Hepatitis B
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CLINICAL_TRIALS trial_result · 2010-07-15Clinical Trial Update: LT F-up Study 16-20 Yrs After Vaccine Dose of Hepatitis B With/Without HBIg in Newborns to HBeAg+ Mothers [Phase 4]
Long-term follow-up results (16-20 years) from a Hepatitis B vaccination study in newborns of HBeAg-positive mothers, comparing with and wit…
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CLINICAL_TRIALS research · 2010-07-07Clinical Trial Update: A Randomized Study Comparing Lamivudine Versus Adefovir Dipivoxil for Prevention of zHBV Reactivation in HBsAg Seropositive Patients Undergoing Cytotoxic Chemotherapy [NA]
A randomized study compares lamivudine versus adefovir dipivoxil to prevent hepatitis B reactivation in HBsAg-positive patients undergoing c…
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CLINICAL_TRIALS trial_result · 2010-07-05Clinical Trial Update: Evaluation of Antibody Persistence & Immune Memory in Subjects Vaccinated During Adolescence With Twinrix™ [Phase 4]
Phase 4 trial updating antibody persistence and immune memory after adolescence vaccination with Twinrix, focusing on Hepatitis A and B.
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CLINICAL_TRIALS trial_result · 2010-07-02Clinical Trial Update: Comparison of Entecavir to Adefovir in Chronic Hepatitis B Virus (HBV) Patients With Hepatic Decompensation [Phase 3]
Phase 3 trial comparing entecavir versus adefovir in adults with chronic hepatitis B and hepatic decompensation; study completed with result…
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CLINICAL_TRIALS research · 2010-07-01Clinical Trial Update: Systematic Review of Antiretroviral Treatments for Chronic Hepatitis B (CHB)
This document summarizes a systematic review of antiretroviral treatments for chronic hepatitis B.
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CLINICAL_TRIALS trial_result · 2010-06-29Clinical Trial Update: Pegasys Plus Entecavir Versus Entecavir Alone for Hepatitis Be Antigen-Positive Chronic Hepatitis B [Phase 4]
Phase 4 clinical trial comparing Pegasys (pegylated interferon alfa-2a) plus entecavir versus entecavir alone for Hepatitis Be antigen-posit…
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CLINICAL_TRIALS research · 2010-06-28Clinical Trial Update: Prophylaxis of Hepatitis B Virus Recurrence After Liver Transplantation [NA]
Clinical trial update focusing on prophylaxis to prevent hepatitis B virus recurrence after liver transplantation.
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CLINICAL_TRIALS trial_result · 2010-06-22Clinical Trial Update: 48 Weeks Combination Therapy for Patients With HBeAg-negative Chronic Hepatitis B Virus (HBV) Infection [Phase 3]
Phase 3 trial update reporting on 48 weeks of combination therapy for patients with HBeAg-negative chronic hepatitis B infection; the study …
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CLINICAL_TRIALS trial_result · 2010-06-22Clinical Trial Update: Influence of Hepatic Steatosis on the Therapeutic Effect of Entecavir in Chronic Hepatitis B Patients [Phase 4]
A Phase 4 clinical trial from Zhejiang University is investigating how hepatic steatosis influences the therapeutic effect of entecavir in c…
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CLINICAL_TRIALS trial_result · 2010-06-11Clinical Trial Update: Treatment With Peginterferon Alfa-2a (40 KD) of Chronic Hepatitis B Patients, Who Have Failed Anti-viral Treatment [Phase 4]
Phase 4 clinical trial evaluating peginterferon alfa-2a for chronic hepatitis B patients who failed antiviral therapy; the study status is c…
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CLINICAL_TRIALS trial_result · 2010-06-07Clinical Trial Update: HBV-specific T-cell Immunity in Individuals With HIV/HBV Co-infection
The update reports on HBV-specific T-cell immunity in individuals with HIV/HBV co-infection. The trial (NCT00476723) has completed.
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CLINICAL_TRIALS trial_result · 2010-06-02Clinical Trial Update: Hepatitis B Vaccination in HIV-infected Persons [Phase 4]
A Phase 4 clinical trial assessing Hepatitis B vaccination in HIV-infected persons has completed, reporting safety and immune response outco…
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CLINICAL_TRIALS trial_result · 2010-05-19Clinical Trial Update: A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Negative Chronic Hepatitis B [Phase 3]
A Phase 3 trial comparing tenofovir disoproxil fumarate (Viread) with adefovir dipivoxil in HBeAg-negative chronic hepatitis B has completed…
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CLINICAL_TRIALS trial_result · 2010-05-19Clinical Trial Update: A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Positive Chronic Hepatitis B [Phase 3]
Phase 3 trial comparing tenofovir disoproxil fumarate to adefovir dipivoxil in HBeAg-positive chronic hepatitis B was completed, with result…
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CLINICAL_TRIALS research · 2010-05-07Clinical Trial Update: Observe Change of Endotoxaemia and Related Mediators in Patients With Chronic Hepatitis B Virus (HBV) Infection
The trial evaluated changes in endotoxaemia and related mediators in patients with chronic hepatitis B infection; the study status is comple…
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CLINICAL_TRIALS trial_result · 2010-03-15Clinical Trial Update: The Effect of Viral Load on Intrahepatic Recurrence in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC) [NA]
A completed clinical trial investigating how viral load influences intrahepatic recurrence in HBV-related hepatocellular carcinoma, with res…
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FDA approval · 2010-03-03FDA Approved: PEGASYS — Supplemental Application (pharmaand GmbH)
FDA approved a supplemental application for PEGASYS (peginterferon alfa-2a) from pharmaand GmbH, approving an update to the biologics licens…
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CLINICAL_TRIALS trial_result · 2010-02-24Clinical Trial Update: Randomized Controlled Trial of Tenofovir in Patients of Reactivation of Hepatitis B Presenting as Acute on Chronic Liver Failure [Phase 4]
A Phase 4 randomized trial evaluated Tenofovir for hepatitis B reactivation presenting as acute-on-chronic liver failure, and the study has …
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CLINICAL_TRIALS research · 2010-02-09Clinical Trial Update: Health Promotion and Management for Hepatitis B Carriers [NA]
This clinical trial update describes a National Taiwan University Hospital study on health promotion and management for individuals with chr…
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CLINICAL_TRIALS trial_result · 2010-02-02Clinical Trial Update: A Phase II Dose Response Study in Japan in Chronic Hepatitis B [Phase 2]
A Phase II dose–response study in Japan for Chronic Hepatitis B sponsored by Bristol-Myers Squibb has completed.
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CLINICAL_TRIALS trial_result · 2010-02-02Clinical Trial Update: Continue Entecavir Rollover From China [Phase 3]
A Phase 3 trial of entecavir for chronic hepatitis B has completed, with a rollover from China reported by Bristol-Myers Squibb.
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CLINICAL_TRIALS trial_result · 2010-01-06Clinical Trial Update: Comparative Trial of Entecavir Versus Adefovir in the Treatment of Chronic Hepatitis B Infection [Phase 3]
Phase 3 trial comparing entecavir versus adefovir for chronic hepatitis B infection has completed with results posted.
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CLINICAL_TRIALS trial_result · 2009-12-23Clinical Trial Update: Safety and Antiviral Activity of TPV in HCV and/or HBV HIV Coinfected Patients TDM Randomised Pilot Evaluation [Phase 3]
Phase 3 trial evaluating the safety and antiviral activity of tipranavir (TPV) in HIV-infected patients coinfected with hepatitis C and/or h…
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CLINICAL_TRIALS trial_result · 2009-12-03Clinical Trial Update: Evaluation of Immune Memory to Twinrix or Comparator by Challenge Dose Administration 4 Years After Primary Vaccination [Phase 4]
Phase 4 trial evaluating immune memory to Twinrix or comparator after a challenge dose 4 years post-vaccination, with results previously pos…
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CLINICAL_TRIALS trial_result · 2009-11-23Clinical Trial Update: Arabinoxylan Rice Bran (MGN-3/Biobran) for the Treatment of Hepatocellular Carcinoma and Hepatitis B and C Infection [NA]
A completed clinical trial evaluated Arabinoxylan Rice Bran (MGN-3/Biobran) for hepatocellular carcinoma and hepatitis B/C infection.