Hepatitis B
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: Clinical Study to Evaluate the Efficacy and Safety of DA-2803 in Chronic Hepatitis B Patients [Phase 4]
The clinical trial update states that the Phase 4 study of DA-2803 in chronic hepatitis B has completed. No efficacy or safety results are d…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: A Study to Evaluate the Antiviral Activity and Safety of HH-003 in Chronic Hepatitis B Subjects With Low-level Viremia [Phase 2]
Phase 2 trial evaluating antiviral activity and safety of HH-003 in adults with chronic hepatitis B infection and low-level viremia has comp…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: A Study of LW231 to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Volunteers and Participants With Chronic Hepatitis B Virus Infection [Phase 1]
A Phase 1 trial evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of LW231 in healthy volunteers and participants with…
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CLINICAL_TRIALS withdrawal · 2024-10-15Clinical Trial Update: Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection [Phase 1]
The Phase 1 trial of IMC-I109V for non-cirrhotic, HBeAg-negative chronic hepatitis B infection has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis [Phase 1, Phase 2]
Completed Phase 1/2 clinical trial evaluating the safety and effectiveness of PRI-724 in patients with cirrhosis due to Hepatitis C or Hepat…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Effectiveness of Antiviral Treatment in Cirrhotic Patients with Low-level Hepatitis B Virus DNA Levels [Phase 4]
A Phase 4 clinical trial is evaluating the effectiveness of antiviral treatment in patients with chronic hepatitis B–related cirrhosis who h…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infection [Phase 1]
Phase 1 trial update for VIR-3434 in healthy volunteers and patients with chronic hepatitis B; results have been posted.
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: Treatment Prioritisation and Cost-Effectiveness Analysis for HBV Cure - Real-World Evidence from a Territory-Wide Cohort
A ClinicalTrials.gov entry describing a real-world evidence study from a territory-wide cohort to prioritise HBV treatment and assess cost-e…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: Long-Term Study of Liver Disease in People With Hepatitis B and/or Hepatitis C With or Without HIV Infection
This update reports the completed status of a long-term clinical trial evaluating liver disease in people with hepatitis B and/or hepatitis …
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Study to Evaluate the Immunogenicity of LR20062 Compared to Control When Administered Intramuscularly in Healthy Infants At 2, 4, 6 Months of Age [Phase 2]
Phase 2 trial to evaluate the immunogenicity of LR20062 versus control in healthy infants at 2, 4, and 6 months of age. The study targets pr…
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CLINICAL_TRIALS research · 2024-09-27Clinical Trial Update: Quantitative CT Imaging Parameters for Assessing Hepatic Steatosis in CHB
This clinical trial update outlines planned quantitative CT imaging parameters for assessing hepatic steatosis in patients with chronic hepa…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection [Phase 2]
Phase 2 study evaluating JNJ-73763989 with pegylated interferon alpha-2a, and a nucleos(t)ide analog, with or without JNJ-56136379, in treat…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Study of Safety and Tolerability of DCR HBVS [Phase 1]
Phase 1 study of DCR HBVS in chronic hepatitis B has completed, with safety and tolerability data reported.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Hepatitis Inequalities Study
This clinical trial, sponsored by the Chinese University of Hong Kong, investigates hepatitis-related inequalities in patients with chronic …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Decentralization of Hepatitis B Care in Sub-Saharan Africa: a Pilot Program in Ethiopia
A clinical trial update describing a pilot program to decentralize hepatitis B care in Sub-Saharan Africa, starting in Ethiopia. The aim is …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV [Phase 3]
This document reports a Phase 3 clinical trial evaluating the immunogenicity and safety of a hexavalent vaccine that contains a reduced-dose…
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CLINICAL_TRIALS other · 2024-09-19Clinical Trial Update: Metabolic Syndrome and Fatty Liver Disease Among Egyptian Patients with Chronic HBV
A clinical trial update from Assiut University describes a study evaluating metabolic syndrome and fatty liver disease in Egyptian patients …
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EMA approval · 2024-09-17EMA Authorised: Vemlidy (tenofovir alafenamide fumarate) — Gilead Sciences Ireland UC
The European Medicines Agency authorised Vemlidy (tenofovir alafenamide fumarate) for the treatment of hepatitis B. The decision date was 26…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: The Effects of Vitamin D and Calcium Supplementation to Parathyroid Hormone in CHB Patients Treated With TDF [Phase 4]
A Phase 4 clinical trial evaluating whether vitamin D and calcium supplementation modulates parathyroid hormone in patients with chronic hep…
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Current Situation of Health Care in Women With HBV or HCV Infection
This clinical trial update describes a study sponsored by Ruijin Hospital focusing on health care in women with hepatitis B or hepatitis C. …
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Liver Status and Presence of MASLD/MASH in Patients With Chronic Hepatitis B
This clinical trial update notes the completed study investigating liver status and the presence of MASLD/MASH in patients with chronic hepa…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland China [Phase 2]
A Phase 2 study of VIR-2218 for chronic hepatitis B in Mainland China has completed, with results posted.
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: A Clinical Trial to Evaluate the Efficacy and Safety of TQA3810 Tablets in Combination/Non Combination With Nucleoside (Acid) Analogues in Patients With Primary/Treated Chronic Hepatitis B [Phase 2]
A Phase 2 clinical trial to evaluate the efficacy and safety of TQA3810 tablets in combination with or without nucleoside (acid) analogue th…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: First-In-Human Study of ChAdOx1-HBV & MVA-HBV Vaccines (VTP-300) for Chronic HBV [Phase 1, Phase 2]
A first-in-human study of ChAdOx1-HBV and MVA-HBV vaccines (VTP-300) for chronic hepatitis B completed Phase 1/2, with results posted in Aug…
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CLINICAL_TRIALS research · 2024-08-13Clinical Trial Update: Improved Sensitivity Detection of Serum HBsAg and HBsAg Reversion
A clinical trial update describing an approach to improve detection sensitivity of hepatitis B surface antigen (HBsAg) and to study HBsAg re…