Hepatitis B
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CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: Immunogenicity and Safety of the Hepatitis B Vaccine Hepavax-Gene TF and a Comparator Hepatitis B Vaccine in Newborns [Phase 3]
Phase 3 trial update reporting immunogenicity and safety data for the Hepavax-Gene TF hepatitis B vaccine in newborns, compared with a compa…
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CLINICAL_TRIALS trial_result · 2014-03-04Clinical Trial Update: Rollover Protocol Continued Access to Tenofovir Disoproxil Fumarate (TDF) for Subjects in Taiwan [Phase 2]
This update confirms that the rollover/continued-access protocol for Tenofovir Disoproxil Fumarate in hepatitis B patients in Taiwan has com…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Serum Hepatitis B Surface Antigen Levels to Guide the Stopping of Entecavir in HBeAg-negative Chronic Hepatitis B
A completed clinical trial evaluating whether Hepatitis B surface antigen levels can guide stopping entecavir in patients with HBeAg-negativ…
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CLINICAL_TRIALS trial_result · 2014-02-17Clinical Trial Update: Modified Process Hepatitis B Vaccine in Japanese Young Adults (V232-062) [Phase 3]
A Phase 3 clinical trial update reports results for a modified process Hepatitis B vaccine in Japanese young adults; results were posted in …
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CLINICAL_TRIALS trial_result · 2014-02-17Clinical Trial Update: Adefovir and Lamivudine for Entecavir Resistance (ALTER Study) [Phase 4]
Phase 4 ALTER study evaluating the use of adefovir and lamivudine for patients with entecavir-resistant chronic hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2014-02-13Clinical Trial Update: Efficacy and Safety Study of Entecavir Plus Tenofovir in Patients With Chronic Hepatitis B Who Failed Previous Treatment [Phase 3]
Phase 3 trial evaluating the efficacy and safety of combining entecavir with tenofovir in patients with chronic hepatitis B who failed prior…
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CLINICAL_TRIALS trial_result · 2014-02-04Clinical Trial Update: Immunogenicity of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared With PENTAXIM™ and ENGERIX B® at 2-3-4 Months Schedule [Phase 3]
Phase 3 trial assessing the immunogenicity of a combined DTaP-IPV-Hep B-PRP~T vaccine versus PENTAXIM and ENGERIX B in infants at 2- to 4-mo…
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CLINICAL_TRIALS trial_result · 2014-01-31Clinical Trial Update: Antiviral Efficacy of Switching to ETV Plus TDF [Phase 4]
Phase 4 clinical trial evaluating antiviral efficacy when switching chronic hepatitis B patients to a combination of entecavir and tenofovir…
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CLINICAL_TRIALS trial_result · 2014-01-24Clinical Trial Update: Hepatitis B Antigen Kidney Graft Into Protective Level Hepatitis B Antibody Recipients
The update describes a clinical trial evaluating kidney transplants from hepatitis B surface antigen-positive donors into recipients with pr…
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CLINICAL_TRIALS trial_result · 2014-01-14Clinical Trial Update: Study of PR5I, a Pediatric Combination Vaccine With Enhanced Hepatitis B Component Given Concomitantly With Prevnar® [Phase 2]
Phase 2 study evaluating PR5I, a pediatric combination vaccine with an enhanced Hepatitis B component, given concomitantly with Prevnar; the…
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CLINICAL_TRIALS trial_result · 2014-01-13Clinical Trial Update: Entecavir Plus Adefovir in Lamivudine-Resistant Chronic Hepatitis B Patients Who Fail Lamivudine Plus Adefovir [Phase 4]
This Phase 4 trial assesses the combination of entecavir and adefovir in lamivudine-resistant chronic hepatitis B patients who fail lamivudi…
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CLINICAL_TRIALS trial_result · 2014-01-08Clinical Trial Update: Incidence of Hepatitis B Virus (HBV) Reactivation in HBsAg Negative/HBcAb Positive Lymphoma Patients Treated With RCHOP [Phase 2, Phase 3]
This clinical trial update discusses the incidence of hepatitis B reactivation in lymphoma patients who are HBsAg negative and HBcAb positiv…
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CLINICAL_TRIALS trial_result · 2014-01-07Clinical Trial Update: Observational Study of the Durability of Seroconversion Chronic HBV Patients Who Seroconverted in a Previous Gilead-Sponsored Study of ADV.
This clinical trial update reports on the durability of seroconversion in chronic hepatitis B patients who previously seroconverted in a Gil…
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CLINICAL_TRIALS trial_result · 2014-01-03Clinical Trial Update: Safety and Pharmacokinetics Study of Healthy Male Adults When Repeatedly Administered Through Intravenous Injection [Phase 1]
This is a Phase 1 safety and pharmacokinetics study in healthy male adults receiving repeated intravenous injections, sponsored by Green Cro…
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CLINICAL_TRIALS trial_result · 2014-01-01Clinical Trial Update: Hepatitis B Virus HBeAg-negative Genotype D Patients and Hepatocellular Carcinoma
A clinical trial investigating Hepatitis B patients (HBeAg-negative, genotype D) with hepatocellular carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2013-12-30Clinical Trial Update: Study of the Immunogenicity and Efficacy of HBsAg Vaccine in Combination With Standard Antiviral Therapy With HB110E [NA]
This clinical trial update reports the completed study of an HBsAg vaccine in combination with standard antiviral therapy HB110E for chronic…
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CLINICAL_TRIALS trial_result · 2013-12-20Clinical Trial Update: A Study Evaluating GS-9620 in Virologically Suppressed Subjects With Chronic Hepatitis B Virus Infection [Phase 1]
This Phase 1 trial update reports completion of a study evaluating GS-9620 (vesatolimod) in adults with virologically suppressed chronic hep…
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CLINICAL_TRIALS trial_result · 2013-12-10Clinical Trial Update: Comparison of DTaP-HB-PRP~T Combined Vaccine to Tritanrix-HepB/Hib™, Both Given Concomitantly With Oral Polio Vaccine [Phase 3]
A Phase 3 trial comparing the DTaP-HB-PRP-T combined vaccine to Tritanrix-HepB/Hib, both given concomitantly with oral polio vaccine; result…
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CLINICAL_TRIALS trial_result · 2013-12-06Clinical Trial Update: Prevention of Hepatitis B Virus Mother-to-child Transmission by Serovaccination.
An update on a completed clinical trial investigating serovaccination to prevent mother-to-child transmission of hepatitis B.
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CLINICAL_TRIALS trial_result · 2013-11-26Clinical Trial Update: Hepatitis B Vaccine Clinical Trial [Phase 3]
Phase 3 clinical trial of a Hepatitis B vaccine has completed. The update provides no results.
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CLINICAL_TRIALS trial_result · 2013-11-26Clinical Trial Update: Interruption of Maternal-to-Infant Transmission of Hepatitis B by Means of Hepatitis B Immune Globulin [Phase 3]
A Phase 3 clinical trial evaluating Hepatitis B immune globulin to interrupt maternal-to-infant transmission of Hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2013-11-21Clinical Trial Update: Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB-PRP~T Combined Vaccine or Tritanrix-HepB/Hib™ [Phase 3]
Phase 3 immunogenicity study assessing antibody persistence and booster effects of the DTaP-HB-PRP~T combined vaccine (Tritanrix-HepB/Hib) d…
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CLINICAL_TRIALS trial_result · 2013-11-14Clinical Trial Update: Immunogenicity Study of Antibody Persistence and Booster Effect of DTaP-HB PRP~T Combined Vaccine in Filipino Infants [Phase 3]
Phase 3 immunogenicity update evaluating antibody persistence and booster response of the DTaP-HB PRP-T combination vaccine in Filipino infa…
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CLINICAL_TRIALS trial_result · 2013-11-14Clinical Trial Update: A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis B [Phase 1]
A Phase 1 trial of GS-9620 (vesatolimod) in treatment-naive subjects with chronic hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2013-11-04Clinical Trial Update: Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B With Poor Response to Other Drugs [Phase 3]
Phase 3 study of GSK548470 in patients with compensated chronic hepatitis B who had poor response to other drugs has completed, and results …