Hepatitis B
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2015-12-30Clinical Trial Update: Compare Continuing Lamivudine Plus Adefovir or Adefovir Versus Switching to Entecavir Plus Adefovir in Patients With LAM-resistant Chronic Hepatitis B [Phase 4]
Phase 4 clinical trial update comparing continuing lamivudine plus adefovir versus switching to entecavir plus adefovir in lamivudine-resist…
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CLINICAL_TRIALS trial_result · 2015-12-07Clinical Trial Update: An Observational Study of Peginterferon Alfa-2a (PEGASYS®) in Patients With HBeAg Positive or HBeAg Negative Chronic Hepatitis B
This clinical trial update reports results from an observational study of peginterferon alfa-2a (PEGASYS) in patients with chronic hepatitis…
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CLINICAL_TRIALS research · 2015-12-03Clinical Trial Update: Combined Therapy With Peginterferon Alfa-2a With NA in NA-treated HBeAg Positive Patients [Phase 4]
This entry describes a Phase 4 clinical trial update of a combination therapy with peginterferon alfa-2a and a nucleoside analogue in HBeAg-…
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CLINICAL_TRIALS trial_result · 2015-12-02Clinical Trial Update: Lamivudine Therapy in Patients With Prior Entecavir Treatment and Undetectable Viral Load [NA]
A clinical trial update reports on lamivudine therapy in chronic hepatitis B patients previously treated with entecavir and with undetectabl…
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CLINICAL_TRIALS research · 2015-11-26Clinical Trial Update: A Clinical Trial on Hepatitis B Vaccine Activated-Dendritic Cells Combined With Anti-HBV Drugs in CHB [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating an activated-dendritic cell–based Hepatitis B vaccine in combination with anti-HBV drugs for chroni…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Adefovir or Entecavir in Patients With HBeAg-Positive Chronic Hepatitis B [Phase 4]
Phase 4 clinical trial evaluating PEGASYS (peginterferon alfa-2a) in combination with adefovir or entecavir for HBeAg-positive chronic hepat…
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CLINICAL_TRIALS withdrawal · 2015-11-18Clinical Trial Update: Evaluation of the Long-term Hepatitis A and B Antibody Persistence in Healthy Adult Subjects, Primed 16 to 20 Years Earlier With GSK Biologicals' Combined Hepatitis A and B Vaccine, Twinrix® (SB208127) in Study HAB-084 (208127/084) [Phase 4]
This Phase 4 study evaluating long-term hepatitis A and B antibody persistence in healthy adults previously primed with Twinrix has been wit…
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FDA approval · 2015-11-12FDA Approved: ENTECAVIR — Original Application (AvKARE)
FDA approved AvKARE's original application for entecavir (generic) for chronic hepatitis B.
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CLINICAL_TRIALS trial_result · 2015-11-11Clinical Trial Update: Hepatic Safety of Currently Used Antiretroviral Regimens in Patients With Chronic Hepatitis Under Real Life Conditions
This clinical trial update assesses the hepatic safety of currently used antiretroviral regimens in patients with chronic hepatitis and HIV …
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CLINICAL_TRIALS research · 2015-11-06Clinical Trial Update: Knowledge and Practice of Chinese Medical Specialists Regarding Chronic Hepatitis B Virus Infection
A completed clinical trial evaluating knowledge and practice of Chinese medical specialists regarding chronic hepatitis B virus infection.
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CLINICAL_TRIALS trial_result · 2015-11-06Clinical Trial Update: Prospective Study In Noninvasive Evaluation of Hepatic Fibrosis in Chronic Hepatitis B
A prospective study evaluating noninvasive methods to evaluate liver fibrosis in patients with chronic hepatitis B has completed.
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CLINICAL_TRIALS other · 2015-10-28Clinical Trial Update: Switch or Sequential Combination Therapy of Peginterferon in Hepatitis B Patients With Longterm Entecavir Therapy
A clinical trial update on switching or sequential Peginterferon therapy in chronic hepatitis B patients who are on long-term entecavir.
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen [Phase 2]
A Phase 2 dose-ranging study of pegylated interferon lambda in HBeAg-positive hepatitis B patients has completed.
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CLINICAL_TRIALS trial_result · 2015-10-07Clinical Trial Update: Study of an Investigational Vaccine in Healthy Infants in Taiwan (V441-001)(COMPLETED) [Phase 3]
Phase 3 trial of an investigational V441-001 vaccine in healthy infants in Taiwan has completed, targeting diphtheria, tetanus, pertussis, h…
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: Validity of Elastography During Pregnancy
A clinical trial evaluating the validity of elastography during pregnancy has been suspended, affecting pregnant women with hepatitis B.
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Evaluating Blood Glucose Levels During Infusion With HepaGam B (HBIG) in Post-liver Transplant Patients [Phase 4]
Phase 4 trial evaluating blood glucose during infusion with HepaGam B in hepatitis B patients after liver transplant. Results have been post…
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Study of DTaP-IPV-Hep B-PRP~T Combined Vaccine in Indian Infants Previously Given a Dose of Hepatitis B Vaccine at Birth [Phase 3]
Phase 3 trial of the DTaP-IPV-HepB-PRP-T pentavalent vaccine in Indian infants completed; results were posted in 2015.
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CLINICAL_TRIALS research · 2015-09-25Clinical Trial Update: An Exploratory Study of RGT Strategy on Optimal NUC-experienced Patients [Phase 4]
Clinical trial update describing an exploratory Phase 4 study of an RGT strategy in nucleoside analogue–experienced patients with chronic he…
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CLINICAL_TRIALS trial_result · 2015-09-23Clinical Trial Update: Induction of Fibrosis Regression on Patients With Chronic Hepatitis B Infection [Phase 4]
A Phase 4 trial evaluating induction of fibrosis regression in patients with chronic hepatitis B and liver fibrosis has been terminated.
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CLINICAL_TRIALS trial_result · 2015-09-14Clinical Trial Update: Identification of Specific Modulation Frequencies in Hepatitis B Carriers With and Without Hepatocellular Carcinoma [NA]
This document reports a completed clinical trial evaluating whether specific modulation frequencies differentiate Hepatitis B carriers with …
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Efficacy & Safety of Tenofovir Disoproxil Fumarate (TDF) Plus Peginterferon α-2a (Peg-IFN) Versus TDF or Peg-IFN Monotherapy in Chronic Hepatitis B [Phase 4]
This Phase 4 trial evaluated whether combining Tenofovir disoproxil fumarate with peginterferon alfa-2a improves efficacy and safety versus …
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CLINICAL_TRIALS trial_result · 2015-09-03Clinical Trial Update: Activation of Hepatitis B Virus (HBV) in Hepatitis B Surface Antigen (HBsAg) - Negative But Hepatitis B Core Antibody (Anti-HBc) - Positive Patients
This completed clinical trial investigates activation of hepatitis B virus in patients who are HBsAg-negative but Anti-HBc-positive, indicat…
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CLINICAL_TRIALS withdrawal · 2015-09-01Clinical Trial Update: Entecavir Plus Adefovir in Lamivudine-Resistant Patients [Phase 4]
A Phase 4 trial evaluating the combination of entecavir and adefovir for lamivudine-resistant chronic hepatitis B has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-08-31Clinical Trial Update: Efficacy and Safety of Peginterferon Alfa-2b in HBeAg Positive Chronic Hepatitis B [Phase 3]
Phase 3 trial evaluating the efficacy and safety of Peginterferon alfa-2b in HBeAg-positive chronic hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2015-08-27Clinical Trial Update: This Study Aims to Determine the Long-term Persistence of Antibodies Against Hepatitis B and to Evaluate the Immunogenicity and Safety of Hepatitis B Vaccine in Adolescents Vaccinated in Infancy With Infanrix™ Hexa [Phase 4]
This Phase 4 trial update assesses long-term persistence of antibodies against hepatitis B and evaluates the immunogenicity and safety of In…