Hepatitis B

CLINICAL_TRIALS trial_result · 2017-01-24

Clinical Trial Update: Clinical Efficacy of ABX203 Therapeutic Vaccine in HBeAg Negative Patients With Chronic Hepatitis B [Phase 2, Phase 3]

This clinical trial update reports the completion of a Phase 2/3 study evaluating the clinical efficacy of ABX203 Therapeutic Vaccine in HBe…

CLINICAL_TRIALS trial_result · 2017-01-23

Clinical Trial Update: Study of Hepalatide(L47) at Phase Ib in Healthy Volunteers [Phase 1]

Phase Ib study of Hepalatide (L47) in healthy volunteers has completed. The update notes the completion of the trial investigating safety an…

CLINICAL_TRIALS trial_result · 2017-01-18

Clinical Trial Update: Second Stage:Open-label Study of Therapeutic Hepatitis B Vaccine (Mimogen-based) for Chronic Hepatitis B [Phase 2]

Phase 2 open-label study assessing a Mimogen-based therapeutic vaccine for chronic hepatitis B has completed with posted results.

CLINICAL_TRIALS trial_result · 2017-01-18

Clinical Trial Update: Phase 2 Trial of Therapeutic Hepatitis B Vaccine (Mimogen-based) for Chronic Hepatitis B [Phase 2]

Phase 2 trial of a Mimogen-based therapeutic hepatitis B vaccine for chronic hepatitis B has completed with results posted.

CLINICAL_TRIALS trial_result · 2017-01-12

Clinical Trial Update: A Study of the Safety and Efficacy of Pegylated Inferferon Alfa-2b (PEG-Intron™) Versus Pegylated Interferon Alfa-2a (PEGASYS™) in Participants With Chronic Hepatitis B (P08450) [Phase 3]

Phase 3 trial comparing PEG-Intron to PEGASYS in chronic hepatitis B was terminated with posted results in 2017.

CLINICAL_TRIALS trial_result · 2017-01-11

Clinical Trial Update: An Hepatitis B Vaccine Model for HIV Vaccine Trials in Drug Users [Phase 3]

Phase 3 clinical trial update evaluating a Hepatitis B vaccine model used for HIV vaccine trials in drug users; the study status is complete…

CLINICAL_TRIALS trial_result · 2017-01-10

Clinical Trial Update: Prophylactic Use of Entecavir for HBsAg Negative/HBcAb Positive/Hepatitis B Virus DNA Negative Patients With Lymphoma [Phase 4]

Phase 4 trial investigating prophylactic Baraclude (Entecavir) to prevent hepatitis B reactivation in patients who are HBsAg negative/HBcAb …

CLINICAL_TRIALS trial_result · 2016-12-29

Clinical Trial Update: Performance of the HBV ELISPOT in the Detection of the T Cellular Immune Response in Patients Infected by HBV or Cured

Clinical trial update evaluating how the HBV ELISPOT assay performs in detecting T-cell immune responses in patients with hepatitis B infect…

CLINICAL_TRIALS trial_result · 2016-12-29

Clinical Trial Update: Study to Evaluate Antibody Persistence in Children Previously Vaccinated With Infanrix Hexa™ or Infanrix-IPV/Hib™ [Phase 4]

Phase 4 study assessing antibody persistence in children previously vaccinated with Infanrix Hexa or Infanrix-IPV/Hib; completed with result…

CLINICAL_TRIALS trial_result · 2016-12-14

Clinical Trial Update: Active Drug Comparative Trial to Evaluate the Antiviral Activity and Safety in Chronic Hepatitis B Patients [Phase 4]

A Phase 4 comparative clinical trial evaluating antiviral activity and safety of an active drug in adults with chronic hepatitis B.

CLINICAL_TRIALS trial_result · 2016-12-13

Clinical Trial Update: Application of HBV Rapid Tests as a Tool for Wide-Use Screening [NA]

Completed a clinical trial assessing HBV rapid tests as a wide-use screening tool for Hepatitis B and related liver diseases. The study resu…

CLINICAL_TRIALS trial_result · 2016-12-13

Clinical Trial Update: Pilot Study Evaluating the Use of Simultaneous HBV, HCV, and HIV Rapid Tests [NA]

A pilot study evaluated the use of simultaneous rapid tests for HIV, hepatitis B, and hepatitis C; the trial is completed and results were p…

CLINICAL_TRIALS trial_result · 2016-11-30

Clinical Trial Update: Immunogenicity and Safety of GSK Biologicals' Infanrix Hexa in Infants [Phase 4]

Phase 4 trial update on immunogenicity and safety of Infanrix Hexa in infants, with results posted after completion.

CLINICAL_TRIALS trial_result · 2016-11-28

Clinical Trial Update: Increasing Hepatitis B Screening Among Korean Church Attendees [Phase 3]

A Phase 3 clinical trial aimed at increasing Hepatitis B screening among Korean church attendees has completed.

CLINICAL_TRIALS trial_result · 2016-11-22

Clinical Trial Update: The Safety and Dose-range Study of Metacavir Enteric-coated Capsules in Patients With Chronic Hepatitis B [Phase 2]

This document provides a status update on a Phase 2 safety and dose-range study of Metacavir Enteric-coated Capsules in patients with Chroni…

CLINICAL_TRIALS trial_result · 2016-11-11

Clinical Trial Update: Effect of Cyanobacteria Patients With Chronic Hepatitis B Surface Antigen Quantitative Concentration [NA]

This clinical trial evaluates whether cyanobacteria affect the quantitative concentration of hepatitis B surface antigen (HBsAg) in adults w…

CLINICAL_TRIALS trial_result · 2016-11-09

Clinical Trial Update: Tenofovir Disoproxil Fumarate vs. Entecavir in Chronic Hepatitis B Patients With Partial Virologic Response to Entecavir [Phase 4]

A Phase 4 trial comparing tenofovir disoproxil fumarate with entecavir in chronic hepatitis B patients who had a partial virologic response …

CLINICAL_TRIALS trial_result · 2016-11-07

Clinical Trial Update: Effect of RO6871765 and RO7011785 on Immune Response With the Stimulation of Peripheral Blood Mononuclear Cells (PBMCs) in Chinese Healthy Volunteers and Chronic Hepatitis B Patients

This clinical trial update describes the immune response effects of Roche investigational compounds RO6871765 and RO7011785 on stimulation o…

CLINICAL_TRIALS trial_result · 2016-11-04

Clinical Trial Update: Immunogenicity and Safety of a DTPa-HBV-IPV/Hib Vaccine Given at 2, 3 and 4 Months of Age [Phase 2]

Phase 2 trial update evaluating the immunogenicity and safety of a pentavalent DTPa-HBV-IPV/Hib vaccine given at 2, 3, and 4 months of age.

CLINICAL_TRIALS trial_result · 2016-11-03

Clinical Trial Update: A Study of Pegylated Interferon Alfa-2a and Lamivudine in Patients With HBeAg-Negative Chronic Hepatitis B Virus (HBV) [Phase 3]

Phase 3 study evaluating a combination of pegylated interferon alfa-2a and lamivudine in patients with HBeAg-negative chronic hepatitis B; r…