Hepatitis C
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CLINICAL_TRIALS trial_result · 2015-12-29Clinical Trial Update: A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of VX-135 and Daclatasvir in Subjects With Genotype 1 Chronic Hepatitis C Chronic Hepatitis C [Phase 2]
Completed Phase 2 trial evaluating the safety, efficacy, pharmacokinetics, and pharmacodynamics of VX-135 in combination with daclatasvir fo…
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CLINICAL_TRIALS trial_result · 2015-12-28Clinical Trial Update: Efficacy and Safety of Daclatasvir Plus Asunaprevir in Chronic Hepatitis C [Phase 4]
A Phase 4 clinical trial update evaluates the efficacy and safety of combining daclatasvir and asunaprevir for chronic hepatitis C.
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CLINICAL_TRIALS trial_result · 2015-12-23Clinical Trial Update: Therapy With Ledipasvir/Sofosbuvir in Patients With Genotype 1 HCV Infection Receiving Opiate Substitution Therapy [Phase 4]
Phase 4 clinical trial update assessing Ledipasvir/Sofosbuvir in genotype 1 hepatitis C virus infection patients receiving opiate substituti…
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: Safety and Efficacy Study of Daclatasvir (BMS-790052) Plus Pegylated Interferon-Alfa 2a and Ribavirin in Patients Coinfected With Untreated Hepatitis C Virus and HIV Virus [Phase 3]
Phase 3 safety and efficacy study of daclatasvir with pegylated interferon alfa-2a and ribavirin in patients with untreated hepatitis C geno…
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CLINICAL_TRIALS trial_result · 2015-12-17Clinical Trial Update: Transfusion Associated HCV in a Pediatric Population
This clinical trial update reports the completion of a pediatric study investigating transfusion-associated Hepatitis C and GB virus C infec…
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: Study in Genotype 2 or 3 Patients With Chronic Hepatitis Virus Infection [Phase 2]
A Phase 2 study in patients with chronic hepatitis C virus infection, genotype 2 or 3, has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: An Observational Study on Predictive Factors of Response in Patients With Chronic Hepatitis C Treated With Pegasys (Peginterferon Alfa-2a) and Ribavirin
An observational study reported results on predictive factors of response in patients with chronic hepatitis C treated with Pegasys (peginte…
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CLINICAL_TRIALS trial_result · 2015-12-09Clinical Trial Update: Impact of Moderate Alcohol Use on Hepatitis C Virus (HCV) Progression
A completed clinical trial investigating whether moderate alcohol use influences progression of Hepatitis C infection and associated liver f…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Pilot Study of Hepatitis C Virus Entry Inhibitor (ITX 5061) in Liver Transplant Recipients [Phase 1]
Phase 1 pilot study of the hepatitis C virus entry inhibitor ITX 5061 in liver transplant recipients has completed. The update summarizes th…
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Study of Daclatasvir (BMS-790052) and Simeprevir (TMC435) in Patients With Genotype 1 Chronic Hepatitis C Virus [Phase 2]
A Phase 2 trial evaluating the combination of daclatasvir and simeprevir in genotype 1 chronic hepatitis C infection; results were posted in…
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Study Assessing the Effects of Darunavir/Ritonavir or Lopinavir/Ritonavir on the Pharmacokinetics of Daclatasvir in Healthy Participants [Phase 1]
Phase 1 pharmacokinetic study to evaluate whether coadministration of darunavir/ritonavir or lopinavir/ritonavir affects the pharmacokinetic…
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CLINICAL_TRIALS trial_result · 2015-11-26Clinical Trial Update: A Phase 1a/1b Study of PPI-383 in Healthy Adults and Hepatitis C Patients [Phase 1]
Phase 1a/1b trial evaluating PPI-383 in healthy adults and chronic hepatitis C patients has completed.
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CLINICAL_TRIALS trial_result · 2015-11-26Clinical Trial Update: Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) in Japanese Adults With Subgenotype 1b Chronic Hepatitis C Virus (HCV) Infection [Phase 3]
This Phase 3 trial evaluated the efficacy and safety of the paritaprevir/ritonavir/ombitasvir regimen (ABT-450/r/ABT-267, Technivie) in Japa…
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CLINICAL_TRIALS trial_result · 2015-11-26Clinical Trial Update: A Study to Evaluate ABT-450 With Ritonavir (ABT-450/r) and ABT-267 in Japanese Adults With Chronic Hepatitis C Virus Infection [Phase 2]
Phase 2 study evaluating ABT-450/r and ABT-267 in Japanese adults with chronic hepatitis C completed; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-11-25Clinical Trial Update: Study of PPI-668, BI 207127 and Faldaprevir, With and Without Ribavirin, in the Treatment of Chronic Hepatitis C [Phase 2]
A Phase 2 trial evaluating combinations of PPI-668, BI 207127, and faldaprevir with and without ribavirin for chronic hepatitis C has comple…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: BI 207127 / Faldaprevir Combination Therapy in Hepatic Impairment (Child-Pugh B) Patients With Genotype 1b Chronic Hepatitis C Infection: HCVerso3 [Phase 2]
Phase 2 study evaluating faldaprevir (BI 207127) in combination therapy for genotype 1b chronic hepatitis C in patients with hepatic impairm…
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CLINICAL_TRIALS trial_result · 2015-11-16Clinical Trial Update: Antiviral Effect, Safety, and Pharmacokinetics of BI201335 +PegIFN/RBV in HCV-GT1 (SILEN-C1&2) [Phase 2]
Phase 2 study assessing antiviral effect, safety, and pharmacokinetics of Boehringer Ingelheim BI-201335 combined with PegIFN/RBV in chronic…
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CLINICAL_TRIALS trial_result · 2015-11-16Clinical Trial Update: Pharmacokinetic and Safety Study of Daclatasvir in Patients With Renal Impairment [Phase 1]
Phase 1 pharmacokinetic and safety study evaluating daclatasvir in patients with renal impairment to assess drug exposure and tolerability.
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CLINICAL_TRIALS trial_result · 2015-11-11Clinical Trial Update: Hepatic Safety of Currently Used Antiretroviral Regimens in Patients With Chronic Hepatitis Under Real Life Conditions
This clinical trial update assesses the hepatic safety of currently used antiretroviral regimens in patients with chronic hepatitis and HIV …
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CLINICAL_TRIALS trial_result · 2015-11-09Clinical Trial Update: Open-Label Study of Sofusbuvir+Ribavirin With or Without Peginterferon Alfa-2a in Subjects With Chronic HCV Infection Who Participated in Prior Gilead HCV Studies [Phase 3]
Open-label Phase 3 study evaluating sofosbuvir plus ribavirin with or without peginterferon alfa-2a in chronic hepatitis C patients who prev…
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Chronically-infected HCV Genotype 2 and 3 Treatment-naive Subjects: Part A: Safety and Efficacy of INX-08189 With Peg IFN Alfa-2a and Ribavirin. Part B: INX-08189 in Interferon Free Treatment With Daclatasvir and/or Ribavirin [Phase 2]
Phase 2 clinical trial update for INX-08189 in treatment-naive chronic hepatitis C patients with genotypes 2 and 3, assessing INX-08189 with…
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CLINICAL_TRIALS trial_result · 2015-11-03Clinical Trial Update: UNITY 1: A Study of an Investigational Treatment Regimen of Daclatasvir (DCV) + Asunaprevir (ASV) + BMS-791325 in a Fixed Dose Combination (the DCV 3DAA (Direct Acting Antiviral) Regimen) for 12 Weeks for the Treatment of Chronic Hepatitis C Virus (HCV) Genotype 1 Infection in Non-cirrhotic Subjects [Phase 3]
This document reports the completion of the Phase 3 UNITY 1 trial evaluating a fixed-dose combination of daclatasvir, asunaprevir, and BMS-7…
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CLINICAL_TRIALS trial_result · 2015-11-03Clinical Trial Update: Adherence in Patients Receiving PegIntron and Rebetol for Hepatitis C in Conjunction With a Patient Assistance Program (Study P04206)
A terminated clinical trial update reports adherence data for patients with chronic hepatitis C treated with PegIntron and Rebetol under a p…
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CLINICAL_TRIALS trial_result · 2015-10-28Clinical Trial Update: Efficacy and Safety of BI 201335 (Faldaprevir) in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-Experienced Genotype 1 Hepatitis C Infected Patients (STARTverso 3) [Phase 3]
Phase 3 STARTverso 3 trial evaluated faldaprevir in combination with pegylated interferon-alfa and ribavirin in treatment-experienced genoty…
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CLINICAL_TRIALS trial_result · 2015-10-28Clinical Trial Update: Viral Load Changes in Lymphoma Patients With HCV Infection After Chemotherapy
A clinical trial update examining viral load changes in lymphoma patients with hepatitis C infection after chemotherapy.