Hepatitis B
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Prospective Cohort Study on PEG-IFN-α-2b in Improving Clinical Cure Rate of Pediatric Patients With Chronic Hepatitis B [Phase 4]
A Phase 4 prospective cohort trial is evaluating PEG-IFN-α-2b to improve clinical cure rates in pediatric patients with chronic hepatitis B;…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B [Phase 1]
A Phase 1 clinical trial evaluating a Toll-like receptor 9 adjuvanted vaccine for chronic hepatitis B. The study is currently recruiting and…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: A Study to Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney Disease [Phase 1]
Phase 1 study evaluating blood levels of Bepirovirsen in adults with severe or moderate kidney disease. The sponsor is GlaxoSmithKline and t…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Reducing Vertical Transmission of Hepatitis B in Africa [Phase 3]
A Phase 3 clinical trial to reduce vertical transmission of Hepatitis B in Africa is underway. It is sponsored by the University of Alabama …
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Safely Discontinue Antiviral Treatment in Patients With Chronic Hepatitis B [Phase 4]
A Phase 4 clinical trial is evaluating whether safely discontinuing antiviral therapy is possible in adults with chronic hepatitis B, and th…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Study of LW231 in Participants With Chronic Hepatitis B [Phase 1, Phase 2]
Ongoing Phase 1/2 clinical trial of LW231 for chronic hepatitis B, with recruiting status and sponsor Shanghai Longwood Biopharmaceuticals C…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: A Phase II/III of Hepenofovir Fumarate Tablets (HTS) for Chronic Hepatitis B [Phase 2, Phase 3]
A Phase II/III study of Hepenofovir Fumarate Tablets (HTS) for chronic hepatitis B is ongoing, with status shown as active but not currently…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Study to Evaluate Immunogenicity and Safety of TVAX-008 Injection in Non/Treated Chronic Hepatitis B Patients With HBsAg≤20IU/ml or HBsAg Negative Without Serological Conversion [EARLY_Phase 1]
Early-phase 1 trial update evaluating the immunogenicity and safety of TVAX-008 injections in chronic hepatitis B patients with low or negat…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Immune Dynamics in the Natural History of Chronic HBV Infection
A recruiting clinical trial is investigating immune dynamics in the natural history of chronic hepatitis B virus infection, sponsored by Nan…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B [Phase 1]
This document reports a Phase 1 study to evaluate safety and antiviral activity of PBGENE-HBV in adults with chronic hepatitis B. The trial …
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of AHB-137 in Healthy Participants and HBeAg-negative Chronic Hepatitis B (CHB) Patients [Phase 1, Phase 2]
A research update describing a Phase 1/2 clinical trial to evaluate the safety and efficacy of AHB-137 in healthy participants and patients …
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Study to Evaluate the Efficacy and Safety of AHB-137 in Treatment-naive Participants With Chronic Hepatitis B (CHB) [Phase 2]
A Phase 2 study evaluating AHB-137 in treatment-naive adults with chronic hepatitis B is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of TVAX-008 Injection in Treated Patients With Chronic Hepatitis B [Phase 2]
This update reports on a multicenter, randomized, double-blind, placebo-controlled Phase II study of TVAX-008 for chronic hepatitis B. The t…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus Infection [Phase 1, Phase 2]
A randomized, controlled Phase 1/Phase 2 trial evaluating a vaccine therapy for chronic hepatitis B infection. The study is currently not ye…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of TVAX-008 Injection in Chronic Hepatitis B Patients [Phase 2]
A multicenter Phase II randomized trial evaluating TVAX-008 injection for chronic Hepatitis B (HBV infection) is currently active but not re…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: An Observational Study of Patients With Chronic Hepatitis B (CHB) Infection
An observational study of patients with chronic hepatitis B infection has been terminated.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Gene Discovery in CHB Patients to Identify Unknown Pathways That Lead to B and NK Cell Deregulation [NA]
A recruiting clinical study in chronic hepatitis B patients aims to discover genes and pathways that cause deregulation of B cells and natur…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Observation Study on Reducing the Risk of Liver Cancer Associated With Hepatitis B (Zhiyuan) Project.
An observational study conducted by The First Affiliated Hospital of Zhengzhou University aims to reduce the risk of liver cancer in people …
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (A) [Phase 2]
Phase 2 clinical trial update describing a novel combination therapy strategy for chronic hepatitis B aiming for functional cure via sustain…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B [Phase 2]
A Phase 2 clinical trial update evaluating Imdusiran (AB-729) for chronic hepatitis B is recruiting, with assessments of intrahepatic and pe…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B) [Phase 2]
A Phase 2 clinical trial is evaluating a combination of an anti-PD-1 antibody and Peg-IFNα for chronic hepatitis B with the goal of sustaine…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Study of Tenofovir Alafenamide in HBV-Infected Pregnant Women [Phase 4]
A Phase 4 clinical trial is evaluating Tenofovir alafenamide in pregnant women with chronic hepatitis B and is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Risk Assessment for HBV-Related Liver Cancer
A recruiting clinical trial studying risk assessment for HBV-related liver cancer in patients with HBV-related liver cirrhosis.
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Investigate the Efficacy and Safety of BRII-835 (VIR-2218) and PEG-IFNα Combination Therapy in Chronic HBV Patients [Phase 2]
A Phase 2 clinical trial update describing ongoing evaluation of BRII-835 (VIR-2218) in combination with PEG-IFNα for chronic hepatitis B in…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Zinc Sulphate in Treatment Fibrosis in HBV Patient Receiving Antiviral Therapy [Phase 2]
A Phase 2 clinical trial evaluating zinc sulfate for treating liver fibrosis in patients with hepatitis B who are receiving antiviral therap…