Heart Transplantation
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Efficacy and Safety of Enteric-coated Mycophenolate Sodium in Heart Transplant Recipients [Phase 3]
A Phase 3 clinical trial evaluated the efficacy and safety of enteric-coated mycophenolate sodium in heart transplant recipients; the study …
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: A Study of Safety, Tolerability & Efficacy of Certican in de Novo Heart Transplant (Tx) Patients [Phase 3]
Phase 3 trial evaluating safety, tolerability, and efficacy of Certican in de novo heart transplantation patients has completed.
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Renal Safety of Everolimus in Addition to Cyclosporine Microemulsion in Cardiac Transplant Recipients. [Phase 3]
Phase 3 trial evaluating renal safety of adding everolimus to cyclosporine in heart transplant recipients has completed.
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Everolimus Versus Mycophenolate Mofetil in Combination With Reduced Dose Cyclosporine Microemulsion in Maintenance Heart Transplant Recipients [Phase 4]
A Phase 4 trial comparing everolimus versus mycophenolate mofetil, both with reduced-dose cyclosporine microemulsion, as maintenance therapy…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: Heart Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Heart Transplant Recipients [Phase 4]
Phase 4 trial in heart transplant recipients evaluating CellCept (mycophenolate mofetil) with Rapamune (sirolimus) was terminated.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of Daclizumab (Zenapax) in Combination With Mycophenolate Mofetil (CellCept) and Sirolimus in Prevention of Acute Rejection in Heart Transplant Participants [Phase 4]
Phase 4 clinical trial assessing daclizumab with mycophenolate mofetil and sirolimus to prevent acute rejection in heart transplant recipien…
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CLINICAL_TRIALS trial_result · 2016-09-15Clinical Trial Update: Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation [Phase 2, Phase 3]
A Phase 2/3 trial comparing zoledronic acid to alendronate for prevention of bone loss after organ transplantation has completed with result…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Thymic Tolerance in Pediatric Heart Transplantation [Phase 2]
A Phase 2 clinical trial evaluating thymic tolerance in pediatric heart transplantation has been terminated.
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CLINICAL_TRIALS trial_result · 2016-06-13Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Zenapax in Combination With CellCept, Cyclosporine, and Corticosteroids in Patients Undergoing Cardiac Transplantation [Phase 4]
A Phase 4 clinical trial assessing the efficacy and safety of Zenapax in combination with CellCept, cyclosporine, and corticosteroids in hea…
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CLINICAL_TRIALS trial_result · 2016-05-25Clinical Trial Update: Pharmacokinetics of Mmf and Valganciclovir [Phase 4]
Phase 4 pharmacokinetic study of mycophenolate mofetil and valganciclovir in kidney and heart transplant recipients has completed.
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CLINICAL_TRIALS trial_result · 2016-03-15Clinical Trial Update: Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant [Phase 3]
Phase 3 trial evaluating long-term safety and efficacy of prolonged-release tacrolimus (FK506E-MR4) in transplant recipients when used with …
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CLINICAL_TRIALS trial_result · 2016-01-01Clinical Trial Update: Noninvasive Methods to Monitor Graft Survival in Heart Transplant Patients
A completed clinical trial from NIAID evaluating noninvasive methods to monitor graft survival in heart transplant patients.
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CLINICAL_TRIALS trial_result · 2015-06-16Clinical Trial Update: Study to Compare the Pharmacokinetics of Tacrolimus in Adult Transplant Recipients Treated With Advagraf® or Prograf® [Phase 2]
A Phase 2 study comparing tacrolimus pharmacokinetics in adult heart, lung, and pancreas transplant recipients treated with Advagraf vs Prog…
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Safety Outcomes of Lower Immunosuppression Versus Traditional Immunosuppression in Heart Transplant Recipients [Phase 4]
Phase 4 study comparing lower immunosuppression versus traditional immunosuppression in heart transplant recipients to evaluate safety outco…
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CLINICAL_TRIALS trial_result · 2014-10-29Clinical Trial Update: A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Heart Transplant Patients. [Phase 3]
A Phase 3 trial evaluating CellCept (mycophenolate mofetil) in combination therapy for heart transplant patients has completed, with results…
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CLINICAL_TRIALS trial_result · 2014-05-13Clinical Trial Update: SCHEDULE - Scandinavian Heart Transplant Everolimus de Novo Study With Early Calcineurin Inhibitor (CNI) Avoidance [Phase 4]
Phase 4 update on the SCHEDULE trial evaluating de novo everolimus with early calcineurin inhibitor avoidance in heart transplant recipients…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival
This completed clinical trial from NIAID examined how donor and recipient genetic expression influences survival after heart, lung, liver, a…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: Effect of Exercise After Heart Transplantation [Phase 2]
A Phase 2 clinical trial evaluating the effects of an exercise program after heart transplantation has completed.
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CLINICAL_TRIALS trial_result · 2013-01-04Clinical Trial Update: Study on Heart Rate Variability in Cardiac Transplant Recipients With Exercise and After Exercise Training [NA]
A completed clinical trial, sponsored by National Taiwan University Hospital, evaluating heart rate variability in heart transplant recipien…
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CLINICAL_TRIALS trial_result · 2011-11-02Clinical Trial Update: Efficacy and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in Comparison to Mycophenolate Mofetil (MMF) in de Nove Heart Patients [Phase 4]
A Phase 4 study compares enteric-coated mycophenolate sodium with mycophenolate mofetil in de novo heart transplant patients, evaluating eff…
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CLINICAL_TRIALS trial_result · 2011-05-23Clinical Trial Update: Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients [Phase 4]
Phase 4 study assessing safety and efficacy of converting from a calcineurin inhibitor to sirolimus in renally impaired heart transplant rec…
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CLINICAL_TRIALS trial_result · 2011-04-18Clinical Trial Update: Nordic Everolimus (Certican) Trial in Heart and Lung Transplantation [Phase 4]
Phase 4 clinical trial update for everolimus (Certican) in heart and lung transplantation; study completed with results posted in 2011.
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CLINICAL_TRIALS trial_result · 2011-02-21Clinical Trial Update: Canadian Cardiology de Novo Study: A Comparison Between Tacrolimus- and Cyclosporine- Based Immunoprophylactic Regimens [Phase 3]
A Phase 3 trial comparing tacrolimus- and cyclosporine-based immunoprophylaxis regimens in heart transplant recipients has completed with re…
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CLINICAL_TRIALS trial_result · 2010-01-12Clinical Trial Update: Shift to Everolimus (RAD) Kidney Sparing Study [Phase 4]
A Phase 4 kidney-sparing study evaluating Everolimus (RAD) for patients with kidney dysfunction in the context of heart transplantation has …
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CLINICAL_TRIALS trial_result · 2009-02-16Clinical Trial Update: Exchange of Azathioprine by Mycophenolatmofetile and Cyclosporine A Dose Reduction After Heart Transplantation [NA]
This clinical trial evaluates exchanging azathioprine for mycophenolate mofetil and reducing cyclosporine A dose after heart transplantation…