Hepatitis B
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: First in Human Study of ChAdOx1-HBV in Healthy Participants and Participants With Chronic hepB Infection [Phase 1]
First-in-human Phase 1 study of the ChAdOx1-HBV vaccine in healthy individuals and patients with chronic hepatitis B; results have been post…
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CLINICAL_TRIALS withdrawal · 2025-08-03Clinical Trial Update: A Clinical Trial to Evaluate the Efficacy and Safety of TQA3605 Tablets in Treatment-naive Chronic HBV-infected Subjects [Phase 2]
A Phase 2 trial evaluating TQA3605 tablets for treatment-naive chronic hepatitis B was withdrawn.
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: A Phase III Study to Evaluate the Efficacy and Safety of ZM-H1505R in Patients With CHB [Phase 3]
Phase III study to evaluate the efficacy and safety of ZM-H1505R in Chronic Hepatitis B. The trial is currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB) [Phase 2]
A Phase 2 clinical trial is evaluating sequential therapy with Daplusiran/Tomligisiran (DAP/TOM) followed by Bepirovirsen for chronic hepati…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Clinical Trials of the Hepatitis B Sandwich Combination Therapy for Treating Patients Infected With Hepatitis B Virus [NA]
A clinical trial entry for a Hepatitis B 'Sandwich' combination therapy for Hepatitis B infection and hepatocellular carcinoma, with the stu…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: A Study to Predict Recompensation in Patients With Decompensated Cirrhosis Using Spleen Stiffness and Simple Blood Tests
This clinical trial aims to predict recompensation in patients with decompensated cirrhosis using spleen stiffness measurements and simple b…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate [Phase 1, Phase 2]
This clinical trial update describes TherVacB, a heterologous protein prime/MVA boost therapeutic vaccine candidate for chronic hepatitis B,…
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Pan-Viral Screening and Linkage to Care Among GBMSM and Trans Women in Spain
A Spain-based clinical trial update describes pan-viral screening and linkage to care for HIV, Hepatitis B and C among GBMSM and trans women…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB) [Phase 2]
Phase 2 study evaluating the safety and efficacy of Selgantolimod-containing combination therapies for chronic hepatitis B has completed wit…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus Infection [Phase 1]
Phase 1 trial evaluating the safety, pharmacokinetics, and antiviral activity of ABI-4334 in adults with chronic hepatitis B has completed.
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CLINICAL_TRIALS research · 2025-07-22Clinical Trial Update: Real-world Study Evaluating the Long-term Outcomes of Pegylated Interferon α-2b Treatment in the Families With Clusters of HBV Infection and Unfavorable Prognosis - A Prospective, Controlled, Multicenter, Cohort Study
This clinical trial update describes a prospective, multicenter cohort study evaluating long-term outcomes of Pegylated Interferon alfa-2b i…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: B-Enhancement of HBV Vaccination in Persons Living With HIV (BEe-HIVe): Evaluation of HEPLISAV-B [Phase 3]
A Phase 3 trial (BEe-HIVe) evaluated HEPLISAV-B for hepatitis B vaccination in persons living with HIV. The study has completed and results …
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: A Study to Evaluate the Relative Bioavailability of Subcutaneous Bepirovirsen When Delivered From a Vial or Prefilled Syringe Fitted With a Safety Syringe Device in Healthy Adult Participants [Phase 1]
A Phase 1 study assessed the relative bioavailability of subcutaneous bepirovirsen when administered from a vial versus a prefilled syringe …
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation [NA]
Enrollment by invitation is ongoing for prophylactic entecavir to prevent hepatitis B reactivation in patients with past HBV infection under…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Towards a Functional Cure for HBV - The COMMIT Cohort Study
The COMMIT Cohort Study investigating functional cure approaches for hepatitis B in HIV/HBV coinfected individuals is currently active but n…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: HBV-Specific TCR-T Cell Therapy Combined With Nucleos(t)Ide Analogues in Chronic Hepatitis B Patients [Phase 1]
Phase 1 trial evaluating HBV-specific TCR-T cell therapy in combination with nucleos(t)ide analogues for chronic hepatitis B. The study is c…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Clinical Efficacy of Pegylated Interferon Alpha-2b Combined With Nucleos(t)Ide Analogues in the Treatment of Chronic Hepatitis B Patients [Phase 4]
Phase 4 clinical trial update evaluating pegylated interferon alfa-2b in combination with nucleos(t)ide analogues for chronic hepatitis B, w…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: The Impact of Treatment for Chronic Hepatitis B Virus on Non-clinical Harms
A clinical trial registry entry describing a study on the impact of treatment for chronic hepatitis B on non-clinical harms, which is curren…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Peg-interferon for Inactive Chronic Hepatitis B Carriers [Phase 2, Phase 3]
Clinical trial update reports completion of Phase 2/3 studies of pegylated interferon for inactive hepatitis B carriers.
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Halting Nucleoside Analogues in Chronic Hepatitis B [NA]
Clinical trial update regarding stopping nucleoside analogue therapy for chronic hepatitis B; the study is active but not recruiting.
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: "HBV unIversal vs Point-Of-Care-based Antiviral treatMent to Prevent Mother-to-child Transmission" [NA]
This clinical trial compares universal antiviral treatment for hepatitis B-infected pregnant women with a point-of-care-based approach to pr…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series [Phase 2, Phase 3]
Phase II/III trial update evaluating the immunogenicity, safety, and lot-to-lot consistency of LBVD, a fully liquid hexavalent DTaP-HepB-IPV…
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: The Safety and Efficacy of Sequential Treatment of Ropeginterferon Alfa-2b (P1101) and Anti-PD1 in Interferon-Naive Adults With Chronic Hepatitis B or D Infection [Phase 1]
This Phase 1 trial evaluated the safety and preliminary efficacy of sequential Ropeginterferon alfa-2b (P1101) followed by an anti-PD-1 agen…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Community Screening and Management of Hepatitis B, C and Delta in the Mongolian Population Living in France [NA]
A clinical trial update on community screening and management of hepatitis B, C, and D among the Mongolian population living in France; the …
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: A Study to Investigate the Safety and Efficacy of Undiluted Intravenous Infusion of I.V.-Hepabig Inj. [Phase 3]
A Phase 3 clinical trial evaluating the safety and efficacy of an undiluted intravenous infusion of I.V.-Hepabig Inj. for hepatitis B is cur…