Hepatitis C
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CLINICAL_TRIALS trial_result · 2016-12-29Clinical Trial Update: A Health Intervention to Prevent Depression Hepatitis C Patients [Phase 2, Phase 3]
The Phase 2/Phase 3 trial evaluating a health intervention to prevent depression in patients with Hepatitis C has been terminated.
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CLINICAL_TRIALS trial_result · 2016-12-29Clinical Trial Update: Acoustic Liver Biopsy in Normals and in Patients With Cirrhosis Using Endoscopic Ultrasound
A completed clinical trial evaluated acoustic liver biopsy via endoscopic ultrasound in healthy individuals and in patients with cirrhosis t…
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CLINICAL_TRIALS trial_result · 2016-12-29Clinical Trial Update: Tailored Regimens of PEGASYS® and Ribavirin for Genotype 1 Chronic Hepatitis C Patients Trial (TARGET-1) [Phase 4]
Phase 4 clinical trial update on tailored regimens of PEGASYS and ribavirin for genotype 1 chronic hepatitis C, now completed.
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Pioglitazone in Hepatitis C [Phase 4]
A Phase 4 clinical trial evaluating pioglitazone for chronic hepatitis C has completed.
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CLINICAL_TRIALS trial_result · 2016-12-15Clinical Trial Update: The Study of Safety, Pharmacokinetics, Pharmacodynamics of Peglamda (Peginterferon Lamda 1) on Healthy Volunteers and the Preliminary Evaluation of Peglamda and Hepasig (Ribavirin) Treatment's Effects on Chronic Hepatitis C Patients [Phase 1]
Phase 1 trial update evaluating the safety, pharmacokinetics, and pharmacodynamics of Peglamda (peginterferon lambda-1) in healthy volunteer…
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CLINICAL_TRIALS trial_result · 2016-12-14Clinical Trial Update: Sofosbuvir/Velpatasvir Fixed-Dose Combination in Adults With Chronic HCV Infection and Child-Pugh Class B Cirrhosis [Phase 3]
Phase 3 trial evaluating sofosbuvir/velpatasvir fixed-dose combination in adults with chronic hepatitis C and Child-Pugh B cirrhosis has com…
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CLINICAL_TRIALS trial_result · 2016-12-14Clinical Trial Update: PoC-HCV Genedrive Viral Detection Assay Validation Study
A completed clinical trial updating validation results for the Genedrive PoC-HCV Viral Detection Assay used for Hepatitis C detection.
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CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: Pilot Study Evaluating the Use of Simultaneous HBV, HCV, and HIV Rapid Tests [NA]
A pilot study evaluated the use of simultaneous rapid tests for HIV, hepatitis B, and hepatitis C; the trial is completed and results were p…
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir Co-Administered With Sofosbuvir With and Without Ribavirin in Treatment-Naive HCV Genotype 1-Infected Adults [Phase 3]
Phase 3 study evaluating co-administration of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir with and without Ribavirin in treatment-naive …
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis C [Phase 2]
A Phase 2 clinical trial reports treatment response in people with chronic hepatitis C, comparing outcomes in those with cirrhosis to those …
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: An Observational Study Examining the Use of Triple Combination Therapy With Boceprevir, Peginterferon Alfa-2a and Ribavirin in the Re-Treatment of Chronic Hepatitis C Patients
An observational study evaluating the re-treatment of chronic hepatitis C with a triple therapy of boceprevir, peginterferon alfa-2a, and ri…
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CLINICAL_TRIALS trial_result · 2016-12-08Clinical Trial Update: Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant [Phase 2]
A Phase 2 trial evaluating gradual withdrawal of immunosuppressive therapy in liver transplant recipients; results have been posted.
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination and Sofosbuvir + Ribavirin for Subjects With Chronic Hepatitis C Virus (HCV) and Inherited Bleeding Disorders [Phase 2]
Phase 2 study evaluating the efficacy and safety of ledipasvir/sofosbuvir fixed-dose combination and sofosbuvir plus ribavirin in adults wit…
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: Folinic Acid: Supplementation and Therapy [Phase 3]
The document reports the completion of a Phase 3 trial evaluating folinic acid supplementation and therapy in individuals with HIV infection…
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: Safety and Efficacy Study of Single Doses of TT-034 in Patients With Chronic Hepatitis C [Phase 1, Phase 2]
This clinical trial update documents the completion of a single-dose TT-034 safety and efficacy study in patients with chronic hepatitis C (…
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: Ledipasvir/Sofosbuvir Fixed-Dose Combination on Cerebral Metabolism and Neurocognition in Treatment-Naive and Treatment-Experienced Participants With Chronic Genotype 1 HCV Infection [Phase 2]
Phase 2 trial evaluating a fixed-dose combination of ledipasvir/sofosbuvir for chronic hepatitis C genotype 1, focusing on cerebral metaboli…
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CLINICAL_TRIALS trial_result · 2016-11-30Clinical Trial Update: Evaluation of a Multi-disciplinary Approach for the Treatment of Hepatitis C in IDUs (HI-LO Study) [NA]
This update announces the completion of the HI-LO study, which evaluated a multidisciplinary approach for treating hepatitis C in people who…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: Interferon Alfa Sensitivity in HIV/HCV Persons Before and After HIV Meds [Phase 4]
Phase 4 trial update evaluating interferon alfa sensitivity in HIV/Hepatitis C–coinfected individuals before and after initiation of HIV the…
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CLINICAL_TRIALS trial_result · 2016-11-29Clinical Trial Update: The Role of FGL2-FcgammaRIIB Inhibitory Pathway in Human Viral Hepatitis
This document describes a completed clinical trial evaluating the role of the FGL2-FcgammaRIIB inhibitory pathway in chronic hepatitis C inf…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Short Duration Versus Standard Response-Guided Therapy With Boceprevir Combined With PegIntron and Ribavirin in Previously Untreated Non-Cirrhotic Asian Participants With Chronic HCV Genotype 1 (MK-3034-107) [Phase 3]
Phase 3 trial comparing short-duration versus standard response-guided therapy using boceprevir in combination with pegylated interferon and…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Safety, Pharmacokinetics and Pharmacodynamics of Elbasvir (MK-8742) in Hepatitis C Infected Males (MK-8742-002) [Phase 1]
This Phase 1 study reports on the safety, pharmacokinetics, and pharmacodynamics of Elbasvir (MK-8742) in male participants infected with he…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Metformin Therapy in HCV Infection [Phase 4]
Phase 4 trial evaluating metformin therapy for chronic hepatitis C virus infection has completed; no results are provided in the snippet.
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Evaluating Three Grams Daily Valacyclovir in Patients With Chronic Hepatitis C and HSV-2 Infection (Phase I) [Phase 1]
Phase I trial evaluating three grams daily valacyclovir in patients with chronic hepatitis C and HSV-2 infection has completed, with results…
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CLINICAL_TRIALS trial_result · 2016-11-21Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Boceprevir Added to Standard of Care Therapy in Previously Treated Participants With Chronic Hepatitis C Genotype 1 and Cirrhosis (MK-3034-105) [Phase 4]
Phase 4 study evaluating boceprevir added to standard of care in previously treated chronic hepatitis C genotype 1 with cirrhosis; completed…
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CLINICAL_TRIALS trial_result · 2016-11-17Clinical Trial Update: Efficacy and Safety Study of Simeprevir in Combination With Sofosbuvir in Subjects With Chronic Genotype 4 Hepatitis C Virus Infection [Phase 3]
Phase 3 study evaluating the efficacy and safety of combining simeprevir with sofosbuvir in adults with chronic hepatitis C virus infection,…