Heparin-induced Thrombocytopenia
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Sign up freeTop drugs studied for this disease
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FDA approval · 2015-03-23FDA Approved: ARGATROBAN — Original Application (Fresenius Kabi USA, LLC)
FDA approves Argatroban through an Original Application for Fresenius Kabi USA, marking a first-time approval of this injectable anticoagula…
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FDA approval · 2014-10-16FDA Approved: ARGATROBAN — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental NDA for Argatroban from Hikma Pharmaceuticals USA Inc., granting additional authorization under a supplemental a…
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FDA approval · 2014-06-30FDA Approved: ARGATROBAN — Original Application (Mylan Institutional LLC)
FDA approved a generic Argatroban from Mylan Institutional LLC under ANDA 202626 for use as an anticoagulant in adults with heparin-induced …
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FDA approval · 2014-06-30FDA Approved: ARGATROBAN — Original Application (Par Health USA, LLC)
The FDA approved a generic Argatroban product under an Original Application for Par Health USA, LLC.
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CLINICAL_TRIALS trial_result · 2013-09-10Clinical Trial Update: Heparin-Induced Thrombocytopenia Score Card Study [Phase 1]
A Phase 1 clinical trial update reports completion of the Heparin-Induced Thrombocytopenia Score Card study sponsored by McMaster University…
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CLINICAL_TRIALS trial_result · 2013-06-24Clinical Trial Update: Fondaparinux for the Treatment of Heparin-Induced Thrombocytopenia (HIT) [Phase 2]
Phase 2 clinical trial evaluating fondaparinux for treating heparin-induced thrombocytopenia has been terminated with results posted in 2013…
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CLINICAL_TRIALS trial_result · 2013-02-25Clinical Trial Update: Risk of Developing Antibodies to Heparin-PF4 After Heart Surgery
A completed clinical trial update evaluated the risk of developing antibodies to heparin-PF4 after heart surgery. This immune response is as…
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FDA approval · 2013-02-13FDA Approved: ARGATROBAN — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for Argatroban submitted by Hikma Pharmaceuticals USA Inc.
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CLINICAL_TRIALS trial_result · 2012-12-31Clinical Trial Update: A Comparative Sudy Comparing Argatroban® IV vs Desirudin SC for Suspected HIT With or Without Thrombosis Syndrome [Phase 4]
Phase 4 clinical trial comparing Argatroban intravenous versus Desirudin subcutaneous in suspected heparin-induced thrombocytopenia; the stu…
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CLINICAL_TRIALS research · 2012-11-27Clinical Trial Update: Heparin-Induced Thrombocytopenia: Development and Validation of a Predictive Clinical
This clinical trial update describes the development and validation of a predictive clinical model for identifying patients at risk of hepar…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients
This completed clinical trial evaluated management of heparin-induced thrombocytopenia in liver transplant recipients.
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CLINICAL_TRIALS trial_result · 2012-06-21Clinical Trial Update: Argatroban Versus Lepirudin in Critically Ill Patients [Phase 4]
A Phase 4 trial comparing Argatroban to Lepirudin in critically ill patients with heparin-induced thrombocytopenia has been terminated.
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CLINICAL_TRIALS trial_result · 2012-03-12Clinical Trial Update: Significance of Antibodies to Heparin/Platelet Factor 4 Complex in Vein Graft Patency and Potential Role of Argatroban for Prevention of Vein Graft Occlusion [Phase 4]
Phase 4 trial assessed the relevance of heparin/platelet factor 4 antibodies on vein graft patency after coronary bypass surgery and explore…
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FDA approval · 2012-01-05FDA Approved: ARGATROBAN — Original Application (Hikma Pharmaceuticals USA Inc.)
FDA approved Hikma Pharmaceuticals USA Inc.'s Argatroban on an Original Application, providing an injectable direct thrombin inhibitor for p…
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CLINICAL_TRIALS trial_result · 2011-12-06Clinical Trial Update: Pilot Dose Finding and Pharmacokinetic Study of Fondaparinux in Children With Thrombosis [Phase 1]
Phase 1 clinical trial assessing dose finding and pharmacokinetics of fondaparinux in pediatric patients with thrombosis, including cases of…
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CLINICAL_TRIALS trial_result · 2011-11-10Clinical Trial Update: Angiomax in Patients With HIT/HITTS Type II Undergoing CPB [Phase 3]
Phase 3 trial assessing Angiomax (bivalirudin) in patients with heparin-induced thrombocytopenia undergoing cardiopulmonary bypass has compl…
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CLINICAL_TRIALS trial_result · 2011-09-16Clinical Trial Update: Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning) [Phase 3]
Phase 3 trial update evaluating bivalirudin as anticoagulant therapy during percutaneous coronary intervention in patients with heparin-indu…
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CLINICAL_TRIALS trial_result · 2011-02-25Clinical Trial Update: Retrospective Registry of Patients With Acute Heparin-induced Thrombocytopenia Type II
A retrospective registry of patients with acute heparin-induced thrombocytopenia type II (HIT II) was completed, with results posted in 2011…
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CLINICAL_TRIALS research · 2010-04-15Clinical Trial Update: Generation of Heparin-induced Thrombocytopenia (HIT)-Antibodies Without Prior Heparin Exposure
An update on a study exploring the generation of heparin-induced thrombocytopenia antibodies in the absence of prior heparin exposure.
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CLINICAL_TRIALS trial_result · 2010-03-09Clinical Trial Update: Evaluating the Presence of Blood Clots in People With Heparin-Induced Thrombocytopenia (HIT) (The HOT Study)
The HOT study evaluated the presence of blood clots in people with heparin-induced thrombocytopenia. The trial was terminated and results we…
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CLINICAL_TRIALS research · 2009-07-27Clinical Trial Update: Validating 4Ts for Heparin Induced Thrombocytopenia (HIT)
Clinical trial update evaluating the 4Ts scoring system for diagnosing heparin-induced thrombocytopenia, sponsored by MedStar Health Researc…
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CLINICAL_TRIALS trial_result · 2009-03-02Clinical Trial Update: Heparin Induced Thrombocytopenia: Pharmacoeconomics
This completed clinical trial update reports on the pharmacoeconomic analysis and cost implications of managing heparin-induced thrombocytop…
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CLINICAL_TRIALS trial_result · 2008-11-13Clinical Trial Update: Efficacy and Safety Study of Argatroban to Treat Heparin-Induced Thrombocytopenia [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of Argatroban for treating heparin-induced thrombocytopenia has completed.
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CLINICAL_TRIALS trial_result · 2008-02-18Clinical Trial Update: Heparin-Induced Thrombocytopenia Registry
The Heparin-Induced Thrombocytopenia Registry sponsored by Brigham and Women's Hospital has completed. It collects and reports outcomes in p…
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CLINICAL_TRIALS trial_result · 2007-12-06Clinical Trial Update: Heparin Antibodies in Intensive Care Unit Patients (HAICU)
The HAICU trial update indicates that the study evaluating heparin antibodies in ICU patients with heparin-induced thrombocytopenia has comp…