Heart Failure
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Contrast-Induced Acute Kidney Injury Prevention in Acute Heart Failure [NA]
This clinical trial is currently recruiting to evaluate prevention of contrast-induced acute kidney injury in patients with acute heart fail…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: DuoCor 2 DOMINATE Study [NA]
A status update on the DuoCor 2 DOMINATE Study for advanced heart failure indicates the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Impact of Peripheral Vascular Stiffness Assessment on Risk Prediction in Patients With Myocardial Infarction
A ClinicalTrials.gov update describes a study on whether peripheral vascular stiffness assessment improves risk prediction in patients with …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Phase I Study of HRS-5765 in Healthy Participants [Phase 1]
A Phase 1 study of HRS-5765 in healthy participants is planned, with Heart Failure listed as the condition; the trial is not yet recruiting.
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CLINICAL_TRIALS other · 2026-04-24Clinical Trial Update: Peripheral Venous Pressure (PVP) Trial [NA]
Clinical trial update for the Peripheral Venous Pressure (PVP) trial in congestive heart failure states the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)
MAP-HEART is an ongoing clinical trial in heart failure, currently enrolling by invitation to study multi-scale phenotypes.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery [NA]
This clinical trial update notes initiation and titration of guideline-directed medical therapy in patients with heart failure and cardiogen…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study of LY3971297 in Participants With Heart Failure [Phase 1]
Phase 1 study of LY3971297 in participants with heart failure (including diastolic and systolic subtypes) is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure [NA]
Recruitment is underway for a Barostim-enabled neurohormonal intervention intended to improve treatment of heart failure. The conditions inc…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: CCM OPEN HF Registry
This entry updates the CCM OPEN HF Registry clinical trial, sponsored by Impulse Dynamics, and indicates the study is currently recruiting p…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Bachmann Bundle Pacing for Prevention of New-Onset Atrial Fibrillation in Patients With Heart Failure [NA]
A clinical trial update for Bachmann Bundle pacing aimed at preventing new-onset atrial fibrillation in patients with heart failure; the stu…
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EMA approval · 2026-04-22EMA Authorised: Forxiga (dapagliflozin propanediol monohydrate) — AstraZeneca AB
EMA authorised Forxiga (dapagliflozin propanediol monohydrate) for type 2 diabetes mellitus, heart failure (systolic), and chronic kidney di…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Real-World Experience - Barostim™ Advancing the Level of Clinical Evidence (REBALANCE Registry)
A real-world evidence update from the REBALANCE Registry evaluating Barostim for heart failure; the registry is active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Optimized Treatment of Pulmonary Edema or Congestion [Phase 4]
Phase 4 clinical trial update on optimized treatment of pulmonary edema or congestion. Recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Selenium Intervention Registry Randomized Trial in Heart Failure [Phase 3]
A Phase 3 randomized trial evaluating selenium supplementation in patients with various forms of heart failure is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: HeartLogic™ in Patients With Heart Failure. [NA]
Clinical trial update on HeartLogic in patients with heart failure; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
Clinical trial update for an adult heart transplant immunosuppression study guided by microRNA levels; the study is currently recruiting.
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EMA approval · 2026-04-21EMA Authorised: Verquvo (vericiguat) — Bayer AG
EMA authorised Verquvo (vericiguat) from Bayer AG for the treatment of heart failure. This marks EU marketing authorisation for the medicine…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: ARNI Combined With SGLT2 Inhibitors on Functional Mitral Regurgitation Remodeling
A completed clinical trial (NCT07379788) is evaluating the combination of an ARNI (sacubitril/valsartan) with SGLT2 inhibitors for remodelin…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Sacubitril-valsartan in Patients With Heart Failure. [NA]
This clinical trial update reports on sacubitril-valsartan in patients with heart failure. The study is listed as completed.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Large Language Model-Generated Messages to Improve Guideline-Directed Medical Therapy in Heart Failure [NA]
A clinical trial protocol investigating the use of large language model-generated messages to improve adherence to guideline-directed medica…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Alleviant ALLAY-HFrEF Study [NA]
Alleviant Medical's ALLAY-HFrEF trial is currently enrolling by invitation for heart failure, with no results reported yet.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF) [Phase 2]
Pfizer is conducting a Phase 2 study called BRANCH-HF to evaluate PF-07328948 in adults with heart failure. The trial status is currently re…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Improving Self-Care of Caregivers of Adults in Homecare With Heart Failure and Cognitive Impairment [NA]
This clinical trial update describes a study evaluating an intervention to improve self-care for caregivers of adults with heart failure and…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Alleviant ALLAY-HF Study [NA]
The ALLAY-HF trial for heart failure is currently enrolling by invitation, sponsored by Alleviant Medical, Inc. The listing does not specify…