Hepatitis C
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Sign up freeTop drugs studied for this disease
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FDA approval · 2020-04-10FDA Approved: MAVYRET — Supplemental Application (AbbVie Inc.)
The FDA approved a supplemental application for MAVYRET (glecaprevir and pibrentasvir) from AbbVie.
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CLINICAL_TRIALS trial_result · 2020-03-20Clinical Trial Update: Efficacy Study of Mirtazapine to Treat Interferon-related Depression During Antiviral Therapy for Hepatitis C [Phase 4]
Phase 4 trial updating efficacy of mirtazapine for interferon-related depression during antiviral therapy for hepatitis C; the study is term…
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CLINICAL_TRIALS trial_result · 2020-03-20Clinical Trial Update: Pharmacokinetics of Voxilaprevir in Adults With Normal Hepatic Function and Moderate or Severe Hepatic Impairment [Phase 1]
Phase 1 pharmacokinetics study of voxilaprevir in adults with varying hepatic function completed.
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CLINICAL_TRIALS trial_result · 2020-03-20Clinical Trial Update: Pharmacokinetics of Voxilaprevir in Adults With Normal Renal Function and Severe Renal Impairment [Phase 1]
Phase 1 pharmacokinetics study of Voxilaprevir in adults with normal renal function and severe renal impairment; results completed and poste…
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FDA approval · 2020-03-19FDA Approved: EPCLUSA — Supplemental Application (Gilead Sciences, Inc.)
FDA approved a supplemental application for EPCLUSA (velpatasvir/sofosbuvir) from Gilead Sciences.
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CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected With Different Hepatitis C Virus Genotypes During Therapy With Sofosbuvir and GS-5816 [Phase 2]
Phase 2 clinical trial update on viral kinetics, ISGs, and mirRNA in Chronic Hepatitis C patients treated with sofosbuvir and GS-5816; resul…
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CLINICAL_TRIALS trial_result · 2020-03-18Clinical Trial Update: Phase 3 Study of Yimitasvir Phosphate Capsules [Phase 3]
Phase 3 study completed for Yimitasvir Phosphate Capsules in chronic hepatitis C virus infection.
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CLINICAL_TRIALS trial_result · 2020-03-18Clinical Trial Update: Phase 2 Study of Yimitasvir Phosphate Capsules [Phase 2]
Phase 2 study of Yimitasvir Phosphate Capsules for chronic hepatitis C has completed.
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CLINICAL_TRIALS trial_result · 2020-03-17Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment-Naive Adults in Brazil With Chronic Hepatitis C Virus (HCV) Genotype 1 - 6 Infection [Phase 3]
Phase 3 trial evaluating glecaprevir/pibrentasvir in treatment-naive adults with chronic HCV genotypes 1-6 in Brazil completed with posted r…
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: EBR/GZR for HCV-1b Patients Receiving Hemodialysis [Phase 4]
Phase 4 trial update of EBR/GZR in Hepatitis C patients on hemodialysis has completed with posted results.
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FDA approval · 2020-03-05FDA Approved: LEDIPASVIR AND SOFOSBUVIR — Supplemental Application (Asegua Therapeutics LLC)
The FDA approved a supplemental application for Ledipasvir and Sofosbuvir submitted by Asegua Therapeutics LLC.
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FDA approval · 2020-03-05FDA Approved: SOVALDI — Supplemental Application (Gilead Sciences, Inc.)
FDA approved a supplemental application for Sovaldi (sofosbuvir) submitted by Gilead Sciences, Inc.
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CLINICAL_TRIALS trial_result · 2020-03-04Clinical Trial Update: Effects of Persistent Innate Immune Activation on Vaccine Efficacy [Phase 4]
Phase 4 trial investigating how persistent innate immune activation affects vaccine efficacy, terminated with results posted.
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CLINICAL_TRIALS withdrawal · 2020-02-26Clinical Trial Update: A Prospective Cohort Study to Improve HCV Care in Dialysis Patients [Phase 4]
Phase 4 prospective cohort study to improve hepatitis C care in dialysis patients was withdrawn.
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CLINICAL_TRIALS trial_result · 2020-02-13Clinical Trial Update: Safety and Efficacy of Grazoprevir and Elbasvir for GT1ang GT6 With and Without HIV [Phase 4]
Phase 4 trial update on the safety and efficacy of grazoprevir and elbasvir for genotype 1 and genotype 6 hepatitis C, with and without HIV,…
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CLINICAL_TRIALS trial_result · 2020-02-12Clinical Trial Update: Prevalence of Kidney Injury in Patients With HCV Treated With Sofuspovir Containing DAA Therapy [Phase 4]
Phase 4 trial update assessing prevalence of kidney injury in patients with hepatitis C treated with sofusbuvir-containing direct-acting ant…
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: 'Fibrosis in the Lost Hepatitis C Population - Track, Trace and Treat'
A completed clinical trial (NCT03088917) conducted by Radboud University Medical Center investigating fibrosis in chronic hepatitis C patien…
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: Multi-Center, Randomized, Open-Label Study of G/P +/- RBV for NS5A + SOF Previously Treated GT1 HCV Subjects [Phase 3]
Phase 3 trial update for G/P +/- RBV in previously treated genotype 1 hepatitis C patients completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-01-29Clinical Trial Update: Short Duration Therapy of Acute Hepatitis C Genotypes 1 or 4 [Phase 2]
Phase 2 trial evaluating short-duration therapy for acute hepatitis C genotypes 1 or 4; results posted after completion.
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CLINICAL_TRIALS trial_result · 2020-01-28Clinical Trial Update: Expression of Inflammasomes in HCV Patients [Phase 4]
Phase 4 clinical trial investigating expression of inflammasomes in patients with Hepatitis C.
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CLINICAL_TRIALS withdrawal · 2020-01-21Clinical Trial Update: HCV Post-Exposure Prophylaxis for Health Care Workers [Phase 4]
A Phase 4 clinical trial studying Hepatitis C post-exposure prophylaxis for healthcare workers was withdrawn.
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CLINICAL_TRIALS trial_result · 2020-01-10Clinical Trial Update: Ombitasvir/ Paritaprevir / Ritonavir Plus Ribavirin in Management HCV and End-stage Kidney Disease [Phase 4]
Phase 4 trial update evaluating Ombitasvir/Paritaprevir/Ritonavir plus Ribavirin for management of hepatitis C in patients with end-stage ki…
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CLINICAL_TRIALS trial_result · 2020-01-09Clinical Trial Update: Effect of Harvoni on Proteinuria and eGFR in Hepatitis C Virus Associated Chronic Kidney Disease (CKD) [NA]
A terminated clinical trial assessing the effect of Harvoni on proteinuria and eGFR in patients with hepatitis C–associated chronic kidney d…
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CLINICAL_TRIALS trial_result · 2019-12-30Clinical Trial Update: Scale-up of Treatment of Hepatitis C Infection Among People Who Inject Drugs [Phase 4]
A Phase 4 trial update on scaling up Hepatitis C treatment among people who inject drugs; the study is terminated with results posted in 201…
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CLINICAL_TRIALS trial_result · 2019-12-24Clinical Trial Update: Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy [Phase 4]
Phase 4 clinical trial evaluating switching to Genvoya, followed by HCV therapy with Epclusa, and subsequent simplification to Biktarvy in H…