Hepatitis C
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: An Efficacy, Pharmacokinetics, Safety and Tolerability Study of TMC435 as Part of a Treatment Regimen for Hepatitis C-Infected Patients [Phase 3]
Phase 3 study results for TMC435 in a hepatitis C treatment regimen, reporting efficacy, pharmacokinetics, safety and tolerability.
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CLINICAL_TRIALS trial_result · 2015-08-10Clinical Trial Update: Open Label Single Dose Phase I Trial of BI 201335 to Study Pharmacokinetics and Safety in Patients With Compensated Liver Cirrhosis [Phase 1]
Open-label Phase I single-dose pharmacokinetics and safety study of BI 201335 in patients with compensated liver cirrhosis and Hepatitis C; …
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: A Triple Combination Therapy Study of Boceprevir, Pegasys and Copegus in Previously Untreated Patients With Genotype 1 Chronic Hepatitis C [Phase 4]
A Phase 4 clinical trial evaluating a triple therapy of boceprevir, pegylated interferon alfa-2a (Pegasys) and ribavirin (Copegus) in previo…
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: Biliverdin Reductase A in Chronic Hepatitis C Virus Infection
A completed clinical trial at Charles University evaluated biliverdin reductase A in people with chronic hepatitis C infection.
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CLINICAL_TRIALS trial_result · 2015-08-07Clinical Trial Update: Analysis of Host Genetic Factors in the Occurrence of Anemia and on the Virological Response to a Peg-interferon/Ribavirin Therapy in HIV-HCV Co-infected Patients [NA]
This completed clinical trial analyzed host genetic factors to understand anemia risk and virological response to Peg-interferon plus ribavi…
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CLINICAL_TRIALS trial_result · 2015-08-05Clinical Trial Update: Hepatic Safety of Eviplera® in HIV/Hepatitis C (HCV)-Coinfected Patients Without HCV Treatment in the "The HEPAVIR HEPATIC SAFETY Cohort."
Completed cohort study evaluating the hepatic safety of Eviplera (rilpivirine/emtricitabine/tenofovir disoproxil fumarate) in HIV/HCV coinfe…
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CLINICAL_TRIALS trial_result · 2015-08-04Clinical Trial Update: A Study to Evaluate the Safety and Effect of Co-administration of ABT-450 With Ritonavir (ABT-450/r) and ABT-267 in Adults With Chronic Hepatitis C Virus Infection [Phase 2]
A Phase 2 study assessing safety and effect of combining ABT-450/r with ABT-267 in adults with chronic hepatitis C; study completed with res…
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: Japanese Pegylated Interferon (PegIFN) Alfa-2b/Ribavirin (RBV) Combination Trial [Phase 3]
A Phase 3 trial in Japan evaluating pegylated interferon alfa-2b in combination with ribavirin for hepatitis C has completed and results wer…
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: Drug Interaction Study With BI 201335 and Methadone or Buprenorphine/Naloxone [Phase 1]
Phase 1 drug interaction study evaluating BI 201335 with methadone or buprenorphine/naloxone in hepatitis C patients; results posted in 2015…
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CLINICAL_TRIALS trial_result · 2015-08-03Clinical Trial Update: Drug-drug Interaction of BI 201335 and Microgynon [Phase 1]
Phase 1 trial evaluating the drug-drug interaction between Boehringer Ingelheim's BI 201335 (faldaprevir) and Microgynon in adults with chro…
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CLINICAL_TRIALS trial_result · 2015-07-31Clinical Trial Update: A Rollover Study of BI 201335 in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-experienced Genotype 1 Hepatitis C Infected Patients [Phase 3]
A Phase 3 rollover study of BI 201335 in combination with pegylated interferon-alpha and ribavirin in treatment-experienced genotype 1 hepat…
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CLINICAL_TRIALS trial_result · 2015-07-31Clinical Trial Update: Pharmacokinetics and Safety of BI 201335 in Patients With Mild to Severe Renal Impairment [Phase 1]
Phase 1 trial assessing the pharmacokinetics and safety of BI 201335 in Hepatitis C patients with varying degrees of renal impairment; resul…
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CLINICAL_TRIALS trial_result · 2015-07-31Clinical Trial Update: Bioequivalence Trial of 2 Dose Strengths of BI 201335 NA Soft Gelatine Capsules [Phase 1]
A Phase 1 bioequivalence trial comparing two dose strengths of BI 201335 NA soft gelatin capsules has completed, with results posted in July…
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CLINICAL_TRIALS trial_result · 2015-07-31Clinical Trial Update: Status of Chronic Liver Disease in Hepatitis C Virus (HCV) Patients Coinfected With Human Immunodeficiency Virus (HIV) in Andalusia
This entry provides a status update for a clinical trial on chronic liver disease in patients coinfected with hepatitis C virus and HIV in A…
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CLINICAL_TRIALS trial_result · 2015-07-29Clinical Trial Update: Behavioral Science Aspects of Rapid Test Acceptance [NA]
A completed study from California State University, Long Beach examined behavioral factors influencing acceptance of rapid diagnostic tests …
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CLINICAL_TRIALS trial_result · 2015-07-29Clinical Trial Update: Sustained Virological Response (SVR)Rate of Pegasys Plus Ribavirin in Patients With Chronic Hepatitis C [NA]
A terminated clinical trial assessing the sustained virological response rate of Pegasys plus ribavirin in patients with chronic hepatitis C…
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CLINICAL_TRIALS trial_result · 2015-07-27Clinical Trial Update: Safety and Pharmacokinetics of MK-7680 in Participants With Hepatitis C (MK-7680-003) [Phase 1]
Phase 1 study evaluating the safety and pharmacokinetics of the investigational drug MK-7680 in participants with hepatitis C; the trial is …
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CLINICAL_TRIALS trial_result · 2015-07-24Clinical Trial Update: A Study of The Relationship Between Drop in Hemoglobin and Sustained Virological Response in Patients With Chronic Hepatitis C Treated With Copegus (Ribavirin) and Pegasys (Peginterferon Alfa-2a) [Phase 4]
Phase 4 study evaluating whether drop in hemoglobin predicts sustained virological response in chronic hepatitis C patients treated with rib…
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CLINICAL_TRIALS trial_result · 2015-07-21Clinical Trial Update: An Open-label Randomized Multicenter Phase III Clinical Study Comparing Safety and Efficacy of Algeron (Cepeginterferon Alfa-2b) and and PegIntron (Peginterferon Alfa-2b) in Combination With Ribavirin as Combined Treatment of Chronic Hepatitis C in Human Immunodeficiency Virus-1 Infected Patients [Phase 3]
Phase III open-label trial comparing Algeron (cepeginterferon alfa-2b) with PegIntron (peginterferon alfa-2b) plus ribavirin in HIV-coinfect…
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CLINICAL_TRIALS trial_result · 2015-07-21Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of MK-8325 in Hepatitis C-Infected Males (MK-8325-002) [Phase 1]
Phase 1 study evaluating safety, pharmacokinetics and pharmacodynamics of MK-8325 in men with chronic hepatitis C; the trial was terminated.
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CLINICAL_TRIALS trial_result · 2015-07-15Clinical Trial Update: Register of Telaprevir and Boceprevir in Routine Clinical Practice
This clinical trial update reports on the use of telaprevir and boceprevir in routine clinical practice for hepatitis C, based on a national…
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CLINICAL_TRIALS trial_result · 2015-07-14Clinical Trial Update: Chronic Hepatitis C and Insulin Resistance
A Garvan Institute-sponsored clinical trial examining hepatitis C and insulin resistance has completed.
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CLINICAL_TRIALS trial_result · 2015-07-13Clinical Trial Update: Boceprevir Drug Combination for Hepatitis C Treatment in People With and Without HIV [Phase 4]
Phase 4 trial evaluating boceprevir in combination with standard hepatitis C therapy in people with and without HIV was terminated; results …
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CLINICAL_TRIALS trial_result · 2015-07-09Clinical Trial Update: Observational Study on Prevalence of Host and Viral Genotypes in Chronic Hepatitis B and Hepatitis C Patients in India
This completed observational clinical trial assessed the prevalence of host and viral genotypes in chronic hepatitis B and hepatitis C patie…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 201335 as Softgel Capsule in Naive Hepatitis C Virus (HCV) Patients [Phase 2]
Phase 2 trial evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of escalating oral doses of BI 201335 in treatment-naïv…