Hepatitis B
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Liver Fibrosis in Zambian HIV-HBV Co-infected Patients
This ClinicalTrials.gov update concerns a study in Zambian patients co-infected with HIV and hepatitis B, investigating liver fibrosis and r…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Immunogenicity and Safety Following In-House Recombinant Hepatitis B Vaccine in Indonesian Population (Phase III) [Phase 3]
Phase III clinical trial evaluating immunogenicity and safety of PT Bio Farma's in-house recombinant hepatitis B vaccine in Indonesia; curre…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Real-world Study on Liver Cancer Risk in Chronic Hepatitis B Patients With Family History of Liver Cancer
A real-world study to evaluate liver cancer risk in patients with chronic hepatitis B who have a family history of liver cancer, sponsored b…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: Hydronidone Capsules in Long-term Treatment in Patients With Chronic Viral Hepatitis B Liver Fibrosis [Phase 3]
Phase 3 clinical trial update for Hydronidone Capsules in chronic hepatitis B with liver fibrosis; recruitment is ongoing.
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Antiviral Prophylaxis and Infant Vaccination to Prevent Perinatal Hepatitis B Infection [Phase 3]
Phase 3 clinical trial evaluating antiviral prophylaxis during pregnancy and infant vaccination to prevent perinatal Hepatitis B infection; …
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: Vaccinal Effect of HBsAg Monoclonal Ab VIR-3434 in Chronic Hepatitis B Infection [VISION] [Phase 2]
A Phase 2 clinical trial (VISION) is evaluating VIR-3434, an HBsAg monoclonal antibody, for chronic hepatitis B infection and is currently r…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Effect of Long-Term Use of Tenofovir (TDF) on Bone Density in Patients With Chronic Hepatitis B
This trial update describes a study examining the effect of long-term Tenofovir Disoproxil Fumarate on bone density in patients with chronic…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Combination Therapy of BRII-179, BRII-835 and PEG-IFNα in Participants With Chronic Hepatitis B Virus (HBV) Infection (ENHANCE) [Phase 2]
A Phase 2 trial (ENHANCE) is evaluating a triple regimen of BRII-179, BRII-835, and PEG-IFNα for chronic hepatitis B infection, currently re…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: The HOPE Study: Characterizing Patients With Hepatitis B and C
The HOPE Study is currently recruiting to characterize patients with chronic hepatitis B and chronic hepatitis C.
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Comparison of TAF and TDF in Preventing Mother-to-Child Transmission of HBV in Pregnancies With High Viral Loads [NA]
This clinical trial compares tenofovir alafenamide (TAF) versus tenofovir disoproxil fumarate (TDF) for preventing mother-to-child transmiss…
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CLINICAL_TRIALS research · 2025-05-01Clinical Trial Update: Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patients [Phase 4]
Phase 4 clinical trial update: a peginterferon treatment study for inactive chronic hepatitis B is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: A Real-World Study of Antiviral Therapy in Children With Chronic Hepatitis B
A real-world study evaluating antiviral therapy for chronic hepatitis B in children is planned and currently not recruiting.
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate [Phase 1]
A Phase 1 clinical trial is evaluating a heterologous protein prime with an MVA boost therapeutic vaccine candidate for chronic Hepatitis B,…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Discontinuation of Antiviral Therapy as a Strategy to Cure Hepatitis B [NA]
The update discusses a study exploring whether discontinuing antiviral therapy can lead to cure in chronic hepatitis B.
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Hepatitis Delta Virus Infection: Cross-sectional Study in Patients With Chronic Hepatitis B Virus Infection
An observational cross-sectional study evaluating Hepatitis D infection in patients with chronic Hepatitis B infection; the study is current…
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CLINICAL_TRIALS research · 2025-04-13Clinical Trial Update: The Clinical Cure Project of Chronic Hepatitis B in China [Phase 4]
Phase 4 clinical trial in China titled 'The Clinical Cure Project of Chronic Hepatitis B' is currently active but not recruiting, sponsored …
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Sequential PEG-IFN for HBV After Ending RNA-targeted Regimens [NA]
A clinical trial is evaluating sequential pegylated interferon therapy for chronic hepatitis B after completion of RNA-targeted regimens; th…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure) [Phase 2]
Phase 2 long-term follow-up trial to evaluate durability of response to Bepirovirsen in previous Hepatitis B study participants; recruitment…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Effect of Tenofovir (TDF) on Renal Function in Patients With Chronic Hepatitis B
This clinical trial update outlines a study to assess the impact of Tenofovir disoproxil fumarate (TDF) on renal function in patients with c…
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CLINICAL_TRIALS research · 2025-04-03Clinical Trial Update: A Study of LP-128 Capsules in Healthy Subjects [Phase 1]
Phase 1 study evaluating LP-128 capsules in healthy subjects is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Antiretroviral Pregnancy Registry (APR): Multi-sponsor Registry to Detect Any Major Teratogenic Effect Involving Any of the Registry Drugs When Administered to Pregnant People.
This clinical trial update describes the Antiretroviral Pregnancy Registry (APR), a multi-sponsor effort to monitor for major teratogenic ef…
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Pegylated Interferon Alfa-2b in Reducing Relapse Rates After Nucleos(t)ide Analogue Withdrawal in HBeAg-negative CHB Patients with Low Level HBsAg [Phase 4]
A Phase 4 study evaluating whether pegylated interferon alfa-2b can reduce relapse after stopping nucleos(t)ide analogue therapy in HBeAg-ne…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: Accupower ® HBV Performance Evaluation Quant Kit Bioneer Existation FA 96/384
CerbaXpert is conducting a clinical trial evaluating the Accupower HBV Performance Evaluation Quant Kit Bioneer Existation FA 96/384 for Hep…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK) [Phase 4]
A Phase 4 clinical trial is examining whether stopping long-term nucleos(t)ide analogue therapy is non-inferior to continuing therapy in adu…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease
This is an ongoing clinical trial follow-up study investigating Chronic hepatitis B patients with comorbid Nonalcoholic fatty liver disease,…