Hepatitis B
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CLINICAL_TRIALS trial_result · 2022-08-02Clinical Trial Update: Atorvastatin Use and Portal Hypertension in Patients With Hepatitis B Virus-related Liver Cirrhosis: A Randomized Controlled Trial [Phase 2]
A Phase 2 randomized trial evaluating atorvastatin use in patients with hepatitis B virus-related liver cirrhosis and portal hypertension.
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CLINICAL_TRIALS trial_result · 2022-07-26Clinical Trial Update: Effects of Pioglitazone and Evogliptin on Hepatic Fibrosis in Patients With Chronic Hepatitis B With Type 2 Diabetes [Phase 4]
Phase 4 trial exploring the effects of pioglitazone and evogliptin on hepatic fibrosis in patients with chronic hepatitis B and type 2 diabe…
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CLINICAL_TRIALS trial_result · 2022-07-25Clinical Trial Update: Safety and Immunogenicity of Recombinant Hepatitis B Vaccine Sci-B-Vac® Compared to Engerix-B® [Phase 3]
Phase 3 trial comparing Sci-B-Vac to Engerix-B for safety and immunogenicity in Hepatitis B was completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-07-20Clinical Trial Update: Demonstration Project on Health Care Worker Protection Against Hepatitis B in Kalulushi District [Phase 4]
Phase 4 demonstration project assessing health care worker protection against Hepatitis B in Kalulushi District has completed.
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CLINICAL_TRIALS trial_result · 2022-06-24Clinical Trial Update: A Bridging Study: Comparing Two Lots of Sci-B-Vac™ and Engerix-B in Healthy Adults [Phase 3]
Phase 3 bridging study comparing two lots of Sci-B-Vac and Engerix-B in healthy adults has completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-06-24Clinical Trial Update: A Study to Qualify an In-house Reference Standard Batch of Sci-B-Vac™ [Phase 4]
Phase 4 trial updating qualification of an in-house reference standard batch for Sci-B-Vac, with Hepatitis B as the indication.
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CLINICAL_TRIALS trial_result · 2022-06-23Clinical Trial Update: A Phase II Clinical Trial of Hydronidone Capsules(F351) in Patients With Liver Fibrosis Induced by HBV Chronic Hepatitis [Phase 2]
Phase II trial completed evaluating Hydronidone capsules (F351) for liver fibrosis due to chronic Hepatitis B infection.
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CLINICAL_TRIALS trial_result · 2022-06-09Clinical Trial Update: Evaluate the Efficacy and Safety to Tenofovir Disoproxil in Chronic Hepatitis B Patients [Phase 4]
Phase 4 trial update evaluating the efficacy and safety of Tenofovir Disoproxil in adults with chronic hepatitis B.
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CLINICAL_TRIALS trial_result · 2022-06-03Clinical Trial Update: Efficacy of Tenofovir Disoproxil on Mother-to-child Transmission of HBV in Tokombéré, Cameroon in Pregnant Women [Phase 4]
A Phase 4 clinical trial update evaluating the efficacy of Tenofovir Disoproxil in reducing mother-to-child transmission of hepatitis B viru…
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CLINICAL_TRIALS trial_result · 2022-05-19Clinical Trial Update: Antiviral Therapy for Patients With Chronic Hepatitis B Infection [Phase 2]
Phase 2 clinical trial update for an antiviral therapy in chronic hepatitis B infection.
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CLINICAL_TRIALS trial_result · 2022-05-18Clinical Trial Update: Intra-dermal With Topical Imiquimod Pretreatment Versus Intra-muscular Hepatitis B Vaccination in IBD Patients [Phase 2, Phase 3]
Phase 2/3 trial comparing intra-dermal imiquimod pretreatment with topical application versus intramuscular Hepatitis B vaccine in patients …
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CLINICAL_TRIALS trial_result · 2022-05-02Clinical Trial Update: Efficacy and Safety of Ricovir® in Maintaining Durability of Viral Response in Chronic Hepatitis B Patients Who Have Been Treated With Viread® and Have Undetectable HBV DNA in Serum [Phase 4]
Phase 4 trial update on Ricovir in maintaining viral suppression in chronic hepatitis B patients previously treated with Viread, completed.
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CLINICAL_TRIALS trial_result · 2022-04-06Clinical Trial Update: Anti-Hep B Antibodies at Age 9 to 10 Years After Hep B Vaccine at Birth and DTaP-IPV-Hep B-PRP-T Hexavalent Vaccine. [Phase 3]
Phase 3 trial update on anti-Hepatitis B antibodies in children aged 9–10 following birth Hep B vaccine and a hexavalent DTaP-IPV-Hep B-PRP-…
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CLINICAL_TRIALS trial_result · 2022-04-05Clinical Trial Update: Immunogenicity and Safety of Sanofi Pasteur's Combined Vaccine Given as a Three-Dose Primary Series at 2, 3,4 Months of Age and Followed by a Booster Dose Given at 16 to 17 Months of Age in Vietnamese Infants Who Previously Received a Dose of Hepatitis B Vaccine at Birth or Within 1 Week After Birth [Phase 3]
Phase 3 trial update evaluating the immunogenicity and safety of Sanofi Pasteur's combined vaccine given as a three-dose primary series in i…
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CLINICAL_TRIALS trial_result · 2022-04-05Clinical Trial Update: DTaP-IPV-HB-PRP-T Combined Vaccine as a Primary Series and a Second Year of Life Booster in HIV-Exposed Infected and Uninfected Infants [Phase 3]
Phase 3 clinical trial evaluating DTaP-IPV-HB-PRP-T as a primary series and a second-year booster in HIV-exposed infants (infected and uninf…
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CLINICAL_TRIALS trial_result · 2022-04-04Clinical Trial Update: Study to Evaluate the Safety and Antiviral Activity of Inarigivir Soproxil (Formerly: GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B (CHB) [Phase 2]
Phase 2 trial evaluating safety and antiviral activity of inarigivir soproxil plus tenofovir alafenamide in adults with chronic hepatitis B;…
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CLINICAL_TRIALS trial_result · 2022-04-01Clinical Trial Update: A phase4 Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis B [Phase 4]
Phase 4 trial evaluating safety and efficacy of switching from Tenofovir Disoproxil Fumarate to Tenofovir Disoproxil in chronic hepatitis B …
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CLINICAL_TRIALS trial_result · 2022-03-14Clinical Trial Update: ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC Discontinuation [Phase 2]
Phase 2 clinical trial exploring TLR8 stimulation followed by nucleos(t)ide analog discontinuation for chronic hepatitis B; status currently…
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: TDF Dose Adjustment VS. Switching to TAF in TDF-experienced CHB Patients With Renal Impairment [Phase 4]
A Phase 4 clinical trial comparing tenofovir disoproxil fumarate (TDF) dose adjustment versus switching to tenofovir alafenamide (TAF) in TD…
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CLINICAL_TRIALS trial_result · 2022-02-18Clinical Trial Update: Immunogenicity of Hepatitis B Vaccination Among Drug Users [Phase 4]
Phase 4 trial update on the immunogenicity of Hepatitis B vaccination among drug users; results posted.
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CLINICAL_TRIALS trial_result · 2022-02-14Clinical Trial Update: Immunogenicity of Hepatitis B Vaccination in Hemodialysis Patients [Phase 4]
Phase 4 trial update on the immunogenicity of Hepatitis B vaccination in patients on hemodialysis, with results posted.
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CLINICAL_TRIALS trial_result · 2022-02-14Clinical Trial Update: Efficacy and Safety Study of Tenofovir Disoproxil Fumarate (TDF) in Chinese Chronic Hepatitis B (CHB) Subjects With Advanced Fibrosis & Compensated Cirrhosis [Phase 4]
Phase 4 trial update on efficacy and safety of Tenofovir Disoproxil Fumarate in Chinese patients with chronic hepatitis B and advanced fibro…
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CLINICAL_TRIALS trial_result · 2022-02-11Clinical Trial Update: Non Inferiority Trial of Locally Manufactured 'Hepa-B' Vaccine in Bangladesh. [Phase 2, Phase 3]
A non-inferiority trial update for a locally manufactured Hepa-B vaccine conducted in Bangladesh; study phases include Phase 2 and Phase 3 a…
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CLINICAL_TRIALS trial_result · 2022-01-24Clinical Trial Update: Peginterferon Alpha-2b Therapy in Chronic Hepatitis Patients With Normal ALT Level and Low Viremia [Phase 1, Phase 2]
Clinical trial update for peginterferon alpha-2b in chronic hepatitis B patients with normal ALT and low viremia (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2022-01-05Clinical Trial Update: Preventing Mother-to-child Transmission of Hepatitis B Virus With Tenofovir Alafenamide (TAF) [Phase 4]
A Phase 4 clinical trial update evaluating tenofovir alafenamide (TAF) to prevent mother-to-child transmission of Hepatitis B virus.