Hepatitis B
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CLINICAL_TRIALS trial_result · 2010-12-15Clinical Trial Update: PegIntron Versus Adefovir in the Treatment of Chronic Hepatitis B (CHB) e Antigen Positive Patients in Taiwan (P04498/MK-4031-278) [Phase 3]
Phase 3 clinical trial comparing PegIntron (pegylated interferon alfa-2b) versus Adefovir in HBeAg-positive chronic hepatitis B patients in …
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CLINICAL_TRIALS trial_result · 2010-12-14Clinical Trial Update: Hepatitis B Vaccination Through Syringe Exchange Programs: A Randomized, Controlled Trial of Vaccination Schedules [Phase 4]
A Phase 4 randomized trial compares different hepatitis B vaccination schedules delivered through syringe exchange programs. The study has c…
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: The Efficacy and Safety of Entecavir Treatment of Patients With Acute on Chronic Hepatitis B Liver Failure [Phase 2]
Phase 2 trial assessing the efficacy and safety of entecavir in patients with acute-on-chronic hepatitis B–related liver failure.
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CLINICAL_TRIALS trial_result · 2010-12-07Clinical Trial Update: Therapeutic Effects of Liver Failure Patients Caused by Chronic Hepatitis B After Autologous MSCs Transplantation
This update reports on the completed trial evaluating autologous mesenchymal stem cell transplantation for liver failure due to chronic hepa…
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CLINICAL_TRIALS trial_result · 2010-11-24Clinical Trial Update: Study of Adefovir Dipivoxil for Korean Patients With Chronic Hepatitis B(CHB) Who Have Completed ADF 103814 [Phase 4]
Phase 4 study of adefovir dipivoxil in Korean patients with chronic hepatitis B who completed prior study ADF 103814; results were posted.
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CLINICAL_TRIALS trial_result · 2010-11-18Clinical Trial Update: A Study in Korea of Entecavir Versus Lamivudine in Adults With Chronic Hepatitis B Infection [Phase 4]
Phase 4 study in Korea comparing entecavir with lamivudine in adults with chronic hepatitis B; results were posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-11-02Clinical Trial Update: Optimizing Hepatitis B Vaccine Response Through the Use of a Topical Immune Modulator [Phase 1, Phase 2]
Clinical trial update reporting Phase 1/2 results for a topical immune modulator intended to enhance the Hepatitis B vaccine response. The s…
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CLINICAL_TRIALS trial_result · 2010-10-15Clinical Trial Update: Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosis [Phase 4]
Phase 4 clinical trial update for adefovir dipivoxil in patients with chronic hepatitis B and advanced fibrosis or cirrhosis; trial complete…
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CLINICAL_TRIALS trial_result · 2010-09-17Clinical Trial Update: The Safety and Immunogenicity of Recombinant Hepatitis B Vaccines in the Health Neonates [Phase 3]
Phase 3 trial assessing safety and immunogenicity of a recombinant hepatitis B vaccine in healthy neonates; study completed.
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CLINICAL_TRIALS trial_result · 2010-08-26Clinical Trial Update: Long-Term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,6 Month Schedule [Phase 3]
Phase 3 trial update on long-term immune persistence of GSK combined Hepatitis A & B vaccine administered on a 0,6 month schedule; results c…
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CLINICAL_TRIALS trial_result · 2010-08-26Clinical Trial Update: Long-Term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,1,6 Month Schedule [Phase 3]
Phase 3 trial assessing long-term immune persistence of GSK's combined Hepatitis A & B vaccine given at 0, 1, 6 months; study completed with…
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CLINICAL_TRIALS trial_result · 2010-08-10Clinical Trial Update: A Phase IIIb Study to Compare Entecavir Plus Tenofovir vs. Adefovir Added to Continuing Lamivudine Therapy in Adult Patients With Lamivudine-Resistant Hepatitis B Infection [Phase 3]
Phase IIIb trial comparing entecavir plus tenofovir to adding adefovir to continuing lamivudine in lamivudine-resistant chronic hepatitis B;…
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CLINICAL_TRIALS trial_result · 2010-07-15Clinical Trial Update: LT F-up Study 16-20 Yrs After Vaccine Dose of Hepatitis B With/Without HBIg in Newborns to HBeAg+ Mothers [Phase 4]
Long-term follow-up results (16-20 years) from a Hepatitis B vaccination study in newborns of HBeAg-positive mothers, comparing with and wit…
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CLINICAL_TRIALS trial_result · 2010-07-05Clinical Trial Update: Evaluation of Antibody Persistence & Immune Memory in Subjects Vaccinated During Adolescence With Twinrix™ [Phase 4]
Phase 4 trial updating antibody persistence and immune memory after adolescence vaccination with Twinrix, focusing on Hepatitis A and B.
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CLINICAL_TRIALS trial_result · 2010-07-02Clinical Trial Update: Comparison of Entecavir to Adefovir in Chronic Hepatitis B Virus (HBV) Patients With Hepatic Decompensation [Phase 3]
Phase 3 trial comparing entecavir versus adefovir in adults with chronic hepatitis B and hepatic decompensation; study completed with result…
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CLINICAL_TRIALS trial_result · 2010-06-29Clinical Trial Update: Pegasys Plus Entecavir Versus Entecavir Alone for Hepatitis Be Antigen-Positive Chronic Hepatitis B [Phase 4]
Phase 4 clinical trial comparing Pegasys (pegylated interferon alfa-2a) plus entecavir versus entecavir alone for Hepatitis Be antigen-posit…
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CLINICAL_TRIALS trial_result · 2010-06-22Clinical Trial Update: 48 Weeks Combination Therapy for Patients With HBeAg-negative Chronic Hepatitis B Virus (HBV) Infection [Phase 3]
Phase 3 trial update reporting on 48 weeks of combination therapy for patients with HBeAg-negative chronic hepatitis B infection; the study …
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CLINICAL_TRIALS trial_result · 2010-06-22Clinical Trial Update: Influence of Hepatic Steatosis on the Therapeutic Effect of Entecavir in Chronic Hepatitis B Patients [Phase 4]
A Phase 4 clinical trial from Zhejiang University is investigating how hepatic steatosis influences the therapeutic effect of entecavir in c…
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CLINICAL_TRIALS trial_result · 2010-06-11Clinical Trial Update: Treatment With Peginterferon Alfa-2a (40 KD) of Chronic Hepatitis B Patients, Who Have Failed Anti-viral Treatment [Phase 4]
Phase 4 clinical trial evaluating peginterferon alfa-2a for chronic hepatitis B patients who failed antiviral therapy; the study status is c…
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CLINICAL_TRIALS trial_result · 2010-06-07Clinical Trial Update: HBV-specific T-cell Immunity in Individuals With HIV/HBV Co-infection
The update reports on HBV-specific T-cell immunity in individuals with HIV/HBV co-infection. The trial (NCT00476723) has completed.
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CLINICAL_TRIALS trial_result · 2010-06-02Clinical Trial Update: Hepatitis B Vaccination in HIV-infected Persons [Phase 4]
A Phase 4 clinical trial assessing Hepatitis B vaccination in HIV-infected persons has completed, reporting safety and immune response outco…
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CLINICAL_TRIALS trial_result · 2010-05-19Clinical Trial Update: A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Negative Chronic Hepatitis B [Phase 3]
A Phase 3 trial comparing tenofovir disoproxil fumarate (Viread) with adefovir dipivoxil in HBeAg-negative chronic hepatitis B has completed…
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CLINICAL_TRIALS trial_result · 2010-05-19Clinical Trial Update: A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Positive Chronic Hepatitis B [Phase 3]
Phase 3 trial comparing tenofovir disoproxil fumarate to adefovir dipivoxil in HBeAg-positive chronic hepatitis B was completed, with result…
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CLINICAL_TRIALS trial_result · 2010-03-15Clinical Trial Update: The Effect of Viral Load on Intrahepatic Recurrence in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC) [NA]
A completed clinical trial investigating how viral load influences intrahepatic recurrence in HBV-related hepatocellular carcinoma, with res…
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CLINICAL_TRIALS trial_result · 2010-02-24Clinical Trial Update: Randomized Controlled Trial of Tenofovir in Patients of Reactivation of Hepatitis B Presenting as Acute on Chronic Liver Failure [Phase 4]
A Phase 4 randomized trial evaluated Tenofovir for hepatitis B reactivation presenting as acute-on-chronic liver failure, and the study has …