Hepatitis B

• CLINICAL_TRIALS trial_result · 2016-11-28
  Clinical Trial Update: Increasing Hepatitis B Screening Among Korean Church Attendees [Phase 3]

  A Phase 3 clinical trial aimed at increasing Hepatitis B screening among Korean church attendees has completed.

• CLINICAL_TRIALS research · 2016-11-25
  Clinical Trial Update: Peginterferon Alfa-2b Treatment in HBeAg(+) Chronic Hepatitis b Patients Based on Interferon Gene Mutation and Receptor Detection [Phase 4]

  Phase 4 clinical trial evaluating peginterferon alfa-2b for HBeAg-positive chronic hepatitis B, examining the impact of interferon gene muta…

• CLINICAL_TRIALS trial_result · 2016-11-22
  Clinical Trial Update: The Safety and Dose-range Study of Metacavir Enteric-coated Capsules in Patients With Chronic Hepatitis B [Phase 2]

  This document provides a status update on a Phase 2 safety and dose-range study of Metacavir Enteric-coated Capsules in patients with Chroni…

• FDA approval · 2016-11-21
  FDA Approved: LAMIVUDINE — Original Application (Rising Pharma Holdings, Inc.)

  FDA approved the original generic application for lamivudine from Rising Pharma Holdings, Inc., making a generic option available for HIV-1 …

• CLINICAL_TRIALS trial_result · 2016-11-11
  Clinical Trial Update: Effect of Cyanobacteria Patients With Chronic Hepatitis B Surface Antigen Quantitative Concentration [NA]

  This clinical trial evaluates whether cyanobacteria affect the quantitative concentration of hepatitis B surface antigen (HBsAg) in adults w…

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• FDA approval · 2016-11-10
  FDA Approved: VEMLIDY — Original Application (Gilead Sciences, Inc.)

  FDA granted original approval to Vemlidy (tenofovir alafenamide) from Gilead Sciences for the treatment of chronic hepatitis B virus infecti…

• CLINICAL_TRIALS trial_result · 2016-11-09
  Clinical Trial Update: Tenofovir Disoproxil Fumarate vs. Entecavir in Chronic Hepatitis B Patients With Partial Virologic Response to Entecavir [Phase 4]

  A Phase 4 trial comparing tenofovir disoproxil fumarate with entecavir in chronic hepatitis B patients who had a partial virologic response …

• CLINICAL_TRIALS trial_result · 2016-11-07
  Clinical Trial Update: Effect of RO6871765 and RO7011785 on Immune Response With the Stimulation of Peripheral Blood Mononuclear Cells (PBMCs) in Chinese Healthy Volunteers and Chronic Hepatitis B Patients

  This clinical trial update describes the immune response effects of Roche investigational compounds RO6871765 and RO7011785 on stimulation o…

• CLINICAL_TRIALS trial_result · 2016-11-04
  Clinical Trial Update: Immunogenicity and Safety of a DTPa-HBV-IPV/Hib Vaccine Given at 2, 3 and 4 Months of Age [Phase 2]

  Phase 2 trial update evaluating the immunogenicity and safety of a pentavalent DTPa-HBV-IPV/Hib vaccine given at 2, 3, and 4 months of age.

• CLINICAL_TRIALS trial_result · 2016-11-03
  Clinical Trial Update: A Study of Pegylated Interferon Alfa-2a and Lamivudine in Patients With HBeAg-Negative Chronic Hepatitis B Virus (HBV) [Phase 3]

  Phase 3 study evaluating a combination of pegylated interferon alfa-2a and lamivudine in patients with HBeAg-negative chronic hepatitis B; r…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: Analysis of HBV-Specific Immune Response in Patients With HBeAg Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a (40KD)) - Immunology Sub-Study of ML18253 [Phase 3]

  This update analyzes HBV-specific immune responses in HBeAg-negative chronic hepatitis B patients treated with Pegasys (peginterferon alfa-2…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Peginterferon Alfa-2a [PEGASYS] in Patients With Chronic Hepatitis B Who Are HBeAg Positive [Phase 4]

  This document reports the completion of a Phase 4 trial studying pegylated interferon alfa-2a (Pegasys) in HBeAg-positive chronic hepatitis …

• CLINICAL_TRIALS research · 2016-11-02
  Clinical Trial Update: A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis B

  This is a completed retrospective biomarker study using stored samples from patients with chronic hepatitis B, sponsored by Hoffmann-La Roch…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: ADVANCE Study: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) + Adefovir Dipivoxil in Patients With Hbe(-) Chronic Hepatitis B [Phase 3]

  The ADVANCE Phase 3 trial evaluating PEGASYS (peginterferon alfa-2a) plus adefovir dipivoxil in patients with HBeAg-negative chronic hepatit…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis B Who Have Failed Antiviral Treatment With Nucleoside (Nucleotide) Analogues

  An observational study evaluating Pegasys (peginterferon alfa-2a) in patients with chronic hepatitis B who failed nucleoside analogue therap…

• CLINICAL_TRIALS research · 2016-11-02
  Clinical Trial Update: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HbeAg-negative Chronic Hepatitis B (Perseas)

  An observational study evaluating peginterferon alfa-2a (Pegasys) in patients with HBeAg-negative chronic hepatitis B has completed.

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Entecavir in Treatment-Naive Patients With HBeAg-Positive Chronic Hepatitis B. [Phase 4]

  Phase 4 study evaluating PEGASYS (peginterferon alfa-2a) plus entecavir in treatment-naive, HBeAg-positive chronic hepatitis B patients. The…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of PEGASYS (Peginterferon Alfa-2a [40KD]) in Patients With Hepatitis B e Antigen (HBeAg)-Negative Chronic Hepatitis B Virus (HBV) [Phase 4]

  Phase 4 clinical trial update shows PEGASYS (pegylated interferon alfa-2a) in patients with HBeAg-negative chronic hepatitis B has completed…

• CLINICAL_TRIALS trial_result · 2016-11-02
  Clinical Trial Update: A Study of Peginterferon Alfa-2a (Pegasys) in Participants With Hepatitis B E-Antigen (HBeAg)-Positive Chronic Hepatitis B Virus (HBV) [Phase 4]

  This Phase 4 trial evaluated peginterferon alfa-2a (Pegasys) in HBeAg-positive chronic hepatitis B patients and has completed.

• CLINICAL_TRIALS research · 2016-11-02
  Clinical Trial Update: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Positive or HBeAg-Negative Chronic Hepatitis B

  A completed observational study evaluated peginterferon alfa-2a (Pegasys) in patients with chronic hepatitis B, including both HBeAg-positiv…

• CLINICAL_TRIALS research · 2016-11-02
  Clinical Trial Update: A Follow-Up Study of Patients With HBeAg Positive Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML22265

  This clinical trial update reports follow-up data for patients with HBeAg-positive chronic hepatitis B treated with Pegasys (peginterferon a…

• CLINICAL_TRIALS trial_result · 2016-10-28
  Clinical Trial Update: Persistence of Hepatitis B Antibody Levels & Immune Response to a Hepatitis B Vaccine Challenge [Phase 4]

  Phase 4 study evaluating how long Hepatitis B antibodies persist and the immune response after a Hepatitis B vaccine challenge; study has co…

• CLINICAL_TRIALS trial_result · 2016-10-28
  Clinical Trial Update: TDF VS LAM + ADV in LAM + ADV Treated LAM-resistant CHB Patients With Undetectable Hepatitis B Virus DNA [Phase 4]

  A Phase 4 trial compares tenofovir disoproxil fumarate (TDF) with lamivudine plus adefovir in lamivudine- and adefovir-treated chronic hepat…

• CLINICAL_TRIALS trial_result · 2016-10-24
  Clinical Trial Update: A Study of Peginterferon Alfa-2a (40KD) (PEGASYS®) in Participants With Hepatitis B Envelope Antigen (HBeAg) - Positive Chronic Hepatitis B [Phase 4]

  Phase 4 study update on peginterferon alfa-2a (PEGASYS) in participants with HBeAg-positive chronic hepatitis B; the trial completed with re…

• CLINICAL_TRIALS trial_result · 2016-10-21
  Clinical Trial Update: The Effect of Alendronate on the Immune Response to Hepatitis B Vaccine in Healthy Adults [Phase 1]

  Phase 1 study examining whether alendronate affects the immune response to the Hepatitis B vaccine in healthy adults has completed.