Hepatitis C
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CLINICAL_TRIALS research · 2017-01-20Clinical Trial Update: Comparison of OraQuick HCV Rapid Antibody Test and Standard Serologic Screening for Hepatitis C: Validity, Acceptability and Impact on Linkage to Care [NA]
A terminated clinical trial comparing the OraQuick HCV Rapid Antibody Test with standard serologic screening to assess validity, acceptabili…
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CLINICAL_TRIALS research · 2016-11-15Clinical Trial Update: Differences in Evoked Intracellular Interferon Signaling Pathways Using Single Cell Phosphoprotein Profiling [Phase 1]
A Phase 1 study in Hepatitis C investigating differences in evoked intracellular interferon signaling pathways using single-cell phosphoprot…
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CLINICAL_TRIALS research · 2016-11-02Clinical Trial Update: An Observational Study To Assess Liver Fibrosis Stages in Patients With Chronic Hepatitis C Infection
An observational study was conducted to assess liver fibrosis stages in patients with chronic hepatitis C infection. The study has completed…
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CLINICAL_TRIALS research · 2016-11-01Clinical Trial Update: Efficacy Study to Evaluate the Effect of New Antiviral Drugs on HCV Infection. [Phase 4]
Phase 4 efficacy trial evaluating new antiviral drugs for chronic hepatitis C. The current status of the trial is UNKNOWN.
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CLINICAL_TRIALS research · 2016-09-29Clinical Trial Update: Direct Antiviral Agents for Hepatitis C Virus-associated Cryoglobulinaemia Vasculitis
This clinical trial update discusses the use of direct-acting antivirals to treat hepatitis C virus–associated cryoglobulinemic vasculitis; …
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CLINICAL_TRIALS research · 2016-09-26Clinical Trial Update: A Retrospective Study to Assess the Impact of the Use of Interferon in Patients With Chronic Hepatitis C (DECISION)
A retrospective study assessed the impact of interferon therapy in patients with chronic Hepatitis C; results were posted in 2016.
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CLINICAL_TRIALS research · 2016-09-21Clinical Trial Update: Immune Monitoring of Hepatitis C Under DAA Therapy
This document provides an update on an ongoing clinical trial evaluating immune monitoring in hepatitis C patients undergoing direct-acting …
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CLINICAL_TRIALS research · 2016-09-08Clinical Trial Update: HCV Care Pathway in Ile-de-France
An update on a hepatitis C care pathway trial in the Ile-de-France region sponsored by Assistance Publique - Hôpitaux de Paris; the current …
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CLINICAL_TRIALS research · 2016-07-26Clinical Trial Update: Association of Vitamin D Binding Protein Polymorphisms With Response to HCV Therapy
A completed clinical trial evaluated whether polymorphisms in vitamin D binding protein influence response to hepatitis C therapy in patient…
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CLINICAL_TRIALS research · 2016-06-07Clinical Trial Update: Mesenchymal Stem Cells Transplantation for Liver Cirrhosis Due to HCV Hepatitis [Phase 1, Phase 2]
This entry reports an ongoing Phase 1/Phase 2 clinical trial evaluating mesenchymal stem cell transplantation for liver cirrhosis caused by …
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CLINICAL_TRIALS research · 2016-04-22Clinical Trial Update: Rifaximin to Prevent Recurrent HCV-Related Fibrosis After Liver Transplant [Phase 2]
A Phase 2 trial from Columbia University evaluating rifaximin to prevent recurrent HCV-related liver fibrosis after liver transplant; curren…
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CLINICAL_TRIALS research · 2016-04-21Clinical Trial Update: Cognitive Impairments in Chronic Hepatitis C Patients and Potential Reversibility With New Agents (CICHepC) [Phase 4]
Phase 4 clinical trial investigating cognitive impairments in chronic hepatitis C patients and whether new agents can reverse them.
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CLINICAL_TRIALS research · 2016-04-08Clinical Trial Update: Study to Investigate Tolerability and Efficacy of MK5172 / MK8742 Without Ribavirin for 12 Weeks in Patients With Chronic HCV G1b Infection With Compensated Cirrhosis [Phase 3]
Phase 3 study assessing tolerability and efficacy of a ribavirin-free regimen of grazoprevir and elbasvir for 12 weeks in patients with chro…
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CLINICAL_TRIALS research · 2016-03-14Clinical Trial Update: Peripheral Blood Mononuclear Cell (PBMC) Gene Expression in HCV Genotype 1 Patients [Phase 4]
A Phase 4 study examining peripheral blood mononuclear cell gene expression in genotype 1 hepatitis C patients has been completed.
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CLINICAL_TRIALS research · 2016-02-25Clinical Trial Update: Study to Investigate the Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 and 4 HCV Infection With Autoimmune Disease [Phase 4]
Clinical trial update describing a Phase 4 study evaluating the efficacy and safety of the Ledipasvir/Sofosbuvir fixed-dose combination for …
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CLINICAL_TRIALS research · 2016-02-22Clinical Trial Update: A Study to Examine Patient Characteristics, Health Care Management and Health Outcomes of Hepatitis C Virus (HCV) Patients Treated With Simeprevir
This clinical trial update describes a study examining patient characteristics, health care management, and health outcomes of hepatitis C p…
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CLINICAL_TRIALS research · 2016-02-12Clinical Trial Update: Epidemiological Study to Evaluate the Management of Patients With Chronic Hepatitis C and Previous Treatment Failure
A completed epidemiological study evaluated how patients with chronic hepatitis C and prior treatment failure are managed.
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CLINICAL_TRIALS research · 2016-02-10Clinical Trial Update: The Effect of HIV Tat Protein on HCV Replication in an In-vitro Model System
An in-vitro study, sponsored by George Washington University, investigated whether HIV Tat protein influences Hepatitis C replication; the s…
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CLINICAL_TRIALS research · 2016-02-04Clinical Trial Update: Collection of Plasma and Serum Samples From Individuals Initiating Sofosbuvir for Chronic Hepatitis C for Testing
This trial update describes collection of plasma and serum samples from individuals initiating Sofosbuvir for Hepatitis C to support testing…
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CLINICAL_TRIALS research · 2016-02-02Clinical Trial Update: Use of Direct-acting Antiviral to Treat HCV Recurrence After Liver Transplantation (ANRSCO23CUPILT) Infection
A clinical trial update on using direct-acting antiviral therapy to treat hepatitis C recurrence after liver transplantation (ANRS CO23 CUPI…
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CLINICAL_TRIALS research · 2016-01-29Clinical Trial Update: A Multicenter Treatment Protocol of Daclatasvir (BMS-790052) in Combination With Sofosbuvir for the Treatment of Post-Liver Transplant Subjects With Chronic Hepatitis C
This document describes a multicenter treatment protocol evaluating the combination of daclatasvir and sofosbuvir in post-liver transplant p…
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CLINICAL_TRIALS research · 2015-12-09Clinical Trial Update: An Observational Study of Pegasys (Peginterferon Alfa-2a) Plus Copegus (Ribavirin) in Participants With Chronic Hepatitis C (CHC), Genotype 2, 3, 1 or 4, Undergoing Opioid Maintenance Therapy
An observational study evaluating peginterferon alfa-2a plus ribavirin in adults with chronic hepatitis C who are on opioid maintenance ther…
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CLINICAL_TRIALS research · 2015-11-10Clinical Trial Update: In Hepatitis C Patients Treated With Interferon and Ribavirin, Does Hepcidin Contribute to Treatment Induced Anaemia
A completed clinical study investigates whether hepcidin contributes to treatment-induced anaemia in hepatitis C patients treated with inter…
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CLINICAL_TRIALS research · 2015-11-04Clinical Trial Update: Pilot Study of Ezetimibe for Chronic Hepatitis C Virus (HCV) Infection [Phase 1]
A Phase 1 pilot trial assessing the safety and pharmacology of ezetimibe for chronic hepatitis C virus infection. The current trial status i…
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CLINICAL_TRIALS research · 2015-10-16Clinical Trial Update: ADHEPTA Study: Adherence Questionnaire in Hepatitis C
The ADHEPTA study evaluating an adherence questionnaire in people with chronic hepatitis C has completed. The study includes participants wi…