Hepatitis B
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participants [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of a combination of JNJ-73763989, nucleos(t)ide analogs, and a PD-1 inhibitor in a…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Study of AL-034 to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses in Healthy Participants [Phase 1]
AL-034 underwent a Phase 1 trial in healthy participants to assess safety, tolerability, and pharmacokinetics, with Hepatitis B listed as th…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Study of Orally Administered JNJ-440 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Doses Including Food Effect Evaluation; After Multi-Day Dosing in Healthy Participants; and After Multiple (Ascending) Doses in Participants With Chronic Hepatitis B [Phase 1]
Phase 1 study of the oral antiviral JNJ-440 to assess safety, tolerability, and pharmacokinetics after single ascending doses (with food eff…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: A Single and Multiple Ascending Dose Study of JNJ-64457744 [Phase 1]
Phase 1 single- and multiple-ascending-dose study of JNJ-64457744 was terminated, including participants who were healthy and with chronic h…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: A Phase II Study of Hepalatide in Subjects With Chronic Hepatitis B [Phase 2]
The document reports the completion status of a Phase II study evaluating Hepalatide in adults with chronic hepatitis B.
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment [Phase 1]
Phase 1 pharmacokinetic study evaluating tipranavir/ritonavir, ribavirin, and pegylated interferon in subjects with mild hepatic impairment …
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: Cameroon Baptist Convention Health Board Chronic Hepatitis B Cohort Study
Clinical trial update indicating that the Cameroon Baptist Convention Health Board Chronic Hepatitis B Cohort Study sponsored by Mayo Clinic…
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CLINICAL_TRIALS trial_result · 2025-01-09Clinical Trial Update: Tenofovir Alafenamide Switching Therapy in Kidney or Liver Transplant Recipients With Chronic HBV Infection [Phase 4]
Phase 4 clinical trial update evaluating switching kidney or liver transplant recipients with chronic hepatitis B to Tenofovir alafenamide t…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: This is a Phase 1 Study in Which Healthy Volunteers and Participants with Chronic HBV Infection Will Receive HT-101 or Placebo and Will Be Assessed for Safety, Tolerability, Pharmacokinetics (PK), and Antiviral Activity [Phase 1]
A Phase 1 trial comparing HT-101 to placebo in healthy volunteers and adults with chronic hepatitis B to evaluate safety, tolerability, phar…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Hydronidone for the Treatment of Liver Fibrosis Associated with Chronic Viral Hepatitis B Phase 3 Trial. [Phase 3]
A Phase 3 trial evaluating Hydronidone for liver fibrosis associated with chronic hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Phase 1 Study of HT-102 Administered Subcustaneously in Healthy Participants and Patients with Chronic Hepatitis B for Safety, Tolerability, Pharmacokinetics (PK), and Antiviral Activity (only in Participants with Chronic HBV Infection) [Phase 1]
Phase 1 study of HT-102 administered subcutaneously in healthy participants and chronic hepatitis B patients to evaluate safety, tolerabilit…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B [Phase 2]
Phase 2 mechanistic study evaluating GSK3228836 with fine-needle aspiration in participants with chronic hepatitis B; the trial has complete…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Long-term Safety and Efficacy of Tenofovir Amibufenamide in Patients With CHB [Phase 4]
Long-term safety and efficacy data for Tenofovir Amibufenamide in chronic hepatitis B from a Phase 4 trial, currently active but not recruit…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Study of the Efficacy and Safety of HS-10234 in Patients With Chronic Hepatitis B Virus Infection [Phase 3]
This clinical trial update reports the completion of a Phase 3 study evaluating the efficacy and safety of HS-10234 in patients with chronic…
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines [Phase 4]
Phase 4 trial update evaluating whether tenofovir alafenamide reduces clinical events in chronic hepatitis B patients beyond current guideli…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: A Phase II Clinical Study of the Efficacy and Safety of HRS9950 Tablets in Chronic Hepatitis B Patients Who Are Virologically Suppressed on Nucleoside or Nucleotide Analogues (NAs) [Phase 2]
Phase II trial evaluating the efficacy and safety of HRS9950 tablets in chronic hepatitis B patients virologically suppressed on nucleoside …
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CLINICAL_TRIALS trial_result · 2024-12-02Clinical Trial Update: A Phase II Study of Subcutaneously Injected PD-L1 Antibody ASC22 in Chronic Hepatitis B Patients [Phase 2]
This document reports the completion of a Phase II clinical trial evaluating ASC22, a subcutaneously injected PD-L1 antibody, in patients wi…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating the safety of combining navitoclax with sorafenib tosylate in patients with relapsed or refractory solid tumors, in…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Prevention of Recurrent Hepatitis B After Liver Transplantation
This update reports the completion of a clinical trial evaluating strategies to prevent recurrent hepatitis B after liver transplantation, s…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: A Clinical Study of TQA3605 Tablets Monotherapy or in Combination With Nucleoside (Acid) Analogues in Treatment Naive and Treated Patients With Chronic Hepatitis B [Phase 1, Phase 2]
A Phase 1/2 clinical study of TQA3605 tablets as monotherapy or in combination with nucleoside analogues for treatment-naive and previously …
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: TAF to Prevent HBV Reactivation in Cancer Patients [Phase 4]
Phase 4 clinical trial investigating tenofovir alafenamide (TAF) to prevent hepatitis B reactivation in cancer patients; the study is curren…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Safety, Tolerability, Pharmacokinetics(PK), Pharmacodynamics(PD) and Food Effect of HRS9950 in Healthy and CHB Subjects [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics/pharmacodynamics, and the effect of food on HRS9950 in healthy volunteers an…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected Participants [Phase 1]
This Phase 1 trial evaluated the safety, tolerability, pharmacokinetics and pharmacodynamics of RO7049389 in healthy volunteers and chronic …
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: A Clinical Trial of TQ-A3334 Tablet After Multiple Administration in Adult Subjects [Phase 1]
A Phase 1 study evaluating multiple-dose administration of TQ-A3334 tablets in adult subjects with Hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Hypothermia's Effect on Hepatitis B Vaccination
A completed clinical trial evaluating the impact of neonatal hypothermia on the immune response to the Hepatitis B vaccine.