Hepatitis B
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CLINICAL_TRIALS research · 2017-06-20Clinical Trial Update: Is Hepatitis B Surface Antigen (HB s Ag) Enough Alone as a Screening Test Before Immunosuppressive Therapies? [NA]
A clinical trial update investigates whether Hepatitis B surface antigen alone is sufficient as a screening test before initiating immunosup…
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CLINICAL_TRIALS research · 2017-05-03Clinical Trial Update: The Investigation of Peginterferon Alfa-2a on Optimal in Chronic Hepatitis B Patients Who Have a High Risk of HCC [Phase 4]
A Phase 4 clinical trial is investigating peginterferon alfa-2a in chronic hepatitis B patients at high risk of hepatocellular carcinoma.
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CLINICAL_TRIALS research · 2017-04-21Clinical Trial Update: "Treatment of Active HBV With γδT Cells" Clinical Trial Protocol [EARLY_Phase 1]
This clinical trial protocol describes an early-phase (Phase 1) study to treat active hepatitis B using adoptive γδ T cell therapy.
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CLINICAL_TRIALS research · 2017-03-31Clinical Trial Update: "Real-life" Cohort Study on Patients With Chronic HBV Infection in Jiangsu
A real-world, observational cohort study in Jiangsu Province is recruiting patients with chronic hepatitis B infection to observe outcomes i…
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CLINICAL_TRIALS research · 2017-03-28Clinical Trial Update: Empowering Immigrants in the Greater Boston Area to Connect to HBV Care
This clinical trial update from Massachusetts General Hospital describes efforts to help immigrants in the Greater Boston area connect to he…
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CLINICAL_TRIALS research · 2017-01-25Clinical Trial Update: Establishment of Retrospective and Prospective Multicenter Cohort for Chronic Hepatitis B
A multicenter retrospective and prospective cohort study for chronic hepatitis B was established, combining historical and new patient data.…
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CLINICAL_TRIALS research · 2017-01-12Clinical Trial Update: The Study of Two Different Chinese Traditional Medicine Treatment on Chronic Hepatitis B [NA]
This entry reports a clinical trial evaluating two different Chinese traditional medicine treatments for chronic hepatitis B, sponsored by X…
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CLINICAL_TRIALS research · 2017-01-10Clinical Trial Update: Prophylactic Use of Entecavir for HBsAg Positive Lymphoma Patients Treated With Rituximab-based Immunochemotherapy [Phase 4]
Phase 4 clinical trial investigates prophylactic entecavir to prevent hepatitis B reactivation in HBsAg-positive lymphoma patients treated w…
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CLINICAL_TRIALS research · 2016-11-29Clinical Trial Update: REALM China Extension Study
A Chinese extension study for the REALM trial is underway for chronic hepatitis B, with the current status of the trial not disclosed.
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CLINICAL_TRIALS research · 2016-11-25Clinical Trial Update: Peginterferon Alfa-2b Treatment in HBeAg(+) Chronic Hepatitis b Patients Based on Interferon Gene Mutation and Receptor Detection [Phase 4]
Phase 4 clinical trial evaluating peginterferon alfa-2b for HBeAg-positive chronic hepatitis B, examining the impact of interferon gene muta…
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CLINICAL_TRIALS research · 2016-11-02Clinical Trial Update: A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis B
This is a completed retrospective biomarker study using stored samples from patients with chronic hepatitis B, sponsored by Hoffmann-La Roch…
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CLINICAL_TRIALS research · 2016-11-02Clinical Trial Update: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HbeAg-negative Chronic Hepatitis B (Perseas)
An observational study evaluating peginterferon alfa-2a (Pegasys) in patients with HBeAg-negative chronic hepatitis B has completed.
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CLINICAL_TRIALS research · 2016-11-02Clinical Trial Update: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Positive or HBeAg-Negative Chronic Hepatitis B
A completed observational study evaluated peginterferon alfa-2a (Pegasys) in patients with chronic hepatitis B, including both HBeAg-positiv…
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CLINICAL_TRIALS research · 2016-11-02Clinical Trial Update: A Follow-Up Study of Patients With HBeAg Positive Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML22265
This clinical trial update reports follow-up data for patients with HBeAg-positive chronic hepatitis B treated with Pegasys (peginterferon a…
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CLINICAL_TRIALS research · 2016-10-14Clinical Trial Update: Determinants of Virological Response After Discontinuation of Nucleoside Analogue Therapy in Hepatitis B Patients [NA]
Study investigating factors that influence virological response after stopping nucleoside analogue therapy in chronic hepatitis B patients.
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CLINICAL_TRIALS research · 2016-09-20Clinical Trial Update: A Study of the Interruption on the Mother-to-child Transmission of Hepatitis B Virus （HBV MTCT）in Newborns at High Risk
This clinical trial update describes a study evaluating strategies to interrupt mother-to-child transmission of hepatitis B virus in high-ri…
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CLINICAL_TRIALS research · 2016-09-20Clinical Trial Update: New Strategy Study of Functional Cure of Chronic Hepatitis B [NA]
This document provides an update on a clinical trial exploring a new strategy toward achieving a functional cure for chronic hepatitis B. Th…
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CLINICAL_TRIALS research · 2016-09-12Clinical Trial Update: A Study to Evaluate Addition of Peginterferon Alfa-2a to Chronic Hepatitis B (CHB) Patients Treated With NAs [Phase 4]
This Phase 4 clinical trial aims to evaluate adding peginterferon alfa-2a to chronic hepatitis B patients who are treated with nucleos(t)ide…
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CLINICAL_TRIALS research · 2016-08-15Clinical Trial Update: A Prospective Clinical Trial in Chronic Hepatitis B Patients NAs (Nucleotides or Nucleosides) Experienced (Anchor Study) [Phase 3]
A Phase 3 prospective trial in chronic hepatitis B patients who have prior exposure to nucleos(t)ide analogs (the anchor study) is sponsored…
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CLINICAL_TRIALS research · 2016-08-10Clinical Trial Update: Optimal Time for Tenofovir Treatment of Anti-Hepatitis B Virus (HBV) During the Pregnancy [NA]
This clinical trial update discusses the optimal timing of tenofovir treatment for chronic hepatitis B during pregnancy, with no results or …
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CLINICAL_TRIALS research · 2016-08-05Clinical Trial Update: RCT Study on Granulocyte Colony-stimulating Factor(G-CSF) Treatment of Hepatic Failure [Phase 4]
This clinical trial update reports a Phase 4 randomized study of granulocyte colony-stimulating factor (filgrastim) for hepatic failure, wit…
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CLINICAL_TRIALS research · 2016-06-29Clinical Trial Update: Follow-up Strategy of Chronic Hepatitis B for Early Detection and Diagnosis of Hepatocellular Carcinoma: A Randomized Control Trial
A randomized controlled trial evaluating follow-up strategies in chronic hepatitis B patients to enable earlier detection and diagnosis of h…
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CLINICAL_TRIALS research · 2016-06-21Clinical Trial Update: Liver Injury by Statins in Patients With History of Hepatitis B Virus Infection
This clinical trial update examines whether statin therapy is associated with liver injury in patients with a history of Hepatitis B infecti…
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CLINICAL_TRIALS research · 2016-06-08Clinical Trial Update: Prophylactic Treatment of Hepatic Dysplastic Nodules in HBsAg Positive Patients [NA]
Clinical trial update regarding prophylactic treatment for hepatic dysplastic nodules in HBsAg-positive patients; the current trial status i…
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CLINICAL_TRIALS research · 2016-02-08Clinical Trial Update: A Study to Characterise Immune Responses Following Immunisations With "Fendrix" or "Engerix B" Hepatitis B Vaccines [NA]
This clinical trial update describes a study to characterize immune responses after immunisation with two Hepatitis B vaccines, Fendrix and …