Hematologic Malignancy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-02-26Clinical Trial Update: Early Neutropenic Fever De-escalation of Antibiotics Study [Phase 3]
Phase 3 trial exploring de-escalation of antibiotics for early neutropenic fever in hematologic malignancy.
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Tocilizumab for the Prevention of Graft Failure and GVHD in Haplo-Cord Transplantation [Phase 2]
Phase 2 clinical trial update evaluating tocilizumab for prevention of graft failure and graft-versus-host disease in haplo-cord transplanta…
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CLINICAL_TRIALS trial_result · 2023-05-06Clinical Trial Update: Expressive Helping for Stem Cell Transplant Patients [Phase 3]
A Phase 3 clinical trial update for Expressive Helping in stem cell transplant patients with hematologic malignancies; the study is complete…
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CLINICAL_TRIALS trial_result · 2023-04-19Clinical Trial Update: PROACTIVE: Preventing Acute/Chronic GVHD With TocIlizumab Combined With GVHD Prophylaxis Post allogEneic Transplant [Phase 2]
Phase 2 trial updating the use of tocilizumab with GVHD prophylaxis to prevent acute and chronic GVHD after allogeneic stem cell transplant;…
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CLINICAL_TRIALS trial_result · 2023-02-21Clinical Trial Update: A Long-term, Continued Treatment and Follow-up Study in Participants With Hematologic Malignancies Treated With Duvelisib (IPI-145) [Phase 2]
Phase 2 long-term follow-up study of duvelisib (IPI-145) in participants with hematologic malignancies; status completed with results posted…
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CLINICAL_TRIALS trial_result · 2022-10-19Clinical Trial Update: Ruxolitinib for Newly Diagnosed Bronchiolitis Obliterans Syndrome [Phase 2]
Phase 2 trial update on ruxolitinib for newly diagnosed bronchiolitis obliterans syndrome with hematologic malignancy.
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CLINICAL_TRIALS trial_result · 2022-07-19Clinical Trial Update: Patient-Centered Care for the Older Adult With Hematologic Malignancy [NA]
Clinical trial update on patient-centered care for older adults with hematologic malignancy; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-05-10Clinical Trial Update: Ex Vivo TCR αβ T Cell Depletion for Graft-Versus-Host Disease Prophylaxis in Mismatched Donor Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies [Phase 2]
Phase 2 clinical trial exploring ex vivo TCR αβ T cell depletion to prevent graft-versus-host disease after mismatched donor peripheral bloo…
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CLINICAL_TRIALS trial_result · 2022-03-15Clinical Trial Update: Ex Vivo Expanded NK Cells Infusion Decrease Relapse Post Hematopoietic Stem Cell Transplantation [Phase 1, Phase 2]
Early-phase trial investigating ex vivo expanded NK cell infusion to reduce relapse after hematopoietic stem cell transplantation in hematol…
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CLINICAL_TRIALS trial_result · 2022-01-19Clinical Trial Update: A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients [NA]
Completed proof-of-concept trial evaluated a positive psychology intervention for patients undergoing allogeneic stem cell transplantation f…
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: Comparison of PT-Cy at a Dose of 25 mg/kg/Day and PT-Cy at a Dose of 50 mg/kg/Day in GVHD Prophylaxis [Phase 3]
Phase 3 trial comparing two doses of post-transplant cyclophosphamide (PT-Cy) for graft-versus-host disease prophylaxis; status not disclose…
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CLINICAL_TRIALS trial_result · 2021-12-23Clinical Trial Update: Infusion of Donor Derived Cytokine Induced Killer (CIK) Cells in Hematological Patients Relapsed After Haploidentical Stem Cell Transplant [Phase 1, Phase 2]
Phase 1/2 trial evaluating infusion of donor-derived cytokine-induced killer (CIK) cells in patients with relapsed hematologic malignancies …
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CLINICAL_TRIALS trial_result · 2021-10-27Clinical Trial Update: Venetoclax Combining With Fludarabine and Melphalan as Conditioning Regimen for Allo-HSCT [Phase 2]
Phase 2 trial evaluating venetoclax with fludarabine and melphalan as a conditioning regimen for allogeneic hematopoietic stem cell transpla…
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CLINICAL_TRIALS trial_result · 2021-06-04Clinical Trial Update: Tocilizumab for Patients With Cancer and COVID-19 Disease [Phase 2]
Phase 2 trial evaluating tocilizumab in cancer patients with COVID-19 was terminated; results were posted in June 2021.
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CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: Testing Trametinib as a Potential Targeted Treatment in Cancers With BRAF Genetic Changes (MATCH-Subprotocol R) [Phase 2]
The National Cancer Institute’s MATCH subprotocol R Phase 2 trial is evaluating trametinib as a targeted therapy for cancers with BRAF genet…
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CLINICAL_TRIALS trial_result · 2021-02-05Clinical Trial Update: Testing Ado-Trastuzumab Emtansine as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol Q) [Phase 2]
A Phase 2 MATCH-subprotocol Q trial evaluating ado-trastuzumab emtansine (T-DM1) for cancers with HER2 genetic changes; results were posted …
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CLINICAL_TRIALS trial_result · 2021-01-11Clinical Trial Update: Phase II Maraviroc for GVHD Prevention [Phase 2]
A Phase II clinical trial evaluating maraviroc for prevention of graft-versus-host disease (GVHD) in hematologic malignancy patients has com…
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Fungal Prophylaxis With Isavuconazole for Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant (HCT) [Phase 2]
Phase 2 trial evaluating fungal prophylaxis with isavuconazole in patients undergoing allogeneic hematopoietic stem cell transplantation; th…
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CLINICAL_TRIALS trial_result · 2020-03-06Clinical Trial Update: Entospletinib (ENTO) as Monotherapy and in Combination With Chemotherapy in Japanese Adults [Phase 1]
Phase 1 trial updates Entospletinib as monotherapy and in combination with chemotherapy in Japanese adults with hematologic malignancies, in…
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CLINICAL_TRIALS trial_result · 2020-01-29Clinical Trial Update: Efficacy of Prophylactic Low Level Laser Therapy (LLLT) Performed by Nurses for Decreasing Severity of Oral Mucositis During Hematopoietic Stem Cell (HSC) Transplantation [Phase 3]
Phase 3 trial investigating prophylactic low level laser therapy administered by nurses to reduce oral mucositis severity in hematopoietic s…
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CLINICAL_TRIALS trial_result · 2019-08-05Clinical Trial Update: Expanded Cord Blood in Patients in Need of an Allogeneic Stem Cell Transplant [Phase 1, Phase 2]
A Phase 1/2 clinical trial update on expanded cord blood use for patients requiring an allogeneic stem cell transplant has been completed.
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CLINICAL_TRIALS trial_result · 2018-06-11Clinical Trial Update: Non Invasive Optical Imaging of WBC Count [NA]
Massachusetts General Hospital conducted a clinical trial to evaluate non-invasive optical imaging for measuring white blood cell counts in …
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Study of a Reduced-toxicity Myeloablative Conditioning Regimen Using Fludarabine and Full Doses of Intravenous Busulfan in Pediatric Patients Not Eligible for Standard Myeloablative Conditioning Regimens [Phase 2]
Phase 2 study in pediatric patients ineligible for standard myeloablative conditioning evaluated a reduced-toxicity conditioning regimen wit…
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen [Phase 2]
Phase 2 trial investigating combined T cell depleted haploidentical peripheral blood stem cell and unrelated umbilical cord blood transplant…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Iron Overload in Patients Undergoing Donor Stem Cell Transplant
This clinical trial status update reports completion of a study examining iron overload in patients undergoing donor hematopoietic stem cell…