Hepatitis C
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: 4 Week Combination of BI 207127 NA With Peg-IFN and Ribavirin in Chronic HCV Patients [Phase 1]
Phase 1 study from Boehringer Ingelheim evaluating a 4-week combination of BI 207127 with Pegylated interferon and ribavirin in patients wit…
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Rapid Hepatitis C Elimination Trial- A Pilot Study of Daclatasvir/Asunaprevir/BMS-791325 With or Without Ribavirin To Treat Hepatitis C Virus [NA]
A completed pilot trial evaluating a three-drug regimen—Daclatasvir, Asunaprevir, and BMS-791325—with or without Ribavirin for Hepatitis C.
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: IFN-free Combination Therapy in HCV-infected Patients Treatment-naive:HCVerso1 [Phase 3]
Phase 3 trial of an interferon-free combination therapy for treatment-naive chronic hepatitis C patients (HCVerso1) completed with results p…
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C Infection (CHC). [Phase 4]
A Phase 4 study assessing peginterferon alfa-2a with ribavirin in interferon-naive patients with chronic hepatitis C; results were posted in…
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: Ledipasvir/Sofosbuvir Fixed-Dose Combination + Ribavirin in Subjects With Chronic HCV With Advanced Liver Disease or Post-Liver Transplant [Phase 2]
Phase 2 trial evaluating a fixed-dose combination of ledipasvir/sofosbuvir with ribavirin in adults with chronic hepatitis C and advanced li…
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: This Trial Evaluates Safety, Pharmacokinetic Profile and Anti-viral Response of BI 207127 and BI 201335 for Patients With Chronic Hepatitis C [Phase 2]
Phase 2 trial evaluating safety, pharmacokinetics, and antiviral response of Boehringer Ingelheim compounds BI-207127 and BI-201335 in patie…
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CLINICAL_TRIALS trial_result · 2016-04-12Clinical Trial Update: Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Participants With Chronic Hepatitis C Virus Infection Without Cirrhosis [Phase 3]
Phase 3 trial evaluating the efficacy and safety of combining Simeprevir with Sofosbuvir in adults with chronic hepatitis C without cirrhosi…
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CLINICAL_TRIALS trial_result · 2016-04-12Clinical Trial Update: Study of Efficacy and Safety of Grazoprevir (MK-5172)/Elbasvir (MK-8742) Combination Regimen for Treatment-Naïve Participants With Chronic Hepatitis C Virus Genotypes 1, 4, and 6 (MK-5172-060) [Phase 3]
Phase 3 study of grazoprevir/elbasvir in treatment-naïve chronic hepatitis C patients showed completed results with posted outcomes in 2016.
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CLINICAL_TRIALS trial_result · 2016-04-12Clinical Trial Update: Safety and Efficacy of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Participants With Chronic Hepatitis C and Chronic Kidney Disease (MK-5172-052) [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating the safety and efficacy of Grazoprevir and Elbasvir in participants with chronic hepatitis C and chronic …
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Hepatitis C Translating Initiatives for Depression Into Effective Solutions [NA]
This VA-sponsored trial evaluating interventions for depression in people with Hepatitis C has completed, and its results were posted in Apr…
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Paroxetine for the Treatment of Interferon Related Side Effects for Hepatitis C [NA]
Completed clinical trial assessing paroxetine for managing interferon-related side effects in hepatitis C, with depression noted as a coexis…
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CLINICAL_TRIALS trial_result · 2016-04-08Clinical Trial Update: Follow-up Study of Patients Who Experienced Thromboembolic Events in the ENABLE Studies
This is a clinical trial update describing a follow-up study of patients who experienced thromboembolic events in the ENABLE studies for Hep…
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CLINICAL_TRIALS trial_result · 2016-04-07Clinical Trial Update: A Study of the Efficacy and Safety of PPI-668 (NS5A Inhibitor) Plus Sofosbuvir, With or Without Ribavirin, in Patients With Chronic Hepatitis C Genotype-4 [Phase 2, Phase 3]
This clinical trial update outlines a combined Phase 2/3 study of PPI-668 (NS5A inhibitor) with Sofosbuvir, with or without Ribavirin, for c…
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CLINICAL_TRIALS trial_result · 2016-04-05Clinical Trial Update: SYREN Study: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Copegus (Ribavirin) in Non-Responder Patients With Chronic Hepatitis C (CHC) Genotype 1. [Phase 4]
This trial update reports on the Phase 4 SYREN study evaluating PEGASYS (peginterferon alfa-2a, 40 kDa) plus Copegus (ribavirin) in non-resp…
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Participants With Genotype 1 Chronic Hepatitis C Virus Infection and Cirrhosis [Phase 3]
Phase 3 trial evaluating the efficacy and safety of combining simeprevir with sofosbuvir in genotype 1 chronic hepatitis C with cirrhosis; r…
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: A Study of TMC435 in Combination With Peginterferon Alfa-2A and Ribavirin for Hepatitis C Virus Genotype-1 Infected Patients Who Participated in a Control Group of a TMC435 Study [Phase 3]
This Phase 3 trial update notes the completion of a study evaluating TMC435 in combination with peginterferon alfa-2a and ribavirin in hepat…
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CLINICAL_TRIALS trial_result · 2016-04-01Clinical Trial Update: Dutch Acute HCV in HIV Study (DAHHS) [Phase 2]
The Dutch Acute HCV in HIV Study (DAHHS), a Phase 2 trial, has completed enrollment with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: Efficacy of an Exercise Intervention to Decrease Depressive Symptoms in Veterans With Hepatitis C [NA]
A completed clinical trial evaluated whether an exercise program reduces depressive symptoms in veterans with hepatitis C.
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: Study of Efficacy and Safety of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Chronic Hepatitis C Participants With Child-Pugh (CP)-B Hepatic Insufficiency (MK-5172-059) [Phase 2, Phase 3]
Study evaluating the efficacy and safety of grazoprevir and elbasvir in chronic hepatitis C patients with Child-Pugh B hepatic insufficiency…
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CLINICAL_TRIALS trial_result · 2016-03-11Clinical Trial Update: An Observational Study on Long-Term Persistence of Resistant Mutations And Durability of Sustained Virological Response in Patients With Chronic Hepatitis C Treated With Direct Acting Antiviral (DAA)- Containing Regimens
This terminated observational study evaluated how long resistance mutations persist and whether sustained virologic response endures in pati…
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Sofosbuvir/Simeprevir Plus a Flat Dose of Ribavirin in Genotype 1 Elderly HCV Cirrhotic Patients [Phase 4]
Phase 4 trial assessing sofosbuvir/simeprevir plus a flat dose of ribavirin in genotype 1 elderly patients with liver cirrhosis; the study i…
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: An Efficacy and Safety Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in the Treatment of Chronic Hepatitis C Virus in Participants Who Are Co-Infected With Human Immunodeficiency Virus:C-EDGE CO-INFXN (MK-5172-061) [Phase 3]
Phase 3 clinical trial evaluating grazoprevir plus elbasvir in chronic hepatitis C patients co-infected with HIV; study completed with poste…
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Study of Efficacy and Safety of Grazoprevir (MK-5172) + Elbasvir (MK-8742) With or Without Ribavirin for Participants With Hepatitis C Genotype 1, 4, or 6 Infections Who Have Failed Prior Treatment With Pegylated Interferon + Ribavirin (MK-5172-068) [Phase 3]
Phase 3 trial assessing efficacy and safety of grazoprevir/elbasvir with or without ribavirin in Hepatitis C Genotypes 1, 4, or 6 after prio…
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Grazoprevir (MK-5172) With Peg-Interferon and Ribavirin in Participants With Chronic Genotype 2 or 3 Hepatitis C (MK-5172-012) [Phase 2]
Phase 2 trial evaluating grazoprevir with peg-interferon and ribavirin for chronic hepatitis C genotype 2 or 3; the study was terminated and…
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CLINICAL_TRIALS trial_result · 2016-03-04Clinical Trial Update: Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) + Ribavirin in Participants With Chronic Hepatitis C Who Failed Prior Direct-Acting Antiviral Therapy (MK-5172-048) [Phase 2]
Phase 2 study evaluating Grazoprevir + Elbasvir + Ribavirin in Chronic Hepatitis C patients who failed prior direct-acting antivirals; study…