Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: His Bundle Pacing Versus Coronary Sinus Pacing for Cardiac Resynchronization Therapy [NA]
Trial comparing His bundle pacing to coronary sinus pacing for cardiac resynchronization therapy has completed with posted results.
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FDA approval · 2021-08-10FDA Approved: ENALAPRIL MALEATE ORAL SOLUTION — Original Application (Bionpharma Inc.)
FDA approved ENALAPRIL MALEATE ORAL SOLUTION from Bionpharma Inc. under Original Application ANDA212408.
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CLINICAL_TRIALS trial_result · 2021-08-06Clinical Trial Update: Hemodynamically Guided Home Self-Therapy in Severe Heart Failure Patients (HOMEOSTASIS) [NA]
Clinical trial update for the HOMEOSTASIS study investigating hemodynamically guided home self-therapy in severe heart failure patients; sta…
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FDA approval · 2021-08-05FDA Approved: ENALAPRIL MALEATE — Supplemental Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
FDA approved a supplemental application for enalaprilate maleate from Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effecti…
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CLINICAL_TRIALS trial_result · 2021-08-05Clinical Trial Update: Efficacy and Safety Trial of OPC-61815 Injection Compared With Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure [Phase 3]
Phase 3 trial comparing OPC-61815 injection to tolvaptan in congestive heart failure completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-08-05Clinical Trial Update: Comparing Rate Response With CLS Versus Accelerometer ICD Settings in Heart Failure Patients With BIOTRONIK CRT-Ds [NA]
A completed clinical trial comparing rate response settings in BIOTRONIK CRT-D devices for heart failure patients, with results posted.
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FDA approval · 2021-08-04FDA Approved: CORLANOR — Supplemental Application (Amgen Inc)
The FDA approved Amgen's supplemental application for CORLANOR (ivabradine).
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CLINICAL_TRIALS trial_result · 2021-08-04Clinical Trial Update: Ivabradine in Patients With Congestive Heart Failure [Phase 4]
Phase 4 trial update evaluating ivabradine in patients with congestive heart failure has been completed.
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CLINICAL_TRIALS trial_result · 2021-08-02Clinical Trial Update: Dapagliflozin on Hypotensive Heart Failure Patients After Sacubitril/Valsartan Therapy [Phase 4]
Phase 4 trial update evaluating dapagliflozin in hypotensive heart failure patients after sacubitril/valsartan therapy has completed.
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CLINICAL_TRIALS trial_result · 2021-07-28Clinical Trial Update: Clinical Pharmacology Trial to Investigate the Dose of OPC-61815 Injection Equivalent to Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure [NA]
Clinical pharmacology trial completed to determine the dose of OPC-61815 injection equivalent to tolvaptan 15 mg tablet in patients with con…
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CLINICAL_TRIALS trial_result · 2021-07-27Clinical Trial Update: Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF) [Phase 2]
Phase 2 trial assessing IV omecamtiv mecarbil for safety and efficacy in patients with left ventricular systolic dysfunction hospitalized fo…
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CLINICAL_TRIALS trial_result · 2021-07-19Clinical Trial Update: Safety and Tolerability Study of AZD4831 in Patients With Heart Failure. [Phase 2]
Phase 2 safety and tolerability study of AZD4831 in heart failure was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-07-19Clinical Trial Update: Early Management Strategies of Acute Heart Failure for Patients With NSTEMI [Phase 4]
Phase 4 clinical trial update investigating early management strategies for acute heart failure in patients with NSTEMI.
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CLINICAL_TRIALS trial_result · 2021-07-16Clinical Trial Update: Phase IIb Safety and Efficacy Study of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Moderate Chronic Kidney Disease Alone [Phase 2]
Phase IIb study evaluating BAY94-8862 for safety and efficacy in worsening chronic heart failure with left ventricular systolic dysfunction,…
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CLINICAL_TRIALS trial_result · 2021-07-16Clinical Trial Update: Effect of Levosimendan on miRNAs Regulation in the Failing Hearts [Phase 4]
Phase 4 clinical trial investigating the effect of levosimendan on microRNA regulation in patients with heart failure is ongoing with unknow…
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FDA approval · 2021-07-16FDA Approved: TOLVAPTAN — Original Application (Camber Pharmaceuticals, Inc.)
FDA approves Camber Pharmaceuticals' tolvaptan via an original (ANDA) application, indicating a generic tolvaptan product is approved.
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CLINICAL_TRIALS trial_result · 2021-07-14Clinical Trial Update: ASIAN HF Registry, A Prospective Observational Study
A completed prospective observational registry study on heart failure in Asia with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-07-13Clinical Trial Update: Efficacy of Omega-3 Fatty Acid Therapy in Preventing Gastrointestinal Bleeding in Patients With CF-LVAD [Phase 1, Phase 2]
Phase 1/2 trial evaluating omega-3 fatty acid therapy to prevent GI bleeding in patients with continuous-flow left ventricular assist device…
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CLINICAL_TRIALS trial_result · 2021-07-08Clinical Trial Update: Global rEgistry on decongestioN Therapy Using Less invasivE UltraFiltration
Clinical trial registry update for an invasive ultrafiltration therapy in acute heart failure and cardiac decompensation has terminated; res…
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CLINICAL_TRIALS trial_result · 2021-07-07Clinical Trial Update: Acupuncture for the Treatment of Medication-Dependent Hypotension in Heart Failure [Phase 1, Phase 2]
A clinical trial update on acupuncture as treatment for medication-dependent hypotension in heart failure, currently in Phase 1/Phase 2 with…
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CLINICAL_TRIALS trial_result · 2021-06-30Clinical Trial Update: SGLT2 Inhibition in Combination With Diuretics in Heart Failure [Phase 4]
Phase 4 trial updating on SGLT2 inhibitors in combination with diuretics for heart failure and type 2 diabetes mellitus; results have been p…
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CLINICAL_TRIALS trial_result · 2021-06-28Clinical Trial Update: Sensor-controlled Digital Game for Heart Failure Self-management [NA]
Clinical trial on a sensor-controlled digital game for self-management in heart failure has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-28Clinical Trial Update: Drug Use Investigation of Selara Tablets (an Investigation for Chronic Heart Failure)
Clinical trial update for Selara Tablets investigating use in chronic heart failure; study completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-06-25Clinical Trial Update: Treatment of Heart Failure Using Human Umbilical Cord Mesenchymal Stem Cells(hUC-MSC) [Phase 1, Phase 2]
Clinical trial update on treating heart failure with human umbilical cord mesenchymal stem cells (hUC-MSC) across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2021-06-18Clinical Trial Update: A Study That Looks at the Function of the Heart in Patients With Heart Failure Who Take Empagliflozin [Phase 3]
Phase 3 trial update evaluating the effect of empagliflozin on heart function in patients with heart failure has completed.