Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-03-25Clinical Trial Update: Optimising Pacemaker Therapy for Contractility [Phase 2]
Phase 2 clinical trial update on optimising pacemaker therapy for contractility in chronic heart failure has completed.
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FDA approval · 2020-03-24FDA Approved: MILRINONE LACTATE — Original Application (Meitheal Pharmaceuticals Inc.)
FDA approved milrinone lactate from Meitheal Pharmaceuticals as an original application (ANDA) approval for a generic milrinone lactate prod…
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CLINICAL_TRIALS trial_result · 2020-03-20Clinical Trial Update: Statin Therapy in Heart Failure: Potential Mechanisms of Benefit [Phase 4]
Phase 4 trial update exploring potential mechanisms of benefit of statin therapy in heart failure; completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: PCORI-1310-06998 Trial of a Decision Support Intervention for Patients and Caregivers Offered Destination Therapy Heart Assist Device [NA]
Clinical trial update for a decision support intervention related to destination therapy heart assist device showed completed status with re…
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CLINICAL_TRIALS trial_result · 2020-03-17Clinical Trial Update: ICMNC-HF. IntraCoronary Bone Marrow MonoNuclear Cells in Heart Failure (HF) Patients [Phase 1, Phase 2]
Clinical trial update for ICMNC-HF, investigating intra-coronary bone marrow mononuclear cells in heart failure patients (Phase 1/Phase 2). …
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CLINICAL_TRIALS trial_result · 2020-03-13Clinical Trial Update: Stem Cell Therapy in Patients With Severe Heart Failure & Undergoing Left Ventricular Assist Device Placement [Phase 1, Phase 2]
Phase 1/2 trial assessing stem cell therapy in patients with severe heart failure undergoing left ventricular assist device placement has co…
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CLINICAL_TRIALS withdrawal · 2020-03-13Clinical Trial Update: Effect of Ivabradine and Beta-blockers Combination Versus Beta-blockers Up-titration on Right Ventricular Pacing [Phase 4]
A Phase 4 clinical trial evaluating the effect of ivabradine with beta-blocker combination versus beta-blocker up-titration in heart rate co…
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FDA approval · 2020-03-11FDA Approved: CARVEDILOL — Supplemental Application (Advagen Pharma Ltd)
FDA approved a supplemental application for carvedilol (Advagen Pharma Ltd) under an ANDA, authorizing a supplemental approval for this gene…
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
A completed clinical trial assessing the implementation of a national point-of-care ultrasound training program and its effects on various a…
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: A Phase II Dose-escalation Study to Assess the Feasibility and Safety of Transendocardial Delivery of Three Different Doses of Allogeneic Mesenchymal Precursor Cells (MPCs)in Subjects With Heart Failure [Phase 2]
Phase II dose-escalation study evaluating Feasibility and Safety of transendocardial delivery of allogeneic MPCs in subjects with heart fail…
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: Safety of Body Composition Analysis in Heart Failure Patients With Implantable Cardioverter Defibrillators (ICDs) [NA]
A completed clinical trial evaluating the safety of body composition analysis in heart failure patients with ICDs has posted results.
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CLINICAL_TRIALS trial_result · 2020-03-09Clinical Trial Update: Treatment of Sleep Disordered Breathing In Acute Decompensated Heart Failure Patients [Phase 4]
Phase 4 trial update on treating sleep disordered breathing in patients with acute decompensated heart failure has completed with results po…
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CLINICAL_TRIALS trial_result · 2020-03-04Clinical Trial Update: A Study of CLR325 in Chronic Stable Heart Failure Patients. [Phase 2]
Phase 2 trial update for CLR325 in chronic stable heart failure has completed with results posted.
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FDA approval · 2020-03-03FDA Approved: CAPTOPRIL — Supplemental Application (Camber Pharmaceuticals, Inc.)
FDA approved a supplemental application for CAPTOPRIL by Camber Pharmaceuticals, granting approval of an additional generic captopril produc…
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FDA approval · 2020-03-03FDA Approved: CAPTOPRIL — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for CAPTOPRIL (captopril) from Hikma Pharmaceuticals USA Inc. under an ANDA. The action concerns…
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: Sodium-glucose Co-transporter 2 Inhibitors Effects in Failing Heart Patients [Phase 4]
Phase 4 trial update evaluating SGLT2 inhibitors in patients with diabetes and heart failure, including potential effects on ventricular arr…
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FDA approval · 2020-03-03FDA Approved: CARVEDILOL — Supplemental Application (Quallent Pharmaceuticals Health LLC)
FDA approves a supplemental application for carvedilol from Quallent Pharmaceuticals Health LLC, approving an updated generic product.
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FDA approval · 2020-03-02FDA Approved: CARVEDILOL — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for carvedilol from Teva Pharmaceuticals USA, resulting in updated labeling. The approval confirms c…
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CLINICAL_TRIALS trial_result · 2020-02-26Clinical Trial Update: Compare the Effects of Single Versus Repeated Intracoronary Application of Autologous Bone Marrow-derived Mononuclear Cells on Mortality in Patients With Chronic Post-infarction Heart Failure [Phase 2, Phase 3]
A clinical trial comparing single versus repeated intracoronary autologous bone marrow–derived mononuclear cell therapy in chronic post-infa…
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CLINICAL_TRIALS trial_result · 2020-02-26Clinical Trial Update: Zepatier For Treatment Of Hepatitis C-Negative Patients Who Receive Heart Transplants From Hepatitis C-Positive Donors (HCV) [Phase 1, Phase 2]
Clinical trial update for Zepatier in hepatitis C-negative patients receiving heart transplants from hepatitis C-positive donors; completed …
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CLINICAL_TRIALS trial_result · 2020-02-25Clinical Trial Update: Investigation of the Safety and Feasibility of AAV1/SERCA2a Gene Transfer in Patients With Chronic Heart Failure [Phase 2]
Phase 2 trial investigating AAV1/SERCA2a gene transfer in chronic heart failure was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-19Clinical Trial Update: Effects of Empagliflozin on Clinical Outcomes in Patients With Acute Decompensated Heart Failure [Phase 2]
Phase 2 trial assessing the effects of empagliflozin on outcomes in patients with acute decompensated heart failure; results posted after co…
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FDA approval · 2020-02-19FDA Approved: ETHACRYNIC ACID — Original Application (Upsher-Smith Laboratories, LLC)
FDA approved Upsher-Smith's original generic application for Ethacrynic acid, a loop diuretic.
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CLINICAL_TRIALS trial_result · 2020-02-17Clinical Trial Update: Pulmonary Artery Pressure Reduction With ENTresto (Sacubitril/Valsartan) [Phase 4]
A Phase 4 trial update on reducing pulmonary artery pressure with sacubitril/valsartan (ENTresto) in congestive heart failure was terminated…
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CLINICAL_TRIALS trial_result · 2020-02-17Clinical Trial Update: Interleukin-1 Receptor Antagonist for the Treatment of Heart Failure in Patients With Left Ventricular Assist Devices [Phase 1, Phase 2]
This clinical trial update reports on Phase 1/2 testing of an interleukin-1 receptor antagonist for heart failure in patients with left vent…