Hepatitis C
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CLINICAL_TRIALS research · 2023-08-22Clinical Trial Update: Pharmacokinetics of Ledipasvir/Sofosbuvir in Hepatitis C Virus-Infected Children With Hematological Malignancy [Phase 1, Phase 2]
A phased pharmacokinetic study of the Ledipasvir/Sofosbuvir combination in children with chronic hepatitis C and concurrent hematologic mali…
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: MHH-HCV-NPM-Neuropsychiatric Manifestations of HCV-infection During and After Treatment With OBV/PTV/r and DSV [Phase 4]
Phase 4 trial update investigating neuropsychiatric manifestations of chronic hepatitis C during and after treatment with OBV/PTV/r and DSV;…
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Safety And Efficacy Of Oral PF-4136309 In Patients With Chronic Hepatitis C Infection And Abnormal Liver Enzymes [Phase 2]
Phase 2 trial updating safety and efficacy results for oral PF-4136309 in patients with chronic hepatitis C and abnormal liver enzymes; stud…
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CLINICAL_TRIALS trial_result · 2023-07-06Clinical Trial Update: Prolonged Release Pirfenidone for Advanced Residual Liver Fibrosis (MINERVA). [Phase 2]
Phase 2 trial update for prolonged-release pirfenidone in advanced residual liver fibrosis due to liver cirrhosis and chronic hepatitis C.
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Harvoni Treatment Porphyria Cutanea Tarda [Phase 2]
Phase 2 clinical trial updating Harvoni treatment for Porphyria Cutanea Tarda and Hepatitis C has completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-06-13Clinical Trial Update: Efficacy and Safety Study of Pegylated Interferon Lambda-1a With Ribavirin and Daclatasvir, to Treat naïve Subjects With Chronic HCV Genotypes 1, 2, 3, and 4 Who Are Co-infected With HIV [Phase 3]
Phase 3 study evaluating pegylated interferon lambda-1a with ribavirin and daclatasvir for chronic hepatitis C in treatment-naïve patients c…
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: Treatment of HCV-Infected Recent Injection Drug Users in U.S. Liver Clinics [Phase 4]
Phase 4 clinical trial update on treating chronic hepatitis C in people who inject drugs in U.S. liver clinics.
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CLINICAL_TRIALS trial_result · 2023-05-22Clinical Trial Update: Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes After Hepatitis C Eradication [Phase 4]
Phase 4 trial updating cardiovascular risk outcomes after hepatitis C eradication in individuals with HIV and hepatitis C; results posted.
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CLINICAL_TRIALS trial_result · 2023-05-11Clinical Trial Update: Pharmacokinetics, Safety, Efficacy and Acceptability of Daclatasvir Plus Sofosbuvir in HCV-infected Children [Phase 3]
Phase 3 clinical trial update evaluating daclatasvir plus sofosbuvir in children with hepatitis C virus infection, focusing on pharmacokinet…
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: Sofosbuvir/Velpatasvir in Postpartum Women With Opioid Use Disorder and Chronic Hepatitis C Infection [Phase 4]
Phase 4 clinical trial update for Sofosbuvir/Velpatasvir in postpartum women with opioid use disorder and chronic hepatitis C infection; stu…
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: ATTIC - Access To Treat in the Community [Phase 4]
Phase 4 clinical trial ATTIC (Access To Treat in the Community) for chronic hepatitis C has been terminated.
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CLINICAL_TRIALS trial_result · 2023-04-25Clinical Trial Update: Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Lung Transplant [Phase 4]
Phase 4 clinical trial evaluating pan-genotypic direct-acting antiviral therapy in donor HCV-positive to recipient HCV-negative lung transpl…
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CLINICAL_TRIALS trial_result · 2023-04-20Clinical Trial Update: Sofosbuvir, Daclatasvir, Ribavirin for Hepatitis C Virus (HCV) Cirrhotics [Phase 3]
Phase 3 trial evaluating sofosbuvir, daclatasvir, and ribavirin in hepatitis C patients with cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2023-04-07Clinical Trial Update: A Study to Evaluate Long-term Outcomes Following Treatment With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection [Phase 3]
A Phase 3 trial evaluating long-term outcomes of ABT-450/r/ABT-267 with or without ABT-333 and ribavirin in adults with genotype 1 chronic h…
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: HCV Related Hepatocellular Carcinoma Recurrence After Directly Acting Antivirals: A Randomized Controlled Trial [Phase 4]
Phase 4 randomized trial evaluating recurrence after direct-acting antivirals in hepatitis C-related hepatocellular carcinoma; study complet…
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CLINICAL_TRIALS trial_result · 2023-03-31Clinical Trial Update: Ledipasvir+Sofosbuvir and Sofosbuvir+Velpatasvir for Pts With Indolent Bcell Lymphoma Associated With HCV Infection [Phase 2]
A Phase 2 trial evaluated Ledipasvir+Sofosbuvir and Sofosbuvir+Velpatasvir in patients with indolent B-cell lymphoma associated with hepatit…
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CLINICAL_TRIALS trial_result · 2023-03-06Clinical Trial Update: PK of SOF/LED in HCV - Infected Adolescents With Haematological Disorders [Phase 3]
Phase 3 trial update evaluating the pharmacokinetics of sofosbuvir/ledipasvir in adolescents with hepatitis C infection and beta-thalassemia…
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CLINICAL_TRIALS research · 2023-03-06Clinical Trial Update: Clinical Pharmacokinetics of Daclatasvir/Sofosbuvir in Adolescents With Hepatitis C Virus [Phase 2, Phase 3]
A clinical trial update evaluating the pharmacokinetics of daclatasvir/sofosbuvir in adolescents with chronic hepatitis C virus infection ac…
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CLINICAL_TRIALS trial_result · 2023-03-06Clinical Trial Update: Add Vitamin D With Standard of Care for Chronic Hepatitis C Patients [Phase 4]
A Phase 4 clinical trial evaluated adding vitamin D to standard of care for patients with chronic hepatitis C; the study is completed.
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CLINICAL_TRIALS trial_result · 2023-02-23Clinical Trial Update: Determine the Efficacy and Safety of Harvoni in Genotype 1 Chronic Hepatitis c Infected People Who Are Alcoholics [Phase 4]
A Phase 4 trial evaluating the efficacy and safety of Harvoni (ledipasvir/sofosbuvir) in adults with Genotype 1 hepatitis C who are alcoholi…
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CLINICAL_TRIALS trial_result · 2023-02-22Clinical Trial Update: Elbasvir/Grazoprevir Fixed-Dose Combination for 8 Weeks in G1b Treatment-Naïve, HCV-Infected Patients [Phase 3]
Phase 3 trial assessing 8-week Elbasvir/Grazoprevir fixed-dose therapy in treatment-naïve genotype 1b hepatitis C patients has completed.
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CLINICAL_TRIALS research · 2023-02-22Clinical Trial Update: Accessible HCV Care Intervention for People Who Inject Illicit Drugs (PWID) [NA]
Clinical trial update on an accessible hepatitis C care intervention for people who inject drugs, with completed status and results posted.
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CLINICAL_TRIALS research · 2023-02-10Clinical Trial Update: Universal HIV Screening and Targeted HCV Screening in Emergency Department [NA]
A completed clinical trial evaluating universal HIV and targeted HCV screening in emergency departments, with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-02-08Clinical Trial Update: Effect of New Oral Treatment for Hepatitis C Virus on Seminal Parameters [Phase 2, Phase 3]
A Phase 2/3 trial evaluating a new oral treatment for hepatitis C shows effects on seminal parameters in male participants with HCV-related …
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CLINICAL_TRIALS trial_result · 2023-01-05Clinical Trial Update: Telaprevir in Genotype 3 HCV [Phase 4]
Phase 4 clinical trial update for telaprevir in genotype 3 hepatitis C (completed).