Hepatitis B
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-09-19Clinical Trial Update: Study to Evaluate the Antiviral Efficacy, Safety and Tolerability of Tenofovir Disoproxil Fumarate Versus Placebo in Pediatric Participants With Chronic Hepatitis B Infection [Phase 3]
Phase 3 trial in pediatric patients compares tenofovir disoproxil fumarate to placebo for chronic hepatitis B; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-09-19Clinical Trial Update: Myrcludex B vs Entecavir in Patients With HBeAg Negative Chronic Hepatitis B [Phase 1, Phase 2]
Clinical trial comparing Myrcludex B to Entecavir in HBeAg-negative chronic hepatitis B has completed phases 1 and 2 with posted results.
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CLINICAL_TRIALS trial_result · 2018-09-17Clinical Trial Update: Response to GSK Biologicals' Tritanrix-HepB/Hib-MenAC Vacc (4th Dose) at 15-24m & Mencevax ACWY at 24-30m [Phase 3]
Phase 3 trial update of Tritanrix-HepB/Hib-MenAC and Mencevax ACWY vaccines with completed status and results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-29Clinical Trial Update: The Safety of Anti-viral Therapy in Preventing HBV MTCT in Pregnant Women After Discontinuation [Phase 4]
Phase 4 trial assessing safety of anti-viral therapy to prevent mother-to-child transmission of hepatitis B after discontinuation in pregnan…
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: Study to Assess Efficacy of Besifovir and L-carnitine in Chronic Hepatitis B Patients With Nonalcoholic Fatty Liver [Phase 4]
Clinical trial update for a Phase 4 study evaluating Besifovir and L-carnitine in hepatitis B patients with nonalcoholic fatty liver disease…
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CLINICAL_TRIALS trial_result · 2018-08-15Clinical Trial Update: Safety Study of a Vaccine Against Meningitis in Infants ( 2,4 & 6 Months Age) After a Birth Dose of Hepatitis B. [Phase 3]
Phase 3 safety trial update for a meningitis vaccine in infants following birth dose of Hepatitis B, completed.
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CLINICAL_TRIALS trial_result · 2018-08-15Clinical Trial Update: Safety Study of a Vaccine Against Meningitis in Infants (2,4 & 6 Months Age) After a Birth Dose of Hepatitis B. [Phase 3]
Phase 3 safety study evaluating a vaccine against meningitis in infants following a birth dose of hepatitis B; the trial is completed.
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CLINICAL_TRIALS trial_result · 2018-08-03Clinical Trial Update: Long-term Persistence of Immunity to Hepatitis B in Adults Vaccinated With GlaxoSmithKline (GSK) Biologicals' Hepatitis B Vaccine (HBV), Engerix-B [Phase 4]
Phase 4 trial assessing long-term persistence of immunity to hepatitis B in adults vaccinated with Engerix-B (HBV) by GSK; results posted in…
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CLINICAL_TRIALS trial_result · 2018-08-01Clinical Trial Update: Study to Determine the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals; Infanrix Hexa at 2, 4 and 6 Months of Age in Healthy Infants [Phase 3]
A Phase 3 trial assessing immunogenicity and safety of GSK Infanrix Hexa given at 2, 4, and 6 months in healthy infants; study completed wit…
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CLINICAL_TRIALS trial_result · 2018-08-01Clinical Trial Update: First Time in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of GSK3389404 in Healthy Subjects [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics of GSK3389404 in healthy subjects completed, with results posted.
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CLINICAL_TRIALS trial_result · 2018-08-01Clinical Trial Update: Collection of Samples for the Clinical Evaluation of the Aptima HBV (Hepatitis B Virus) Quant (Quantification) Assay
This clinical trial update describes the collection of samples for evaluating the Aptima HBV Quant assay. The study is reported as completed…
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CLINICAL_TRIALS trial_result · 2018-07-30Clinical Trial Update: Study of Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection
This clinical trial update reports the results of a study evaluating entecavir in patients with chronic hepatitis B. The results were posted…
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Optimized Treatment and Regression of HBV-induced Liver Fibrosis [Phase 4]
A Phase 4 clinical trial completed that reports optimized treatment associated with regression of HBV-induced liver fibrosis.
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Optimized Treatment and Regression of HBV-induced Early Cirrhosis [Phase 4]
Phase 4 trial update reports regression of HBV-related early liver cirrhosis with an optimized treatment approach.
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: Drug Drug Interaction Study for EYP001 With Entecavir [Phase 1]
Phase 1 drug-drug interaction study of EYP001 with Entecavir has completed. The study investigates potential interactions for chronic hepati…
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CLINICAL_TRIALS withdrawal · 2018-07-24Clinical Trial Update: A Nationwide Epidemiological, Educational Support Program for Improving Treatment Adherence in Patients With HBV
The study evaluating a nationwide epidemiological and educational support program to improve hepatitis B treatment adherence has been withdr…
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CLINICAL_TRIALS research · 2018-07-24Clinical Trial Update: Tenofovir Combination or Mono-therapy for MDR CHB
Clinical trial update evaluating tenofovir, either in combination therapy or as monotherapy, for multidrug-resistant chronic hepatitis B; th…
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CLINICAL_TRIALS trial_result · 2018-07-18Clinical Trial Update: Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases
This completed pediatric trial from Baylor College of Medicine evaluated non-invasive biomarkers to detect liver fibrosis in children with v…
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: A Korean Cohort Study of TDF Rescue Therapy for Difficult-to-treat CHB Patients: a Comparison Between TDF Monotherapy and TDF-based Combination Therapy
A completed Korean cohort study evaluated tenofovir disoproxil fumarate rescue therapy in difficult-to-treat chronic hepatitis B, comparing …
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CLINICAL_TRIALS research · 2018-07-17Clinical Trial Update: An Observational Study on Evaluating the Efficacy and Safety of Preemptive Antiviral Therapy With Tenofovir in HBsAg-positive Patients With Diffuse Large B-cell Lymphoma Receiving Rituximab-CHOP Chemotherapy (SPEED Study)
An observational study sponsored by Yonsei University evaluating whether preemptive antiviral therapy with Tenofovir is effective and safe f…
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CLINICAL_TRIALS research · 2018-07-16Clinical Trial Update: A Study to Investigate the Safety, Efficacy and Pharmacokinetic Profile of Multiple Doses of QL-007 in Chronic Hepatitis B Patients [Phase 1]
Phase 1 clinical trial evaluating safety, efficacy and pharmacokinetics of multiple doses of the investigational drug QL-007 in patients wit…
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CLINICAL_TRIALS research · 2018-07-16Clinical Trial Update: Study on Gut Microbiota in Chronic HBV Infected Patients
This is an update on a clinical trial studying gut microbiota in individuals with chronic hepatitis B infection, including a healthy control…
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Clinical Performance Evaluation of DxN HBV Assay
A terminated clinical performance evaluation study of the DxN HBV Assay for Hepatitis B, assessing its diagnostic performance.
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CLINICAL_TRIALS trial_result · 2018-07-06Clinical Trial Update: Phase 1b/2a Study of ABI-H0731 in Patients With Chronic Hepatitis B [Phase 1, Phase 2]
This clinical trial update reports the completion of a Phase 1b/2a study of ABI-H0731 in patients with chronic hepatitis B.
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FDA approval · 2018-07-06FDA Approved: ADEFOVIR DIPIVOXIL — Original Application (Apotex Corp.)
FDA approved Apotex's original application (ANDA) for Adefovir Dipivoxil, a generic antiviral for chronic hepatitis B infection.