Heart Failure

• CLINICAL_TRIALS research · 2025-11-28
  Clinical Trial Update: Evaluation of Cardiac and Endothelial Function in Children and Adolescents Treated With Anthracycline

  This clinical trial update describes a study evaluating cardiac and endothelial function in children and adolescents treated with anthracycl…

• CLINICAL_TRIALS trial_result · 2025-11-26
  Clinical Trial Update: Guideline-Directed Medical Therapy in Patients After Implantation of Implantable Cardioverter Defibrillators to Improve Long-Term Outcomes [NA]

  This clinical trial update notes that a study evaluating guideline-directed medical therapy after implantable cardioverter defibrillator imp…

• CLINICAL_TRIALS research · 2025-11-26
  Clinical Trial Update: Sequential Cystatin C Levels and Renal Impairment in Acute Heart Failure

  This Cleveland Clinic-sponsored study evaluated sequential cystatin C levels to characterize renal impairment in patients with acute heart f…

• CLINICAL_TRIALS research · 2025-11-26
  Clinical Trial Update: The HIMALAYAS Trial and Lifestyle Changes in Pediatric, Adolescent and Young Adult Cancer Survivors Study: A Multicentre Randomized Controlled Trial [NA]

  This entry reports on the HIMALAYAS trial, a multicentre randomized controlled study investigating lifestyle changes in pediatric, adolescen…

• CLINICAL_TRIALS research · 2025-11-26
  Clinical Trial Update: The Role of 4 Different Consent Approaches on a Pilot Study to Increase Cardiac Rehabilitation Attendance [NA]

  This clinical trial update discusses a pilot study evaluating four different consent approaches to increase attendance at cardiac rehabilita…

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• CLINICAL_TRIALS research · 2025-11-25
  Clinical Trial Update: Efficacy and Safety Trials of Yangxinshi Tablets in the Treatment of Patients With Coronary Heart Disease Complicated by Cardiac Dysfunction [Phase 4]

  Phase 4 trials are ongoing to evaluate the efficacy and safety of Yangxinshi Tablets in patients with coronary heart disease complicated by …

• CLINICAL_TRIALS research · 2025-11-25
  Clinical Trial Update: A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure [NA]

  A recruiting clinical trial at Tufts Medical Center is evaluating a skeletal muscle recovery intervention using dietary protein for individu…

• CLINICAL_TRIALS trial_result · 2025-11-24
  Clinical Trial Update: Heart Failure Resilience Intervention for Caregivers [NA]

  A completed clinical trial evaluated a resilience intervention for caregivers of heart failure patients. Results were posted in 2025.

• CLINICAL_TRIALS research · 2025-11-24
  Clinical Trial Update: A Pilot Randomized Controlled Trial Comparing Core Exercise, Aerobic Exercise, and Combined Exercise in Patients Undergoing Phase II Cardiac Rehabilitation. [NA]

  A pilot randomized controlled trial compares core exercise, aerobic exercise, and combined exercise regimens in patients undergoing Phase II…

• CLINICAL_TRIALS research · 2025-11-24
  Clinical Trial Update: HF Prevalence and Evolution of HF in DM II Patients at High Risk

  AstraZeneca-sponsored registry study assessing the prevalence and progression of heart failure in high-risk patients with type 2 diabetes me…

• CLINICAL_TRIALS trial_result · 2025-11-24
  Clinical Trial Update: Values-Affirmation + Education Intervention Targeting Medication Adherence in Older Adults With Heart Failure [NA]

  This clinical trial update reports results for a values-affirmation plus education intervention aimed at improving medication adherence in o…

• CLINICAL_TRIALS research · 2025-11-24
  Clinical Trial Update: Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients [Phase 2]

  This update describes a Phase 2 clinical trial evaluating dapagliflozin for primary prevention of cardiotoxicity from anthracycline chemothe…

• CLINICAL_TRIALS research · 2025-11-24
  Clinical Trial Update: Real-world Dapagliflozin Experience in Patients With Heart Failure in Greece

  Real-world observational update on the use of dapagliflozin in patients with heart failure in Greece. The study has completed.

• CLINICAL_TRIALS research · 2025-11-24
  Clinical Trial Update: Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure [Phase 4]

  This Phase 4 clinical trial (Gator SCALES-WHF) is evaluating subcutaneous Lasix (furosemide) to relieve symptoms of worsening heart failure …

• CLINICAL_TRIALS trial_result · 2025-11-24
  Clinical Trial Update: Cardiac Rehabilitation in Heart Failure and Sarcopenia [NA]

  A clinical trial evaluating a cardiac rehabilitation program for heart failure has completed. The update references sarcopenia in the trial …

• CLINICAL_TRIALS trial_result · 2025-11-24
  Clinical Trial Update: Near Infrared Spectroscopy (NIRS) for Heart Failure Assessment. [NA]

  A clinical trial evaluating near-infrared spectroscopy for heart failure assessment, sponsored by Phoenix Children's Hospital, has been term…

• CLINICAL_TRIALS research · 2025-11-21
  Clinical Trial Update: Use of Bedside Imaging and Community Health Workers for Early Screening and Referral of Pre-symptomatic Stage B Heart Failure in the Emergency Department [NA]

  A clinical trial evaluating the use of bedside imaging and community health workers to screen for pre-symptomatic Stage B heart failure in t…

• CLINICAL_TRIALS research · 2025-11-20
  Clinical Trial Update: Treating Breast Cancer Patients Undergoing Trastuzumab Treatment With Carvedilol to Reduce Incidence of Heart Failure [Phase 2]

  A Phase 2 trial is investigating whether adding carvedilol to trastuzumab in breast cancer patients can lower the risk of developing heart f…

• CLINICAL_TRIALS trial_result · 2025-11-20
  Clinical Trial Update: Nebivolol for the Prevention of Left Ventricular Systolic Dysfunction in Patients With Duchenne Muscular Dystrophy [Phase 3]

  Phase 3 clinical trial evaluating nebivolol for prevention of left ventricular systolic dysfunction in Duchenne muscular dystrophy has compl…

• CLINICAL_TRIALS trial_result · 2025-11-20
  Clinical Trial Update: Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE) [NA]

  Completed clinical study evaluating a mobile case management approach to improve cardiac rehabilitation outcomes. The trial targeted patient…

• CLINICAL_TRIALS trial_result · 2025-11-20
  Clinical Trial Update: Post Approval Study (PAS) of the OPTIMIZER Smart and CCM Therapy

  Post-approval study (PAS) update for the OPTIMIZER Smart device and CCM therapy in heart failure; the study is currently active but not recr…

• CLINICAL_TRIALS trial_result · 2025-11-20
  Clinical Trial Update: Seerlinq: Non-invasive LVFP Monitoring in HF

  This clinical trial update reports on Seerlinq's non-invasive LVFP monitoring for heart failure. The study status is completed.

• CLINICAL_TRIALS research · 2025-11-20
  Clinical Trial Update: ASV Effects on Myocardial Energetics and Sympathetic Nerve Function in Heart Failure and Sleep Apnea. [NA]

  Clinical trial investigating the effects of Adaptive Servo-Ventilation (ASV) on myocardial energetics and sympathetic nerve function in hear…

• CLINICAL_TRIALS trial_result · 2025-11-19
  Clinical Trial Update: Efficacy and Safety of Sacubitril/Valsartan Compared With Enalapril on Morbidity, Mortality, and NT-proBNP Change in Patients With CCC [Phase 4]

  Phase 4 trial comparing sacubitril/valsartan to enalapril in patients with Chagas disease-related cardiomyopathy, assessing morbidity, morta…

• CLINICAL_TRIALS research · 2025-11-19
  Clinical Trial Update: Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure

  A clinical trial update on the real-world effectiveness of the Cordella Pulmonary Artery Sensor System in patients with heart failure, curre…