Hepatitis B
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: HBsAg Loss Adding Pegylated Interferon in HBeAg-negative Patients [NA]
This completed clinical trial investigates whether adding pegylated interferon alfa-2a can promote HBsAg loss in patients with chronic hepat…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of ALG-000184 after single and multiple doses in health…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Open-Label Study of AB-729, Nucleos(t)Ide Analogue and Pegylated Interferon Alfa-2a in Subjects With Chronic Hepatitis B Infection [Phase 2]
Open-label Phase 2 study of AB-729 with pegylated interferon alfa-2a for chronic hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk
Exact Sciences is reporting on the performance of a multi-target hepatocellular carcinoma test in individuals at increased risk. The clinica…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: Safety and Immunogenicity of a Naked DNA-based Vaccine Therapy in Patients With Chronic Hepatitis B [Phase 1]
This Phase 1 clinical trial evaluated the safety and immunogenicity of a naked DNA-based vaccine therapy in adults with chronic hepatitis B.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in Zimbabwe [NA]
This clinical trial update reports the completion of a study evaluating point-of-care diagnostics for sexually transmitted infections and an…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of DTwP-HepB-Hib-IPV (SHAN6™) Vaccine Administered Concomitantly With Routine Pediatric Vaccines to Healthy Infants and Toddlers in Thailand [Phase 3]
Phase 3 study evaluating the DTwP-HepB-Hib-IPV (SHAN6) vaccine administered with routine vaccines in healthy infants and toddlers in Thailan…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B [Phase 2]
Phase 2 trial evaluating multiple combination therapies for chronic hepatitis B; the study has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: A Clinical Study of HT-101 and/or HT-102 in Patients With Chronic Hepatitis B Virus Infection [Phase 1, Phase 2]
This clinical trial update notes that HT-101 and HT-102 are being studied in Phase 1/Phase 2 for chronic hepatitis B, and the trial status i…
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Efficacy of VTP-300 in Chronic Hepatitis B Infection [Phase 2]
Phase 2 trial evaluating the efficacy of VTP-300 in chronic hepatitis B infection; the document notes an active, not recruiting status.
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Metabolic Associated Fatty Liver Disease and Pancreatic Steatosis in Obese Versus Lean Chronic Hepatitis B Patients
A clinical trial comparing metabolic associated fatty liver disease and pancreatic steatosis in obese versus lean patients with chronic hepa…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D)
The IMPHROVE-D trial reports improvement of portal hypertension in patients with hepatitis D during viral suppression; the study is active b…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: HBV Virions Bound Proteins [NA]
A clinical trial investigating HBV virion-bound proteins for Hepatitis B virus infection has completed.
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Using Flavonoids to Kill Hepatitis B Virus [Phase 4]
A Phase 4 clinical trial evaluating flavonoids as a potential treatment for Hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Treatment of Patients With Chronic Hepatitis B With Hepatitis B Immunoglobulins [Phase 2]
A Phase 2 trial evaluating Hepatitis B immunoglobulin for chronic hepatitis B was terminated.
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Hepatitis B Virus Reactivation in COVID-19
The clinical trial update notes the completion of a study investigating hepatitis B virus reactivation in patients with COVID-19 pneumonia a…
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: First in Human Study of ChAdOx1-HBV in Healthy Participants and Participants With Chronic hepB Infection [Phase 1]
First-in-human Phase 1 study of the ChAdOx1-HBV vaccine in healthy individuals and patients with chronic hepatitis B; results have been post…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate [Phase 1, Phase 2]
This clinical trial update describes TherVacB, a heterologous protein prime/MVA boost therapeutic vaccine candidate for chronic hepatitis B,…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB) [Phase 2]
Phase 2 study evaluating the safety and efficacy of Selgantolimod-containing combination therapies for chronic hepatitis B has completed wit…
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CLINICAL_TRIALS trial_result · 2025-07-23Clinical Trial Update: A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334 in Subjects With Chronic Hepatitis B Virus Infection [Phase 1]
Phase 1 trial evaluating the safety, pharmacokinetics, and antiviral activity of ABI-4334 in adults with chronic hepatitis B has completed.
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: B-Enhancement of HBV Vaccination in Persons Living With HIV (BEe-HIVe): Evaluation of HEPLISAV-B [Phase 3]
A Phase 3 trial (BEe-HIVe) evaluated HEPLISAV-B for hepatitis B vaccination in persons living with HIV. The study has completed and results …
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: A Study to Evaluate the Relative Bioavailability of Subcutaneous Bepirovirsen When Delivered From a Vial or Prefilled Syringe Fitted With a Safety Syringe Device in Healthy Adult Participants [Phase 1]
A Phase 1 study assessed the relative bioavailability of subcutaneous bepirovirsen when administered from a vial versus a prefilled syringe …
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Prophylactic Entecavir for HBV Reactivation in Past HBV Infected Patients With Hematopoietic Stem Cell Transplantation [NA]
Enrollment by invitation is ongoing for prophylactic entecavir to prevent hepatitis B reactivation in patients with past HBV infection under…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Clinical Efficacy of Pegylated Interferon Alpha-2b Combined With Nucleos(t)Ide Analogues in the Treatment of Chronic Hepatitis B Patients [Phase 4]
Phase 4 clinical trial update evaluating pegylated interferon alfa-2b in combination with nucleos(t)ide analogues for chronic hepatitis B, w…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: Peg-interferon for Inactive Chronic Hepatitis B Carriers [Phase 2, Phase 3]
Clinical trial update reports completion of Phase 2/3 studies of pegylated interferon for inactive hepatitis B carriers.