Hepatitis C
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Hepatitis C Virus (HCV) Treatment Completion or Withdrawal
The document reports the completion or withdrawal of a Hepatitis C treatment study (NCT00674492); results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Open-Label Safety Study of Telaprevir and Sofosbuvir in Chronic Hepatitis C Genotype 1 [Phase 2]
An open-label Phase 2 safety study evaluating the combination of telaprevir and sofosbuvir in adults with chronic hepatitis C genotype 1; re…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Telaprevir Plus Standard of Care (SOC) in HCV Associated Hepatocellular Carcinoma (HCC) [Phase 3]
Phase 3 trial update of telaprevir with standard of care in hepatitis C virus-associated hepatocellular carcinoma has been terminated; resul…
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: THISTLE - The HIV-HCV Silibinin Trial [Phase 2]
Update on a Phase 2 HIV and Hepatitis C trial evaluating silibinin (THISTLE) conducted by University of Zurich. The trial has completed.
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CLINICAL_TRIALS trial_result · 2015-03-05Clinical Trial Update: Effect of LEGALON SIL on Hepatitis C Virus Recurrence in Stable Liver Transplanted Patients [Phase 2]
Phase 2 trial evaluating LEGALON SIL for preventing Hepatitis C recurrence in stable liver transplant recipients was terminated.
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CLINICAL_TRIALS trial_result · 2015-02-24Clinical Trial Update: A Bioequivalence Study of Daclatasvir Tablets and Bioavailability Studies of Daclatasvir and Asunaprevir [Phase 1]
This document reports a Phase 1 bioequivalence study of daclatasvir tablets and bioavailability studies of daclatasvir and asunaprevir. The …
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Japanese Phase II Study of SB-497115-GR in Hepatitis C Virus Infected Patients [Phase 2]
Phase II Japanese study of SB-497115-GR in chronic hepatitis C has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: Efficacy of a 12-Week Regimen of Telaprevir, Pegylated Interferon, and Ribavirin in Treatment-Naive and Prior Relapser Subjects With Interleukin28B (IL28B) CC Genotype [Phase 3]
Phase 3 trial evaluating a 12-week regimen of telaprevir with pegylated interferon and ribavirin in treatment-naive and prior relapser chron…
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CLINICAL_TRIALS trial_result · 2015-02-10Clinical Trial Update: Study of Drug Combination on Pharmacokinetics in Healthy Volunteers [Phase 1]
A Phase 1 study evaluating the pharmacokinetics of a drug combination in healthy volunteers for hepatitis C has completed.
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CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: Safety, Tolerability, PK and PD of SCH 900518 in Naive or Treatment-Experienced Subjects Infected With HCV Genotype 1 (Protocol No. P04695) [Phase 1]
Phase 1 study evaluating safety, tolerability, PK and PD of SCH 900518 in adults with chronic hepatitis C (genotype 1) has completed.
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CLINICAL_TRIALS trial_result · 2015-02-06Clinical Trial Update: Safety and Antiviral Activity of IDX184 in Combination With Pegylated Interferon and Ribavirin for 12 Weeks (MK-2355-005) [Phase 2]
Phase 2 trial results evaluate the safety and antiviral activity of IDX184 in combination with pegylated interferon and ribavirin over 12 we…
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CLINICAL_TRIALS trial_result · 2015-02-05Clinical Trial Update: Safety, Pharmacokinetics, and Pharmacodynamics of MK-6325 in Hepatitis C Virus (HCV) Infections (MK-6325-003) [Phase 1]
This update reports safety, pharmacokinetics, and pharmacodynamics data from Phase 1 testing of MK-6325 in hepatitis C virus infections. The…
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CLINICAL_TRIALS trial_result · 2015-02-04Clinical Trial Update: Safety, Tolerability, and Efficacy of 12-weeks of Sovaprevir, ACH-3102, and Ribavirin in Treatment-naive GT-1 HCV Participants [Phase 2]
Phase 2 trial assessing 12 weeks of Sovaprevir, ACH-3102, and Ribavirin in treatment-naive genotype-1 hepatitis C patients; study completed …
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CLINICAL_TRIALS trial_result · 2015-02-04Clinical Trial Update: Safety and Efficacy of PegIntron and Rebetol Combination Therapy in Patients With Chronic Hepatitis C in Japan (Study P04505)
A completed Japanese study assessing the safety and efficacy of PegIntron (pegylated interferon alfa-2b) plus Rebetol (ribavirin) in chronic…
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CLINICAL_TRIALS trial_result · 2015-02-03Clinical Trial Update: Safety and Efficacy of PegIntron Plus Rebetol in Patients With Chronic Hepatitis C in Japan, Excluding (1) Subjects With HCV Genotype 1 and High Viral Load, and (2) Interferon-naïve Subjects With Low Viral Load (Study P04841)(COMPLETED)
This completed Japanese trial assessed safety and efficacy of PegIntron plus Rebetol in chronic hepatitis C, excluding genotype 1 with high …
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CLINICAL_TRIALS trial_result · 2015-01-28Clinical Trial Update: Safety and Efficacy Study of Peginterferon Lambda-1a vs. Peginterferon Alfa-2a, Plus Ribavirin in Subjects With Genotype 1 Hepatitis C [Phase 3]
This document reports the completion of a Phase 3 safety and efficacy trial comparing Peginterferon Lambda-1a to Peginterferon Alfa-2a plus …
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CLINICAL_TRIALS trial_result · 2015-01-26Clinical Trial Update: Study of ABT-267 in Treatment Naive Hepatitis C Virus (HCV) Genotype 1 Infected Subjects [Phase 2]
Phase 2 study of ABT-267 in treatment-naive hepatitis C virus genotype 1 infection completed; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-01-22Clinical Trial Update: A Multiple Dose Study to Evaluate the Safety and Efficacy of MK-2748 in Hepatitis C-Infected Participants (MK-2748-002 AM1) [Phase 1]
Phase 1 multiple-dose trial assessing the safety and preliminary efficacy of MK-2748 in participants with Hepatitis C; the study has complet…
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CLINICAL_TRIALS trial_result · 2015-01-22Clinical Trial Update: A Pharmacokinetics/Pharmacodynamics Study of SCH 900518 in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C (Protocol No. P05104AM2)(COMPLETED) [Phase 2]
This is a completed Phase 2 pharmacokinetics/pharmacodynamics study of SCH 900518 in previously untreated subjects with genotype 1 chronic h…
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CLINICAL_TRIALS trial_result · 2015-01-21Clinical Trial Update: Study of Sirolimus Versus Mycophenolate Liver Transplant Recipients With Recurrent Hepatitis C Virus (HCV) [Phase 4]
Phase 4 clinical trial comparing sirolimus versus mycophenolate in liver transplant recipients with recurrent hepatitis C; results were post…
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CLINICAL_TRIALS trial_result · 2015-01-15Clinical Trial Update: A Pilot Study To Evaluate the Efficacy of Response Guided Therapy of Peginterferon Alfa Plus Ribavirin in the Treatment of Patients With HCV/HBV Co-Infection [Phase 4]
A Phase 4 pilot study evaluating response-guided therapy with pegylated interferon alfa plus ribavirin in patients with hepatitis B and hepa…
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CLINICAL_TRIALS trial_result · 2015-01-14Clinical Trial Update: Efficacy of Pegylated Interferon Plus Ribavirin Plus Nitazoxanide in HCV Genotype 4 and HIV Coinfection [Phase 2]
Phase 2 clinical trial evaluating the efficacy of pegylated interferon plus ribavirin plus nitazoxanide in patients with Hepatitis C genotyp…
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CLINICAL_TRIALS trial_result · 2015-01-12Clinical Trial Update: Pegylated Interferon, Ribavirin, Telaprevir in Hepatitis C Virus Infection in Orthotopic Liver Transplant Recipients [Phase 4]
Phase 4 clinical trial evaluating pegylated interferon, ribavirin, and telaprevir for Hepatitis C in liver transplant recipients; the study …
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CLINICAL_TRIALS trial_result · 2015-01-09Clinical Trial Update: Two-way Interaction Between Alisporivir and EDP239 [Phase 1]
A Phase 1 study evaluated the pharmacokinetic and safety interaction between alisporivir and EDP239 in Hepatitis C and has completed.
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: A Randomized Study to Evaluate the Safety, Tolerability and Antiviral Activity of ABT-450, ABT-333 and ABT-072 [Phase 2]
A Phase 2 randomized study evaluated the safety, tolerability, and antiviral activity of ABT-450, ABT-333, and ABT-072 in Hepatitis C; the t…