Hepatitis B
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: A Non-interventional Registry for Patients with Hepatitis B Virus Infection
This entry describes a non-interventional registry study sponsored by Hannover Medical School to collect observational data on patients with…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Non-Invasive Model for Fibrosis Regression in HBV Patients
An ongoing clinical trial in recruitment evaluating a non-invasive model for fibrosis regression in patients with chronic hepatitis B infect…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: The Effect of Hot Foot Bath on Sleep Quality and Fatigue [NA]
This clinical trial update from Uludag University examines whether a hot foot bath improves sleep quality and fatigue in people with Hepatit…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Radomised Phase II Study of MTL-CEBPA Plus Sorafenib or Sorafenib Alone [Phase 2]
Randomized Phase II trial comparing MTL-CEBPA plus Sorafenib to Sorafenib alone in hepatocellular carcinoma; the study includes patients wit…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Evaluation of Hepatitis B Virus (HBV) DNA Test As Point of Care Tool
A completed clinical trial evaluating the performance of a point-of-care HBV DNA test as a diagnostic tool for hepatitis B.
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Evaluation of The Safety, Efficacy and Pharmacokinetic Characteristics of GST-HG141 Tablets [Phase 2]
A Phase 2 trial evaluating the safety, efficacy, and pharmacokinetics of GST-HG141 Tablets for chronic hepatitis B has completed.
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: Non-interventional Study to Assess the Number of People With Untreated/Unknown HBV + HDV and HCV in South-East Austria
Non-interventional study in Southeast Austria to estimate the number of people with untreated or unknown hepatitis B, hepatitis C, and hepat…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: FibroTouch Non-invasive Evaluation of Liver Fibrosis and Cirrhosis
A completed clinical trial evaluating the FibroTouch non-invasive device for assessing liver fibrosis and cirrhosis has posted results. The …
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CLINICAL_TRIALS research · 2025-03-05Clinical Trial Update: A Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Study to Evaluate the Safety and Efficacy of GST-HG131 Tablets in Patients With Chronic Hepatitis B [Phase 2]
A Phase IIa randomized, double-blind, placebo-controlled trial is evaluating the safety and efficacy of GST-HG131 tablets in adults with chr…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: A Phase I, the Study to Evaluate the Safety, Immunogenicity and Efficacy of YS-HBV-002 [Phase 1]
A Phase I trial of YS-HBV-002 for chronic hepatitis B has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Site Settings [NA]
A completed trial evaluated the diagnostic performance of the iStatis HBsAg test at point-of-care settings, focusing on its sensitivity and …
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: A Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Sites [NA]
Completed clinical trial evaluating the sensitivity and specificity of the iStatis HBsAg Test at point-of-care sites for Hepatitis B infecti…
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CLINICAL_TRIALS other · 2025-02-17Clinical Trial Update: Replicor Compassionate Access Program
Replicor's compassionate access program for hepatitis B and hepatitis D, along with related liver diseases, is no longer available.
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: A Study Evaluating AHB-137 in Healthy Participants and Participants with Chronic Hepatitis B [Phase 1]
A Phase 1 trial evaluating AHB-137 in healthy participants and in individuals with chronic hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participants [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of a combination of JNJ-73763989, nucleos(t)ide analogs, and a PD-1 inhibitor in a…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: From Fungus to Virus, Investigating the Safety and Efficacy of Terbinafine in Chronic Hepatitis B Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety and efficacy of Terbinafine in patients with chronic hepatitis B and is currently recrui…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: National Cohort of Patients Co-infected With Hepatitis B and Delta Viruses
A clinical trial update describing a national cohort of patients co-infected with chronic hepatitis B and hepatitis D; the study is currentl…
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Study Evaluating the Safety, in Terms of HBV Virological Control At 96 Weeks, of 2 Antiviral Treatment Relief Strategies, in Patients Co-infected with the HIV-1 and HBV Viruses [Phase 2]
Phase 2 study evaluating two antiviral treatment relief strategies for safety and HBV virological control over 96 weeks in HIV/HBV co-infect…
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: To Evaluate the Efficacy and Safety of Tenofovir Alafenamide Conversion in Liver Transplant Patients [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of converting liver transplant patients with hepatitis B to tenofovir alafenamide …
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Study of AL-034 to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses in Healthy Participants [Phase 1]
AL-034 underwent a Phase 1 trial in healthy participants to assess safety, tolerability, and pharmacokinetics, with Hepatitis B listed as th…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Study of Orally Administered JNJ-440 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Doses Including Food Effect Evaluation; After Multi-Day Dosing in Healthy Participants; and After Multiple (Ascending) Doses in Participants With Chronic Hepatitis B [Phase 1]
Phase 1 study of the oral antiviral JNJ-440 to assess safety, tolerability, and pharmacokinetics after single ascending doses (with food eff…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: A Study of Orally Administered JNJ-56136379 to Evaluate Safety, Tolerability and Pharmacokinetics After Single Ascending Doses and One Multiple Dose Regimen in Healthy Participants (Part I), and After Multiple Dose Regimens in Participants With Chronic Hepatitis B (Part II) [Phase 1]
This document reports the completion of a Phase 1 trial of JNJ-56136379, evaluating safety, tolerability, and pharmacokinetics in healthy pa…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Single and Multiple Ascending Dose Study of JNJ-64457744 [Phase 1]
Phase 1 single- and multiple-ascending-dose study of JNJ-64457744 was terminated, including participants who were healthy and with chronic h…
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Research on Clinical Recovery and Maintenance Strategies for CHB [NA]
A clinical trial update indicates recruitment is ongoing for a study on recovery and maintenance strategies in chronic hepatitis B, includin…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Hepatitis B Vaccine Delivered Trans-dermally by MAP [Phase 1]
This is a Phase 1 clinical trial evaluating a trans-dermal Hepatitis B vaccine delivered via a MAP patch. Recruitment has not yet begun.