Hematologic Diseases
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CLINICAL_TRIALS trial_result · 2021-09-23Clinical Trial Update: Sirolimus & Mycophenolate Mofetil as GVHD Prophylaxis in Myeloablative, Matched Related Donor HCT [Phase 2]
Phase 2 trial evaluating sirolimus and mycophenolate mofetil for GVHD prophylaxis in myeloablative matched related donor hematopoietic cell …
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CLINICAL_TRIALS trial_result · 2020-05-06Clinical Trial Update: Prospective Study of Patients With Thrombocytopenia Following HSCT [Phase 3]
Phase 3 clinical trial update for thrombocytopenia after hematopoietic stem cell transplantation has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: Comparison of Multigam IV (5% vs. 10%) in Patients With an Immunodeficiency Secondary to a Hematological Disorder
A completed clinical trial comparing 5% vs 10% Multigam IV in patients with immunodeficiency due to a hematologic disorder; results posted i…
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CLINICAL_TRIALS trial_result · 2018-12-24Clinical Trial Update: Clinical Use of Pathogen Reduced Red Blood Cell Suspension [Phase 3]
Phase 3 trial update on the clinical use of pathogen-reduced red blood cell suspension has completed.
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CLINICAL_TRIALS research · 2018-08-10Clinical Trial Update: A Dose Finding Study of Remifentanil and Propofol for Lumbar Punctures in Children [Phase 1, Phase 2]
A dose-finding study evaluating remifentanil and propofol for lumbar punctures in children across Phase 1 and Phase 2, with completed status…
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: Dose-escalation Trial of the Safety, Pharmacokinetics, and Pharmacodynamics of Iron Isomaltoside (Monofer®) [Phase 1]
A Phase 1 dose-escalation trial evaluating the safety, pharmacokinetics, and pharmacodynamics of iron isomaltoside (Monofer) in individuals …
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: Evaluation of a Kit for the Prediction of the Risk of Graft Versus Host Disease [NA]
A clinical trial evaluating a predictive kit for graft-versus-host disease in hematologic diseases has been terminated.
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CLINICAL_TRIALS research · 2017-08-08Clinical Trial Update: Sequential Analysis in Patients With an Hemopathy [NA]
This document provides an update on a sequential analysis clinical trial in patients with a hematologic condition (hemopathy); the trial sta…
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CLINICAL_TRIALS research · 2017-04-06Clinical Trial Update: Prevalence of Replication of Human Herpes Virus 6 (HHV6) in Blood and Skin During Exanthemia, in Patients With Hemopathy. Is There a Correlation With the Etiology of the Exanthema?
An update on a clinical trial from Centre Hospitalier Universitaire Amiens examining the prevalence of HHV-6 replication in blood and skin d…
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CLINICAL_TRIALS trial_result · 2016-08-30Clinical Trial Update: Daily Ginger Drinking and Platelet Function [NA]
A completed clinical trial investigated daily ginger consumption and its effect on platelet function.
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CLINICAL_TRIALS trial_result · 2016-06-21Clinical Trial Update: Efficacy of Biosimilar Filgrastim on the Mobilization of Hematopoietic Stem Cell CD34+ (Cluster of Differentiation 34) and on the Kinetic Engraftment
This clinical trial update reports on the efficacy of a biosimilar filgrastim for mobilizing CD34+ hematopoietic stem cells and its impact o…
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CLINICAL_TRIALS trial_result · 2014-12-08Clinical Trial Update: Micafungin Versus Intravenous Itraconazole as Empirical Antifungal Therapy for Febrile Neutropenic Patients With Hematological Diseases [Phase 2]
A Phase 2 trial update comparing micafungin to intravenous itraconazole as empirical antifungal therapy in febrile neutropenia patients with…
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CLINICAL_TRIALS research · 2014-09-16Clinical Trial Update: MSCs With or Without Peripheral Blood Stem Cell for Treatment of Poor Graft Function and Delayed Platelet Engraftment [Phase 2, Phase 3]
This ClinicalTrials.gov entry describes a Phase 2/Phase 3 trial evaluating mesenchymal stem cells with or without peripheral blood stem cell…
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CLINICAL_TRIALS trial_result · 2014-08-28Clinical Trial Update: Safety and Effectiveness of Two Blood Transfusion Strategies in Surgical Patients With Cardiovascular Disease [Phase 3]
Phase 3 clinical trial update comparing two blood transfusion strategies in surgical patients with cardiovascular disease; results posted in…
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CLINICAL_TRIALS trial_result · 2014-08-19Clinical Trial Update: Granulocyte Colony Stimulating Factor (G-CSF) for Bone Marrow Transplant (BMT) [NA]
A completed clinical trial evaluated granulocyte colony-stimulating factor (filgrastim) in the bone marrow transplant setting, with results …
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CLINICAL_TRIALS research · 2014-07-14Clinical Trial Update: Patient-Reported Outcomes Version of Common Terminology Criteria (CTCPRO) Cognitive Debriefing
This update reports progress on cognitive debriefing for CTCPRO, a patient-reported outcomes version of CTCAE used to assess cancer-related …
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CLINICAL_TRIALS trial_result · 2014-04-28Clinical Trial Update: T-Cell Depletion and Stem Cell Transplant for Immune Deficiencies and Histiocytic Disorders [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating T-cell depletion and stem cell transplantation for immune deficiencies and histiocytic disorders has bee…
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CLINICAL_TRIALS trial_result · 2013-06-20Clinical Trial Update: Dose-ranging Study of a Single Administration of T-cell Add-back Depleted of Host Alloreactive Cells in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical Donor [Phase 1, Phase 2]
Completed Phase 1/2 dose-ranging trial evaluating a T-cell add-back product depleted of host alloreactive cells in patients receiving haploi…
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CLINICAL_TRIALS research · 2013-01-16Clinical Trial Update: Mesenchymal Stem Cells Combined With Cord Blood for Treatment of Graft Failure [Phase 2]
Phase 2 clinical trial update from Nanfang Hospital/Southern Medical University evaluating mesenchymal stem cells combined with umbilical co…
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CLINICAL_TRIALS research · 2013-01-16Clinical Trial Update: Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating mesenchymal stem cells for treating poor graft function after an allogeneic hematopoietic stem cell transp…
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CLINICAL_TRIALS research · 2012-11-09Clinical Trial Update: Effect of the Use of Simulation (Video) on the Oral Hygiene [NA]
An update on a University of Sao Paulo trial evaluating the impact of simulation videos on oral hygiene in participants with hematologic dis…
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CLINICAL_TRIALS research · 2012-09-12Clinical Trial Update: Registry of Febrile Neutropenia and Invasive Fungal Infections
This entry describes an ongoing registry tracking febrile neutropenia and invasive fungal infections in patients with hematologic diseases.
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CLINICAL_TRIALS research · 2012-03-05Clinical Trial Update: A Study of Co-infections of HIV-1 and Schistosoma Mansoni and Its Impact on Praziquantel Treatment Outcomes [NA]
This Clinical Trial Update examines co-infections of HIV-1 and Schistosoma mansoni and how they influence praziquantel treatment outcomes.
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CLINICAL_TRIALS trial_result · 2010-07-09Clinical Trial Update: Benefit of SeptiFast Multiplex PCR in the Etiologic Diagnosis and Therapeutic Approach for Onco-hematology Patients Presenting Sepsis
A completed trial evaluated the use of SeptiFast multiplex PCR to identify the cause of sepsis in patients with hematologic diseases and to …
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CLINICAL_TRIALS research · 2009-12-23Clinical Trial Update: Exercise During Chemotherapy for Patients With Hematological Malignancies [Phase 3]
Phase 3 clinical trial evaluating exercise during chemotherapy for hematologic diseases and hematologic malignancies; current status is unkn…