Hepatitis C
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Pilot Study of HIV and Hepatitis B and C Screening in Surgery
This completed pilot trial evaluated screening for HIV, hepatitis B, and hepatitis C among surgical patients.
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: Toward Elimination of Hepatitis C Virus (HCV): A Pilot Study [Phase 4]
A Phase 4 pilot trial update aimed at eliminating hepatitis C virus. The study involves participants with Hepatitis C and heroin addiction, …
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir in Adults With Genotype 1a or Genotype 4 Chronic Hepatitis C Virus (HCV) Infection, With Severe Kidney Impairment or End Stage Kidney Disease [Phase 3]
A Phase 3 trial evaluating Ombitasvir/Paritaprevir/Ritonavir with or without Dasabuvir in adults with genotype 1a or 4 chronic hepatitis C a…
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CLINICAL_TRIALS trial_result · 2017-11-24Clinical Trial Update: A Study of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Sofosbuvir and Ribavirin in Direct-Acting Antiviral Agent Treatment-Experienced Adults With Chronic Hepatitis C Virus Infection [Phase 2]
Phase 2 trial update of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir with or without Sofosbuvir and Ribavirin in treatment-experienced ad…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: Study of ABT-333 in Both Healthy Volunteers and Hepatitis C Virus (HCV) + Genotype 1 Infected Subjects [Phase 1]
A Phase 1 trial of ABT-333 was conducted in healthy volunteers and Hepatitis C genotype 1 infected subjects; the study status is completed.
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: Anti-E1E2 (D32.10 Epitope-binding) Antibodies Status Prior Therapy Favors Direct-acting Antiviral Treatment Efficacy
A completed trial evaluating Anti-E1E2 (D32.10 epitope-binding) antibodies suggests prior therapy favors the efficacy of direct-acting antiv…
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: Side Effects After Direct-acting Antiviral Treatment
This clinical trial update summarizes the side effects observed after direct-acting antiviral therapy for chronic hepatitis C. The informati…
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CLINICAL_TRIALS trial_result · 2017-11-20Clinical Trial Update: Safety, Tolerability and PK Study of Single Doses of ABT-450 With and Without Ritonavir to Treat Hepatitis C Virus (HCV) Genotype 1 [Phase 1]
A Phase 1 safety, tolerability, and pharmacokinetic study evaluating single doses of ABT-450 with and without ritonavir in adults with Hepat…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination (FDC) for 12 or 24 Weeks in Kidney Transplant Recipients With Chronic HCV Infection [Phase 2]
Phase 2 trial evaluating safety and efficacy of ledipasvir/sofosbuvir fixed-dose combination for 12 or 24 weeks in kidney transplant recipie…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: A Multipart, Open-label Study to Evaluate the Safety and Efficacy of ABT-450/r/ABT-267 With and Without ABT-333 Coadministered With and Without Ribavirin in Adult With Genotype 1 or 4 Hepatitis C Virus (HCV) Infection and Human Immunodeficiency Virus, Type 1 Coinfection [Phase 2, Phase 3]
A multi-part open-label study evaluated ABT-450/r/ABT-267 with or without ABT-333 and ribavirin in adults with genotype 1 or 4 HCV, with or …
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Efficacy and Safety of Oral Regimens for the Treatment of Chronic HCV Infection [Phase 2]
Phase 2 clinical trial update evaluating oral regimens for chronic hepatitis C showed efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Safety and Efficacy of SOF/VEL/VOX FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis [Phase 3]
Phase 3 trial evaluating eight weeks of SOF/VEL/VOX fixed-dose combination or twelve weeks of SOF/VEL in adults with chronic genotype 3 hepa…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Drug Interaction Study Between Eltrombopag and Lopinavir/Ritonavir in Healthy Adult Subjects. [Phase 1]
Phase 1 trial evaluating potential drug interaction between eltrombopag and lopinavir/ritonavir in healthy adult subjects. The study status …
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Benefit of DAA Therapy in HCV Monoinfected and HIV-HCV Coinfected Patients With Mixed Cryoglobulinemia
This clinical trial update evaluates the benefit of direct-acting antiviral therapy in patients with chronic hepatitis C, including HIV coin…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Elbasvir/Grazoprevir (EBR/GZR) and Sofosbuvir (SOF) With and Without Ribavirin (RBV) in Cirrhotic Subjects With Chronic Hepatitis C Virus (HCV) Genotype 3 (GT3) Infection (MK-5172-083) [Phase 2]
Phase 2 trial assessing Elbasvir/Grazoprevir with and without Sofosbuvir and Ribavirin in cirrhotic Hepatitis C Genotype 3 patients; complet…
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CLINICAL_TRIALS trial_result · 2017-11-09Clinical Trial Update: Ombitasvir/ABT-450/Ritonavir and Dasabuvir With or Without Ribavirin in HCV Genotype 1-Infected Adults With Chronic Kidney Disease [Phase 3]
This completed Phase 3 trial tested an all-oral regimen of Ombitasvir/Paritaprevir/ritonavir with Dasabuvir, with or without Ribavirin, in a…
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy [Phase 3]
Phase 3 trial assessing safety and efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in adults with chronic hepatit…
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: First in Human Study of AL-704; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C [Phase 1]
First-in-human study of AL-704 includes single-dose food-effect in healthy volunteers and multiple-dose exposure in chronic hepatitis C; the…
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CLINICAL_TRIALS trial_result · 2017-11-07Clinical Trial Update: A Study to Evaluate Chronic Hepatitis C Infection in Adult Transplant Recipients [Phase 2]
Phase 2 study evaluating hepatitis C infection in adult transplant recipients has completed, and results have been posted by AbbVie.
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Safety and Efficacy of SOF/VEL/VOX FDC for 12 Weeks and SOF/VEL for 12 Weeks in DAA-Experienced Adults With Chronic HCV Infection Who Have Not Received an NS5A Inhibitor [Phase 3]
Phase 3 clinical trial evaluating 12-week regimens of SOF/VEL/VOX fixed-dose combination and SOF/VEL in adults with chronic hepatitis C who …
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: A Follow up Study Designed to Obtain Long Term Data on Participants Who Either Achieved a Sustained Virologic Response or Did Not Achieve a Sustained Virologic Response in an AbbVie Sponsored Hepatitis C Study [Phase 3]
This update reports long-term follow-up data from AbbVie’s hepatitis C trial participants, comparing outcomes based on whether they achieved…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Long-Term Extension Study of Miravirsen Among Participants With Genotype 1 Chronic Hepatitis C (CHC) Who Have Not Responded to Pegylated-Interferon Alpha Plus Ribavirin
A long-term extension study of Miravirsen in genotype 1 chronic hepatitis C patients who did not respond to pegylated interferon alfa plus r…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: First in Human Study of ALS-002200; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C Genotype 1 [Phase 1]
This trial update reports the first-in-human study of ALS-002200, including single-dose and food-effect evaluation in healthy volunteers and…
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CLINICAL_TRIALS trial_result · 2017-10-31Clinical Trial Update: First in Human Study of ALS-002158; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C Genotype 1 [Phase 1]
First-in-human study of ALS-002158 evaluated single-dose and food-effect in healthy volunteers and multiple-dose exposure in chronic hepatit…
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 in Treatment-Naïve and Treatment-Experienced, Non-Cirrhotic Asian Adults With Subgenotype 1b Chronic Hepatitis C Virus (HCV) Infection [Phase 3]
Phase 3 trial assessing AbbVie regimens ABT-450/r/ABT-267 with ABT-333 in treatment-naïve and treatment-experienced adults with chronic hepa…