efficacy, Safety, Tolerability, of the Combination of Simeprevir (TMC435), Daclatasvir (BMS-790052), and Ribavirin (RBV) in Patients With Recurrent Chronic Hepatitis C Genotype 1b Infection After Orthotopic Liver Transplantation [Phase 2]
Phase 2 trial assessing pharmacokinetics, efficacy, safety, and tolerability of a combination therapy (simeprevir, daclatasvir, ribavirin) i…
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CLINICAL_TRIALS research · 2018-11-20Clinical Trial Update: Hepatitis C Testing in VA Community-Based Outpatient Clinics [NA]
A completed clinical trial investigating hepatitis C testing in VA community-based outpatient clinics; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-11-16Clinical Trial Update: Treatment of Egyptian Hepatitis C Genotype 4 Infected Children and Adolescents With Combined Ledipasvir/Sofosbuvir [Phase 4]
Phase 4 study evaluating ledipasvir/sofosbuvir in children and adolescents with Hepatitis C Genotype 4.
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CLINICAL_TRIALS research · 2018-11-14Clinical Trial Update: Observational, Multi-Center Study of the Real World Evidence of the Effectiveness of Paritaprevir/r - Ombitasvir, ± Dasabuvir, ± Ribavirin in Patients With Chronic Hepatitis C in the Russian Federation
Observational real-world study of the effectiveness of Paritaprevir/ritonavir, Ombitasvir, with or without Dasabuvir and Ribavirin in chroni…
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CLINICAL_TRIALS trial_result · 2018-11-13Clinical Trial Update: A Multiple-Dose Study to Evaluate MK-1075 in Hepatitis C Virus (HCV) Infected Participants (MK-1075-004) [Phase 1]
Phase 1 multiple-dose study assessing MK-1075 in participants infected with hepatitis C virus has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-11-05Clinical Trial Update: Increasing Cure Rate of Hepatitis C Therapy in Obese Hepatitis C Patients [NA]
Clinical trial update on hepatitis C therapy in obese patients; status terminated with results posted in 2018.