Hepatitis C

• CLINICAL_TRIALS trial_result · 2014-10-09
  Clinical Trial Update: Sofosbuvir and Ribavirin in Treatment-Naive and Treatment-Experienced Subjects With Chronic Genotype 2 or 3 HCV Infection [Phase 3]

  Phase 3 results of the combination of sofosbuvir and ribavirin in treatment-naive and treatment-experienced adults with chronic hepatitis C …

• CLINICAL_TRIALS trial_result · 2014-10-08
  Clinical Trial Update: Pharmacokinetics of Boceprevir in Pediatric Subjects With Chronic Hepatitis C Genotype 1 (P07614) [Phase 1]

  Phase 1 pharmacokinetics study of boceprevir in pediatric patients with chronic hepatitis C genotype 1; study terminated with results posted…

• CLINICAL_TRIALS trial_result · 2014-10-07
  Clinical Trial Update: Efficacy and Safety Study of Peginterferon Alfa-2b in Chinese Chronic Hepatitis C Patients [Phase 3]

  A Phase 3 trial evaluating peginterferon alfa-2b for chronic hepatitis C in Chinese patients has completed, examining efficacy and safety ou…

• CLINICAL_TRIALS trial_result · 2014-10-06
  Clinical Trial Update: Vaniprevir Administered With Pegylated-interferon and Ribavirin in Japanese Treatment-Naïve Chronic Hepatitis C Participants (MK-7009-043) [Phase 3]

  Phase 3 trial update of vaniprevir with pegylated interferon and ribavirin in treatment-naïve Japanese patients with chronic hepatitis C, wi…

• CLINICAL_TRIALS trial_result · 2014-10-03
  Clinical Trial Update: Evaluation of Safety, Tolerability, and Antiviral Activity of ACH-0143102 Plus Ribavirin In Treatment-naive Hepatitis C Virus Infection Genotype 1b Participants [Phase 1]

  Phase 1 clinical trial evaluating ACH-0143102 plus ribavirin for safety, tolerability, and antiviral activity in treatment-naive genotype 1b…

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• CLINICAL_TRIALS trial_result · 2014-10-02
  Clinical Trial Update: Evaluation of the Antiviral Pharmacodynamic Effect, Safety, and Pharmacokinetics of Escalating Doses of BILB 1941 ZW to Patients With Chronic Hepatitis C Genotype 1 Virus Infection [Phase 1, Phase 2]

  Phase 1/2 clinical trial in chronic hepatitis C evaluated antiviral pharmacodynamics, safety, and pharmacokinetics of escalating doses of BI…

• CLINICAL_TRIALS trial_result · 2014-10-02
  Clinical Trial Update: Open Label Study to Evaluate Chronic Hepatitis C Treatment in Latino Subjects With and Without HIV Co-infection

  Open-label study assessing chronic hepatitis C treatment in Latino patients with and without HIV co-infection; study terminated with results…

• CLINICAL_TRIALS trial_result · 2014-10-01
  Clinical Trial Update: Peginterferon Alpha-2b And Ribavirin to Treat Hepatitis C in HIV-Infected Patients [Phase 2]

  A Phase 2 trial evaluating peginterferon alfa-2b plus ribavirin for treating hepatitis C in HIV-infected patients is completed, with results…

• CLINICAL_TRIALS trial_result · 2014-10-01
  Clinical Trial Update: Safety and Efficacy of Vaniprevir (MK7009) Administered With Pegylated-Interferon and Ribavirin (MK-7009-007) [Phase 2]

  Phase 2 trial update for vaniprevir (MK7009) with peginterferon and ribavirin in Hepatitis C; results posted after completion.

• CLINICAL_TRIALS trial_result · 2014-10-01
  Clinical Trial Update: Part A: Drug Interaction Study of Sofosbuvir and Antiretroviral Therapy (ART) Combinations in HIV and Hepatitis C Virus (HCV) Co-infected Patients. Part B: Efficacy and Safety of Sofosbuvir for 12 Weeks in HIV/HCV Co-infected Patients. [Phase 1, Phase 2]

  This clinical trial update reports Part A on drug interaction between sofosbuvir and antiretroviral therapy in HIV/HCV co-infected patients,…

• CLINICAL_TRIALS trial_result · 2014-10-01
  Clinical Trial Update: Australian Trial in Acute Hepatitis C Recall Study

  Australian trial investigating Acute Hepatitis C sponsored by the Kirby Institute has completed.

• CLINICAL_TRIALS trial_result · 2014-09-30
  Clinical Trial Update: Study of the Impact of Nitazoxanide on Chronic Hepatitis Patients [Phase 2, Phase 3]

  Update on a phase 2/3 trial evaluating nitazoxanide in chronic Hepatitis C patients; the study has completed.

• CLINICAL_TRIALS trial_result · 2014-09-29
  Clinical Trial Update: A Study of Safety and Efficacy of Vaniprevir Administered With Pegylated-Interferon and Ribavirin in Japanese Participants With Chronic Hepatitis C Infection (7009-016) [Phase 2]

  Phase 2 trial assessing safety and efficacy of vaniprevir with pegylated interferon and ribavirin in Japanese participants with chronic hepa…

• CLINICAL_TRIALS trial_result · 2014-09-29
  Clinical Trial Update: Boceprevir and Ucalm (St John&Apos;s Wort) [Phase 1]

  Phase 1 trial evaluating safety and potential drug interaction between Boceprevir and St John's Wort (Ucalm) in Hepatitis C; results posted …

• CLINICAL_TRIALS trial_result · 2014-09-29
  Clinical Trial Update: A Study of Vaniprevir (MK-7009) in Participants With Chronic Hepatitis C Infection After Participation in Other Vaniprevir Studies (MK-7009-028) [Phase 2]

  Phase 2 trial update for vaniprevir (MK-7009) in chronic hepatitis C patients who previously participated in other vaniprevir studies; study…

• CLINICAL_TRIALS trial_result · 2014-09-29
  Clinical Trial Update: Pharmacokinetics of Vaniprevir (MK-7009) and Hepatitis C Virus RNA Levels After Vaniprevir Treatment (MK-7009-029) [Phase 1]

  Phase 1 pharmacokinetics and antiviral RNA data for vaniprevir (MK-7009) in chronic hepatitis C infection; study terminated with results pos…

• CLINICAL_TRIALS trial_result · 2014-09-29
  Clinical Trial Update: A Study Investigating the Influence of Hepatic Insufficiency on the Pharmacokinetics of Vaniprevir (MK-7009-005) [Phase 1]

  Phase 1 study assessing how hepatic insufficiency affects the pharmacokinetics of vaniprevir (MK-7009-005) in Hepatitis C patients; results …

• CLINICAL_TRIALS trial_result · 2014-09-29
  Clinical Trial Update: Safety and Efficacy of Vaniprevir (MK-7009) With Pegylated Interferon (Peg-IFN) and Ribavirin (RBV) in Treatment-Experienced Hepatitis C Virus (HCV) Participants (MK-7009-009) [Phase 2]

  Phase 2 trial update evaluating safety and efficacy of vaniprevir (MK-7009) with pegylated interferon and ribavirin in treatment-experienced…

• CLINICAL_TRIALS trial_result · 2014-09-29
  Clinical Trial Update: Evaluating Fine Needle Aspiration to Measure Hepatic Vaniprevir (MK-7009) Concentrations in Participants With Chronic Hepatitis C (MK-7009-048) [Phase 1]

  Phase 1 trial update evaluating fine needle aspiration to measure hepatic concentrations of vaniprevir (MK-7009) in participants with chroni…

• CLINICAL_TRIALS trial_result · 2014-09-26
  Clinical Trial Update: GS-7977 With Ribavirin for Hepatitis C (SPARE) [Phase 1, Phase 2]

  Phase 1/2 SPARE trial evaluating sofosbuvir with ribavirin for Hepatitis C completed, with results posted in September 2014.

• CLINICAL_TRIALS trial_result · 2014-09-25
  Clinical Trial Update: Hepatitis C Self-Management [NA]

  A completed VA-sponsored clinical trial on self-management for Hepatitis C has posted results in 2014.

• CLINICAL_TRIALS trial_result · 2014-09-22
  Clinical Trial Update: Randomized Controlled Trial in Liver Transplant Recipients Treated in Steroid Sparing Regimen [Phase 1]

  A Phase 1 randomized trial in liver transplant recipients evaluating a steroid-sparing immunosuppressive regimen has been completed.

• CLINICAL_TRIALS trial_result · 2014-09-17
  Clinical Trial Update: Outcomes in Hepatitis C After Living Donor Liver Transplantation in Association With Interleukin 28 B

  A completed clinical trial examining outcomes of hepatitis C after living donor liver transplantation in relation to IL28B genotype.

• CLINICAL_TRIALS trial_result · 2014-09-17
  Clinical Trial Update: Association Between Hepatitis C Infection and Renal Cell Carcinoma

  A completed clinical trial update examining the association between hepatitis C infection and renal cell carcinoma, with colorectal cancer a…

• CLINICAL_TRIALS trial_result · 2014-09-16
  Clinical Trial Update: High-Dose Ribavirin and Peginterferon to Treat Chronic Hepatitis C Genotype 1 [Phase 2]

  Phase 2 clinical trial assessing high-dose ribavirin with peginterferon for chronic hepatitis C genotype 1; the study completed and results …