Heart Failure
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Trans-resveratrol's Influence on the Development of CHF in Early Postmenopausal Women with HTN and Reduced BMD [NA]
Clinical trial update on whether trans-resveratrol influences the development of congestive heart failure in early postmenopausal women with…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF
The Cleveland Clinic is sponsoring a clinical trial assessing guideline-directed management for heart failure, including participants affect…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: The Effect of Education Given to Patients With Heart Failure on Self-care, Drug Compliance and Quality of Life. [NA]
An update on a clinical trial evaluating education for patients with heart failure and its potential impact on self-care, medication adheren…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure [Phase 1]
Phase 1 trial evaluating the safety of mRNA-0184 in participants with heart failure has completed.
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CLINICAL_TRIALS research · 2025-03-17Clinical Trial Update: Wearable Assessment of Thoracic, Cardiac Health and Exercise Performance Trial
A clinical trial update from The University of Hong Kong for a wearable-based assessment of thoracic and cardiac health and exercise perform…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: IPSC-CMs Combined with LVAD or CABG for the Treatment of Heart Failure [Phase 1, Phase 2]
A Phase 1/2 clinical trial update evaluating the combination of induced pluripotent stem cell–derived cardiomyocytes (IPSC-CMs) with LVAD or…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Akershus Cardiac Examination 4 Study [NA]
An update on the Akershus Cardiac Examination 4 study, which is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Identifying Targets of Maladaptive Metabolic Responses in Heart Failure [NA]
A clinical trial update from AdventHealth Translational Research Institute describes a study aiming to identify targets of maladaptive metab…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: COVID-19, Patients' Evolution and the Influence of the Pandemic on Health Care and Outcomes in Chronic Diseases
Clinical trial NCT05168722 provides an update on how the COVID-19 pandemic affected health care delivery and patient outcomes in individuals…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Cardiac Structure and Function in Patients with Cystic Fibrosis
This document reports on a clinical trial evaluating cardiac structure and function in people with cystic fibrosis, including those with CF-…
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: A Randomized Controlled Trial of LOT-CRT Versus conventionaL BiVP in Heart Failure Patients With NICD [NA]
A randomized trial comparing LOT-CRT with conventional bi-ventricular pacing in heart failure patients with intraventricular conduction abno…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Efficacy of a Streamlined Heart Failure Optimization Protocol [NA]
The completed trial assesses the efficacy of a streamlined heart failure optimization protocol in patients with heart failure with reduced e…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: CSP Versus BiVP for Heart Failure Patients with RVP Upgraded to Cardiac Resynchronization Therapy [NA]
An ongoing clinical trial is evaluating Conduction System Pacing versus BiV pacing in heart failure patients upgraded to cardiac resynchroni…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients with Heart Failure (CONFIRMATION-HF) [Phase 3]
A Phase 3 randomized trial (CONFIRMATION-HF) is evaluating the efficacy and safety of combining finerenone with a SGLT2 inhibitor in hospita…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients with Heart Failure Who Are Intolerant or Not Eligible for Treatment with Steroidal Mineralocorticoid Receptor Antagonists [Phase 3]
Phase 3 clinical trial to evaluate the efficacy and safety of finerenone in heart failure patients who are intolerant or ineligible for ster…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB [NA]
A clinical trial is evaluating left bundle branch pacing as initial therapy for patients with non-ischemic heart failure and left bundle-bra…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
EMPOWER-1 is a multi-site cohort study sponsored by Future Genetics Limited aimed at reducing health inequality, focusing on cardiovascular …
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Assessment of the Effectiveness, Socio-economic Impact and Implementation of a Digital Solution for Severe Patients [NA]
A completed clinical trial evaluating the effectiveness, socio-economic impact, and implementation of a digital solution for patients with s…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Non-invasive Detection of Driveline Infections in Patients with a Left Ventricular Assist Device
A clinical trial is evaluating non-invasive methods to detect driveline infections in patients with an LVAD; the study is currently enrollin…
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: Dapagliflozin Effects on Cardiometabolic Outcomes in Patients With an Acute Heart Attack. [Phase 3]
Phase 3 trial update evaluates dapagliflozin for cardiometabolic outcomes in patients after an acute myocardial infarction. The study includ…
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FDA approval · 2025-03-07FDA Approved: BISOPROLOL FUMARATE — Supplemental Application (TruPharma LLC)
FDA approved a supplemental application for Bisoprolol Fumarate from TruPharma LLC, validating the generic product under ANDA075643.
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CLINICAL_TRIALS trial_result · 2025-03-07Clinical Trial Update: ORal IrON Supplementation with Ferric Maltol in Treating Iron Deficiency and Anaemia in Patients with Heart Failure (ORION-HF) [Phase 4]
Phase 4 clinical trial ORION-HF evaluating oral ferric maltol for iron deficiency anemia in patients with heart failure has completed.
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Investigating the Impact of Nudging Cardiologists to Prescribe Guideline-directed Medical Therapy in Heart Failure Patients [NA]
A clinical trial assessing whether nudging cardiologists to prescribe guideline-directed medical therapy affects prescribing practices in he…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Safety and Performance Evaluation of a New Catheter Range for Lead Implantation At Interventricular Septum [NA]
This entry reports on a clinical trial evaluating the safety and performance of a new catheter range for lead implantation at the interventr…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: Effect of Reduced Vasopressors on Mortality in ECMO-supported Cardiogenic Shock Patients
A ClinicalTrials.gov entry notes that a study evaluating whether reducing vasopressor use improves mortality in ECMO-supported cardiogenic s…