Records containing: Hepatic Insufficiency
This is the wording recorded or indexed by the source. An agency index term is not necessarily an authorised indication. Co-listed drug names are not linked to this term as a treatment relationship.
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CLINICAL_TRIALS study record update · 2024-01-11Study To Evaluate The Pharmacokinetics Of Jaktinib Hydrochloride Tablets In Subjects With Hepatic Impairment And Normal Hepatic Function
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CLINICAL_TRIALS study record update · 2023-12-20Phase I Clinical Study to Evaluate the Pharmacokinetics, Pharmacokinetics, and Safety of Intravenous Administration of Methoxyethyl Etomidate Hydrochloride for Injection in Subjects With Mild, Moderate, and Normal Hepatic Dysfunction.
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CLINICAL_TRIALS study record update · 2023-12-01A Pharmacokinetic Study to Assess Nevirapine Levels in HIV-infected Patients With Impaired Hepatic Function
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CLINICAL_TRIALS study record update · 2023-07-07Retrospective Chart Review to Evaluate the Safety Profile of Ceftobiprole in Patients With Impaired Hepatic or Renal Function or Immunosuppression
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CLINICAL_TRIALS study record update · 2023-03-24A Single Dose Pharmacokinetic Study of Tirzepatide in Subjects With Varying Degrees of Hepatic Impairment
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CLINICAL_TRIALS study record update · 2022-03-29Mitochondrial Function in Patients With Severe Liver Disease
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CLINICAL_TRIALS study record update · 2021-09-22A Single Dose Pharmacokinetic Study of LY2140023 in Subjects With Hepatic Impairment
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CLINICAL_TRIALS study record update · 2021-09-10A Phase 1, Open-Label, Single-Dose Study to Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite (ACP-5862)
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CLINICAL_TRIALS study record update · 2021-06-10Randomized, Double-blind, Placebo-controlled Trial to Investigate Safety, Tolerability, and Pharmacokinetics of Multiple Rising Oral Doses of BI 685509 Over 28 Days in Patients With Mild and Moderate Hepatic Impairment and of Single Oral BI 685509 Dose Compared to Healthy Volunteers
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CLINICAL_TRIALS study record update · 2021-04-30A 2-Part, Open-Label, Single-Dose Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of ACP-196
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CLINICAL_TRIALS study record update · 2020-12-21An Open-label, Single-dose Study to Assess the Pharmacokinetics of Oral Everolimus (Afinitor®) in Subjects With Impaired Hepatic Function
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CLINICAL_TRIALS study record update · 2020-09-18A 12-Week, Single-Blind, Placebo-Controlled, Randomized Study to Evaluate the Safety, Tolerability, and Physiological Regulation of an Amino Acid Food Product, AXA1665, in Subjects With Mild and Moderate Hepatic Insufficiency
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CLINICAL_TRIALS study record update · 2020-05-21An Observational Follow-on Study to Describe the Pharmacogenetics of the CC-90007-CP-003 Study Cohort
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CLINICAL_TRIALS study record update · 2020-05-21Hypercoagulability and Liver Function After Major Liver Resection
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CLINICAL_TRIALS study record update · 2019-11-18A Phase 1, Open-Label, Single-Dose Study to Evaluate the Pharmacokinetics and Safety of Ipatasertib in Subjects With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Subjects
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CLINICAL_TRIALS study record update · 2019-11-13An Open-Label Study to Investigate the Single-Dose Pharmacokinetics of MK-3866 When Administered to Subjects With Moderate and Severe Hepatic Impairment
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CLINICAL_TRIALS study record update · 2019-01-22A Single-Dose Pharmacokinetic Study of Abemaciclib (LY2835219) in Subjects With Varying Degrees of Hepatic Impairment
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CLINICAL_TRIALS study record update · 2019-01-07A Phase I, Non-randomized, Open-label, Single-dose Study to Investigate the Pharmacokinetics, Safety and Tolerability of BAY 1841788 (ODM-201) in Male Subjects With Hepatic Impairment, Renal Impairment and Normal Hepatic and Renal Function
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CLINICAL_TRIALS study record update · 2018-10-19A Single Dose Pharmacokinetic Study of LY2605541 in Subjects With Hepatic Impairment
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CLINICAL_TRIALS study record update · 2018-10-12Pharmacokinetics of Evacetrapib (LY2484595) in Subjects With Hepatic Impairment
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CLINICAL_TRIALS study record update · 2018-09-24Clinical Pharmacology Study of FYU-981 for Subjects With Hepatic Insufficiency
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CLINICAL_TRIALS study record update · 2018-04-03Metabolic Preconditioning Using Intravenous Dextrose: a Novel Strategy to Improve Hepatic Function After Liver Resection
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CLINICAL_TRIALS study record update · 2017-10-27Single Dose Study to Investigate the Pharmacokinetics of Odanacatib (MK-0822) in Subjects With Hepatic Insufficiency
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CLINICAL_TRIALS study record update · 2017-04-21A Pharmacokinetic Study of Baricitinib in Subjects With Hepatic Dysfunction
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CLINICAL_TRIALS study record update · 2016-11-18A Three-Part, Open-Label, Single-Dose Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of MK-8742