Hepatitis C
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CLINICAL_TRIALS trial_result · 2012-11-22Clinical Trial Update: A Pilot Study to Treat Patients With Chronic Hepatitis C Virus (HCV) Genotype 1 and End-Stage Renal Disease (ESRD) [Phase 4]
This report provides a Phase 4 pilot clinical trial update evaluating treatment in patients with chronic hepatitis C virus infection and end…
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CLINICAL_TRIALS trial_result · 2012-11-20Clinical Trial Update: Effective Treatment of Hepatitis C in Substance Users [NA]
This clinical trial update reports the results of treating Hepatitis C in individuals with opioid dependence; the study has completed and re…
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CLINICAL_TRIALS trial_result · 2012-11-20Clinical Trial Update: Post Marketing Observational Study of Retreatment of Chronic Hepatitis C With Peginterferon Alpha and Ribavirin (Study P06011)
This is a completed post-marketing observational study evaluating retreatment of chronic hepatitis C with peginterferon alfa and ribavirin; …
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CLINICAL_TRIALS trial_result · 2012-11-16Clinical Trial Update: A Phase 1 Study of PPI-668 in Healthy Volunteers and Patients With Hepatitis C Virus (HCV) Genotype 1 [Phase 1]
Phase 1 trial of PPI-668 in healthy volunteers and patients with chronic hepatitis C (genotype 1) has completed, evaluating safety and pharm…
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CLINICAL_TRIALS trial_result · 2012-11-15Clinical Trial Update: Boceprevir/Peginterferon/Ribavirin for Chronic Hepatitis C: Erythropoietin Use Versus Ribavirin Dose Reduction for Anemia (P06086 AM2) [Phase 3]
Phase 3 trial comparing erythropoietin use vs ribavirin dose reduction for anemia in Boceprevir/peginterferon/ribavirin treatment of chronic…
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CLINICAL_TRIALS trial_result · 2012-11-14Clinical Trial Update: Safety, Tolerability, and Antiviral Activity of ANA598 in Patients With Genotype-1 Chronic HCV Infection [Phase 1]
Phase 1 study assessing safety, tolerability, and antiviral activity of ANA598 in patients with genotype-1 chronic hepatitis C.
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CLINICAL_TRIALS trial_result · 2012-11-14Clinical Trial Update: Study of ANA773 in Healthy Volunteers and Patients With Hepatitis C Virus (HCV) to Assess Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) [Phase 1]
Phase 1 trial update for ANA773 in healthy volunteers and hepatitis C patients assessing safety, tolerability, pharmacokinetics and pharmaco…
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CLINICAL_TRIALS trial_result · 2012-11-12Clinical Trial Update: Drug Interaction Study to Assess the Effect of Co-Administered Miravirsen and Telaprevir in Healthy Subjects [Phase 1]
Phase 1 study assessed the drug interaction between Miravirsen and Telaprevir in healthy subjects; the trial has completed.
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CLINICAL_TRIALS trial_result · 2012-11-08Clinical Trial Update: TMC435-TiDP16-C123 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and the Antiretroviral Agents Efavirenz and Raltegravir [Phase 1]
A Phase 1 study in healthy volunteers assessing the pharmacokinetic interaction between the anti-HCV candidate TMC435 and antiretroviral age…
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CLINICAL_TRIALS trial_result · 2012-11-01Clinical Trial Update: A Study in Healthy Participants Investigating the Effect of TMC435 on the Pharmacokinetics of Immunosuppressants Cyclosporine and Tacrolimus [Phase 1]
A Phase 1 study in healthy participants assessed the effect of TMC435 on the pharmacokinetics of cyclosporine and tacrolimus. The trial has …
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: Observational Study Assessing Chronic Hepatitis C Management in Clinical Practice in Italy (Study P05488 AM1)
An observational study conducted in Italy evaluated real-world management of chronic hepatitis C; the study (P05488 AM1) is completed with r…
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: Safety and Efficacy Study of CENV3 Vaccine to Protect Against HCV Infection [Phase 1, Phase 2]
This document provides an update on a Phase 1/2 safety and efficacy study of the CENV3 vaccine intended to prevent hepatitis C virus infecti…
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CLINICAL_TRIALS trial_result · 2012-10-30Clinical Trial Update: Hepatitis C Treatment in Underserved Populations [NA]
A clinical trial update about hepatitis C treatment in underserved populations; the current status of the trial is unknown.
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CLINICAL_TRIALS trial_result · 2012-10-26Clinical Trial Update: TMC649128HPC1002 - a Trial inGenotype 1 Hepatitis C Virus (HCV) - Infected Participants to Determine the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of TMC649128, Alone and Combined With Pegylated Interferon + Ribavirin [Phase 1]
Phase 1 trial to assess safety, tolerability, pharmacokinetics and antiviral activity of TMC649128 alone and with pegylated interferon plus …
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CLINICAL_TRIALS trial_result · 2012-10-23Clinical Trial Update: Comparison of Pegasys Versus Peg-Intron for Treatment of Chronic Hepatitis C Genotype 4 [Phase 4]
A Phase 4 clinical trial comparing Pegasys and Peg-Intron for chronic hepatitis C genotype 4 has completed.
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CLINICAL_TRIALS trial_result · 2012-10-22Clinical Trial Update: Safety and PK Study of MP-424 to Treat Chronic Hepatitis C [Phase 1]
A Phase 1 safety and pharmacokinetics study of MP-424 for chronic hepatitis C has completed, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-10-19Clinical Trial Update: Phase II Study of Immunization With a Hepatitis C Virus (HCV) Antigen Peptide Vaccine [Phase 2]
A Phase II clinical trial evaluating an HCV antigen peptide vaccine for chronic hepatitis C has completed.
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CLINICAL_TRIALS trial_result · 2012-10-19Clinical Trial Update: Safety and Efficacy of MP-424 to Treat Chronic Hepatitis C [Phase 2]
Phase 2 trial results evaluating MP-424 for chronic hepatitis C, reporting safety and efficacy outcomes.
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CLINICAL_TRIALS trial_result · 2012-10-18Clinical Trial Update: Dose Escalation Study of IL-7 and Bi-therapy in HCV Patients Resistant After 12 Weeks of Bi-therapy (ECLIPSE 1) [Phase 1, Phase 2]
A completed dose-escalation study evaluated the safety and preliminary efficacy of interleukin-7 in combination with Bi-therapy in Hepatitis…
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CLINICAL_TRIALS trial_result · 2012-10-18Clinical Trial Update: Dose Escalation Study of Interleukin-7 (IL-7) and Bitherapy in HCV Genotype 1 or 4 Patients Resistant to Bitherapy Alone [Phase 1, Phase 2]
Phase 1/2 dose-escalation trial evaluating Interleukin-7 in combination with Bitherapy in Hepatitis C patients who are resistant to Bitherap…
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CLINICAL_TRIALS trial_result · 2012-10-17Clinical Trial Update: Keyhole Limpet Hemocyanin in Chronic Hepatitis C [NA]
A completed clinical trial investigating Keyhole Limpet Hemocyanin in patients with chronic hepatitis C and liver cirrhosis.
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CLINICAL_TRIALS trial_result · 2012-10-16Clinical Trial Update: VX-950HEP1001 - Drug-drug Interaction Study Between Telaprevir and Raltegravir [Phase 1]
This document reports the completion of a Phase 1 drug-drug interaction study evaluating the combination of telaprevir and raltegravir for H…
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CLINICAL_TRIALS trial_result · 2012-10-15Clinical Trial Update: Infergen and Ribavirin Treatment of Patients With HCV Who Achieved Partial Response to Peginterferon-alfa and Ribavirin [Phase 4]
Phase 4 trial evaluating Infergen (interferon alfacon-1) plus ribavirin in hepatitis C patients who partially responded to peginterferon-alf…
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CLINICAL_TRIALS trial_result · 2012-10-11Clinical Trial Update: TMC435-TiDP16-C115 - A Study in Healthy Volunteers Investigating the Pharmacokinetic Interaction Between TMC435 and Erythromycin and Between TMC435 and Darunavir/Ritonavir (DRV/r) [Phase 1]
Phase 1 PK interaction study in healthy volunteers to evaluate how TMC435 interacts with erythromycin and with darunavir/ritonavir, in the H…
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CLINICAL_TRIALS trial_result · 2012-10-11Clinical Trial Update: TMC435-TiDP16-C116 - Relative Bioavailability and Food Effect Study [Phase 1]
Phase 1 trial update for TMC435-TiDP16-C116 assessing relative bioavailability and the effect of food in Hepatitis C patients; study status …