Hepatitis B
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection [Phase 1]
This document reports a Phase 1 study to assess safety, tolerability, and pharmacokinetics of GIGA-2339 in participants with chronic hepatit…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Effect of Fufang Biejiaruangan Combined With Antiviral Therapy on the Incidence of Hepatocellular Carcinoma in Patients With Hepatitis B-related Cirrhosis: A Multicenter, Randomized, Placebo-controlled Study [NA]
A multicenter randomized controlled trial evaluating whether Fufang Biejiaruangan plus antiviral therapy reduces hepatocellular carcinoma in…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: The Treatment of PD-1 Antibody Combined With Peg-IFNα in NAs-suppressed CHB Patients [NA]
Clinical trial update on a PD-1 antibody combined with Peg-IFNα in hepatitis B patients whose nucleos(t)ide analog therapy is suppressed. Th…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Entecavir Resistance-Associated Mutations in Chronic HBV Patients in Turkey (STREAM Study)
A clinical study named STREAM is investigating entecavir resistance-related mutations in adults with chronic hepatitis B in Turkey; the tria…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Study on IB-001 Dose Response and Tolerability in Healthy Adults and Those With Chronic Hepatitis B [Phase 1]
An early-phase Phase 1 clinical trial evaluating dose response and tolerability of the investigational drug IB-001 in healthy adults and ind…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: MR Elastography for Assessing Liver Fibrosis in Chronic Hepatitis B
A clinical trial is recruiting to evaluate MR elastography as a noninvasive method to assess liver fibrosis in patients with chronic hepatit…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Umbilical Cord Mesenchymal Stem Cell for Liver Cirrhosis Patient Caused by Hepatitis B [Phase 1, Phase 2]
This entry reports a Phase 1/2 clinical trial using umbilical cord mesenchymal stem cells to treat liver cirrhosis caused by chronic hepatit…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Phase IIIc Clinical Study to Evaluate the Long-term Treatment of Hydronidone Capsules for Liver Fibrosis in Patients With Chronic Hepatitis B. [Phase 3]
Phase IIIc clinical trial to evaluate the long-term use of Hydronidone capsules for liver fibrosis in patients with chronic hepatitis B; sta…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Screening for Hepatitis B, Hepatitis C and AIDS Viruses Using Dried Blood Spot [NA]
Clinical trial update on screening for Hepatitis B, Hepatitis C, and AIDS viruses using dried blood spot; currently recruiting.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: "Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".
A French research trial aims to assemble a biological collection to develop preclinical translational models for tumors and chronic liver di…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Stopping Antiviral Treatment in Chronic Hepatitis B
This clinical trial update discusses stopping antiviral therapy in chronic hepatitis B. The study is sponsored by The University of Hong Kon…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME) [Phase 2]
Phase 2 trial update describing a study that compares ALG-000184 with tenofovir disoproxil fumarate in untreated adults with chronic hepatit…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus) [Phase 2]
Phase 2 study of bepirovirsen for hepatitis B in participants living with HIV and chronic hepatitis B infection; the trial is currently acti…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Prospective Clinical Performance Evaluation of the In-Vitro Diagnostics Medical Device MaGIA IBC for the CombIned screENing of HIV, Hepatitis B and Hepatitis C [NA]
Prospective clinical performance evaluation of the MaGIA IBC point-of-care device for combined screening of HIV, Hepatitis B, and Hepatitis …
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Clinical Performance Evaluation of MagIA IVD-MD Multiplex Testing (HIV/HBV/HCV/Syphilis)
Clinical performance evaluation of MagIA's multiplex HIV, HBV, HCV, and syphilis testing is ongoing, with the study currently recruiting.
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: HepB mAb19 in Individuals With Chronic Hepatitis B Infection [Phase 1]
This update indicates that a Phase 1 clinical trial of HepB mAb19 for chronic hepatitis B infection is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B Patients [Phase 4]
Phase 4 clinical trial update on empagliflozin for liver fibrosis and cirrhosis in chronic hepatitis B with NAFLD; currently active but not …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: A Phase 1/2, Open-Label, Single and Multiple Ascending Dose Study of CRMA-1001 in Adults With Chronic Hepatitis B [Phase 1, Phase 2]
This clinical trial update announces a Phase 1/2 open-label study of CRMA-1001 in adults with chronic hepatitis B, evaluating single and mul…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: To Evaluate the Efficacy, Safety and Population Pharmacokinetics of GST-HG141 in Patients With Chronic Hepatitis B (CHB) Who Have an Inadequate Response to Antiviral Drug Treatment [Phase 3]
Phase 3 trial to evaluate GST-HG141 in adults with chronic hepatitis B who have an inadequate response to antiviral therapy; study is curren…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: HBRN: Immune Regulation and Costimulation in Natural History and Therapeutic Outcome of Chronic Hepatitis B
A clinical trial update describing a University of Pennsylvania study on immune regulation and costimulation in the natural history and ther…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: HBRN: Immune Regulation and Costimulation in Natural History of Chronic Hepatitis B
University of Pennsylvania is conducting the HBRN study on immune regulation and costimulation in the natural history of chronic hepatitis B…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental Health. [Phase 4]
Phase 4 clinical trial update on managing hepatitis B and HPV-related cancers and associated mental health conditions. The study is currentl…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Rapid HIV, Hep C, and Syphilis Screening in a Rural Street Medicine Clinic
A clinical trial at West Virginia University aims to rapidly screen people for HIV, hepatitis C, syphilis, and hepatitis B in a rural street…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Entecavir With or Without Pegylated Interferon α-2b in Children Aged 3-6 Years With Immune-Active Chronic Hepatitis B [Phase 4]
A Phase 4 clinical trial evaluating entecavir with or without pegylated interferon alfa-2b in children aged 3-6 with immune-active chronic h…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Entecavir With or Without Pegylated Interferon α-2b in Children Aged 3-6 Years With Immune-Tolerant Chronic Hepatitis B [Phase 4]
A Phase 4 trial to evaluate entecavir with or without pegylated interferon alpha-2b in children aged 3-6 with immune-tolerant chronic hepati…