Hepatitis C
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CLINICAL_TRIALS trial_result · 2015-10-06Clinical Trial Update: Three-year Follow-up of Participants After Administration of Boceprevir or Narlaprevir for the Treatment of Chronic Hepatitis C (P05063) [Phase 2, Phase 3]
Three-year follow-up results from a trial comparing boceprevir and narlaprevir in chronic hepatitis C were reported after termination.
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Quantification of Side Effects During Hepatitis C Therapy
The document provides quantified data on the side effects observed during hepatitis C therapy in a completed clinical trial led by Medical U…
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: Evaluating the Role of Immune Responses in the Emergence of Protease Inhibitor Mutations
This completed University of Cincinnati trial studied how immune responses may influence the emergence of mutations in protease inhibitors f…
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Efficacy and Safety of Sofosbuvir/Ledipasvir Fixed-Dose Combination ± Ribavirin in Cirrhotic Subjects With Chronic Genotype 1 HCV Infection [Phase 2]
Phase 2 trial update evaluating sofobuvir/ledipasvir with or without ribavirin in cirrhotic patients with chronic genotype 1 hepatitis C vir…
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Efficacy and Safety Study of PEG-IFN-SA and Ribavirin to Treat Chronic Hepatitis C [Phase 3]
Phase 3 clinical trial evaluating PEG-IFN-SA plus ribavirin for chronic hepatitis C has completed; no efficacy or safety results are describ…
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CLINICAL_TRIALS trial_result · 2015-09-23Clinical Trial Update: A Pilot Study of the Grapefruit Flavonoid Naringenin for HCV Infection [Phase 1]
A Phase 1 pilot study evaluating the grapefruit flavonoid naringenin for hepatitis C virus infection has completed.
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CLINICAL_TRIALS trial_result · 2015-09-21Clinical Trial Update: Triple-Therapy in Patients With HCV Genotype 3 Who Previously Failed Treatment [Phase 3]
A Phase 3 clinical trial update reports results for triple-therapy in patients with Hepatitis C genotype 3 who previously failed treatment.
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CLINICAL_TRIALS trial_result · 2015-09-18Clinical Trial Update: Efficacy and Safety of BI 201335 (Faldaprevir) in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-naïve Genotype 1 Hepatitis C Infected Patients (STARTverso 2) [Phase 3]
Phase 3 STARTverso 2 trial evaluated faldaprevir in combination with pegylated interferon-alfa and ribavirin for treatment-naïve genotype 1 …
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CLINICAL_TRIALS trial_result · 2015-09-18Clinical Trial Update: Efficacy and Safety of BI 201335 (Faldaprevir) in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-naïve Genotype 1 Hepatitis C Infected Patients (STARTverso 1) [Phase 3]
This Phase 3 trial evaluates faldaprevir in combination with pegylated interferon-alpha and ribavirin in treatment-naïve genotype 1 hepatiti…
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CLINICAL_TRIALS trial_result · 2015-09-18Clinical Trial Update: UNITY 3: A Japanese Phase 3 Study of a Daclatasvir/Asunaprevir/BMS-791325 in Subjects With Genotype 1 Chronic Hepatitis C [Phase 3]
Phase 3 Japanese UNITY 3 trial evaluating daclatasvir/asunaprevir/BMS-791325 in genotype 1 chronic hepatitis C has completed.
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Safety, Antiviral Activity and PK of MRD of BI 201335 in Chronic Hepatitis C Patients Both Treatment Naive and -Experienced [Phase 1]
Phase 1 clinical trial update on safety, antiviral activity, and pharmacokinetics of BI 201335 in treatment-naïve and experienced chronic he…
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CLINICAL_TRIALS trial_result · 2015-09-16Clinical Trial Update: BMS-790052 (Daclatasvir) Plus Peg-Interferon Alfa-2a and Ribavirin in Treatment-Naive Black/African-Americans, Latinos and White/Caucasians With Hepatitis C [Phase 3]
Phase 3 clinical trial evaluating daclatasvir in combination with peg-interferon alfa-2a and ribavirin in treatment-naive patients with Hepa…
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CLINICAL_TRIALS trial_result · 2015-09-16Clinical Trial Update: Study to Assess the Effect of BMS-790052 on the Pharmacokinetics of Ortho Tri-Cyclen® in Healthy Female Subjects [Phase 1]
Phase 1 pharmacokinetic interaction study to evaluate how daclatasvir (BMS-790052) affects the plasma levels of Ortho Tri-Cyclen in healthy …
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CLINICAL_TRIALS trial_result · 2015-09-14Clinical Trial Update: Phase III Daclatasvir and Sofosbuvir for Genotype 3 Chronic HCV [Phase 3]
Phase III trial evaluating the combination of daclatasvir and sofosbuvir for genotype 3 chronic hepatitis C completed with results posted in…
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CLINICAL_TRIALS trial_result · 2015-09-11Clinical Trial Update: Safety and Efficacy of Daclatasvir (BMS-790052) Plus Standard of Care in Japanese Patients (Pegylated-interferon Alpha-2a and Ribavirin) [Phase 2]
Phase 2 study evaluating daclatasvir with standard of care (pegylated interferon alfa-2a and ribavirin) in Japanese patients with Hepatitis …
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CLINICAL_TRIALS trial_result · 2015-09-10Clinical Trial Update: A Single Ascending Dose Study of Daclatasvir (BMS-790052) in Hepatitis C Virus Infected Subjects [Phase 1, Phase 2]
A clinical trial update reporting results from a single ascending-dose study of Daclatasvir (BMS-790052) in chronic hepatitis C patients, co…
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: Phase III BMS-790052 Add-On to Peg-Interferon Alfa-2a and Ribavirin in Naive Hepatitis C [Phase 3]
Phase III trial evaluating BMS-790052 (daclatasvir) added to pegylated interferon alfa-2a and ribavirin in treatment-naive hepatitis C patie…
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: Short Term Treatment With BI 201335, Peginterferon-alpha 2a and Ribavirin in Hepatitis c Virus Genotype-1 Treatment-naïve Patients (SILEN-C3) [Phase 2]
A Phase 2 study (SILEN-C3) evaluated short-term treatment with BI 201335 in combination with peginterferon-alfa-2a and ribavirin in genotype…
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CLINICAL_TRIALS trial_result · 2015-09-07Clinical Trial Update: Comparison of Plasma & SMARTplasma for Human Immunodeficiency Virus (HIV) and Hepatitis C Virus (HCV) Antibody Testing
A completed clinical trial compared Plasma and SMARTplasma antibody tests for detecting HIV and Hepatitis C antibodies.
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: Phase III Trial of BI 201335 (Faldaprevir) in Treatment Naive (TN) and Relapser Hepatitis C Virus (HCV)-Human Immunodeficiency Virus (HIV) Coinfected Patients (STARTverso 4) [Phase 3]
Phase III trial of faldaprevir in treatment-naive and relapser Hepatitis C patients co-infected with HIV has completed with results posted.
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CLINICAL_TRIALS trial_result · 2015-09-04Clinical Trial Update: Peginterferon Plus Ribavirin for Hepatitis C Patients Concomitant With Malignancy Other Than Hepatocellular Carcinoma [Phase 4]
Phase 4 trial evaluating pegylated interferon plus ribavirin in chronic hepatitis C patients with other malignancies (not hepatocellular car…
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Treatment of Recently Acquired Hepatitis C Virus Infection [Phase 4]
This clinical trial report summarizes a Phase 4 study evaluating treatment for recently acquired Acute Hepatitis C; the study has completed.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Comparative Trial of Standard Versus Low-dose Peg-Interferon Plus Ribavirin in the Treatment of Chronic Hepatitis C
A completed comparative clinical trial evaluated standard-dose versus low-dose pegylated interferon plus ribavirin for chronic hepatitis C.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Low-dose Peg-interferon Plus Ribavirin (IFN/RBV) for Prevention of Hepatocellular Carcinoma (HCC) Recurrence in Patients Who Had Surgery to Remove Primary HCC [Phase 4]
Phase 4 clinical trial evaluating low-dose pegylated interferon plus ribavirin to prevent hepatocellular carcinoma recurrence after surgical…
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CLINICAL_TRIALS trial_result · 2015-08-18Clinical Trial Update: Algeron (Cepeginterferon Alfa-2b) Compared With PegIntron (Peginterferon Alfa-2b) for Treatment of Chronic Hepatitis C [Phase 2, Phase 3]
A completed Phase 2/3 trial comparing Algeron (cepeginterferon alfa-2b) with PegIntron (peginterferon alfa-2b) for chronic hepatitis C, with…