Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2008-05-01FDA Approved: HYDROCHLOROTHIAZIDE — Supplemental Application (Leading Pharma, LLC)
The FDA approved a supplemental application for hydrochlorothiazide submitted by Leading Pharma, LLC. This action updates the drug's labelin…
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FDA approval · 2008-04-30FDA Approved: BUMETANIDE — Original Application (Civica, Inc.)
FDA approved Civica, Inc.'s original application for bumetanide, authorizing a generic version of the diuretic bumetanide.
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FDA approval · 2008-04-23FDA Approved: ENALAPRIL MALEATE — Supplemental Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
The FDA approved a supplemental application for enalapril maleate (a generic ACE inhibitor) by Heritage Pharmaceuticals (d/b/a Avet Pharmace…
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CLINICAL_TRIALS trial_result · 2008-04-22Clinical Trial Update: Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF) [Phase 4]
A Phase 4 clinical trial evaluating the effect of spironolactone on insulin resistance in patients with chronic heart failure has completed.
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CLINICAL_TRIALS trial_result · 2008-04-22Clinical Trial Update: Flu Vaccination in Congestive Heart Failure [Phase 4]
Phase 4 trial evaluating influenza vaccination in patients with heart failure has completed.
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CLINICAL_TRIALS trial_result · 2008-04-22Clinical Trial Update: Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure [Phase 4]
A Phase 4 clinical trial assessing the effects of spironolactone on matrix metalloproteinases in heart failure has completed. The study was …
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CLINICAL_TRIALS trial_result · 2008-04-22Clinical Trial Update: Study to Evaluate the Effect of SLV320 in Addition to Chronic Furosemide Treatment on Renal Function in Subjects With Congestive Heart Failure and Impaired Renal Function
A clinical trial evaluating SLV320 added to chronic furosemide treatment in subjects with congestive heart failure and impaired renal functi…
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CLINICAL_TRIALS trial_result · 2008-04-22Clinical Trial Update: Effects of Losartan on Insulin Resistance in Patients With Heart Failure [Phase 4]
Phase 4 trial evaluating losartan for insulin resistance in heart failure patients has completed.
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CLINICAL_TRIALS trial_result · 2008-04-14Clinical Trial Update: Clinical Evaluation on Advanced Resynchronization [Phase 4]
Phase 4 clinical evaluation of advanced resynchronization therapy conducted by LivaNova has completed.
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FDA approval · 2008-04-10FDA Approved: TORSEMIDE — Supplemental Application (Chartwell RX, LLC)
FDA approved Chartwell RX, LLC's supplemental application for Torsemide, enabling the requested changes to the product's approval.
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CLINICAL_TRIALS trial_result · 2008-04-09Clinical Trial Update: Enteral Nutrition in Congestive Heart Failure and Cardiac Cachexia [Phase 2]
A Phase 2 clinical trial investigating enteral nutrition in chronic heart failure with cardiac cachexia has completed.
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CLINICAL_TRIALS trial_result · 2008-04-04Clinical Trial Update: Effects of MK7418 on Diuresis and Renal Function in Congestive Heart Failure Patients [Phase 2]
Phase 2 clinical trial evaluating MK7418 for diuresis and renal function in patients with congestive heart failure has completed.
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CLINICAL_TRIALS research · 2008-03-28Clinical Trial Update: Echo Assessment of Intraventricular Dyssynchrony
A clinical trial update on echocardiographic assessment of intraventricular dyssynchrony in patients with chronic heart failure, ischemic he…
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CLINICAL_TRIALS trial_result · 2008-03-13Clinical Trial Update: The Effects of the Inspiratory Muscle Plus Aerobic Training Compare to Aerobic Training Alone in Heart Failure Patients. [NA]
A clinical trial compares inspiratory muscle training plus aerobic exercise to aerobic exercise alone in patients with heart failure; the cu…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: The Role of Angiotensin Type I Receptor in the Regulation of Human Peripheral Vascular Function [Phase 3]
This is a completed Phase 3 trial assessing the role of the angiotensin type I receptor in regulating human peripheral vascular function.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular Function [Phase 3]
A Phase 3 trial explored the role of the Angiotensin Type I receptor in regulating human coronary vascular function and has completed.
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: PET Scan to Determine Areas of Blood Flow and Activity in the Hearts of Patients With Heart Disease Taking Beta-Blockers [Phase 2]
Completed Phase 2 study using PET imaging to map areas of blood flow and activity in the hearts of patients with heart failure who are takin…
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CLINICAL_TRIALS trial_result · 2008-02-29Clinical Trial Update: SAVEPACe - Search AV Extension and Managed Ventricular Pacing for Promoting Atrio-Ventricular Conduction [NA]
Update on the SAVEPACe trial evaluating AV extension and managed ventricular pacing to promote atrioventricular conduction; the study status…
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FDA approval · 2008-02-27FDA Approved: MILRINONE LACTATE IN DEXTROSE — Supplemental Application (Baxter Healthcare Corporation)
FDA approved Baxter's supplemental application for milrinone lactate in dextrose under the ANDA pathway.
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CLINICAL_TRIALS trial_result · 2008-02-26Clinical Trial Update: Hospitalization at Home of Elderly Patients With Heart Failure [NA]
This update reports the completion of a clinical trial evaluating hospitalization at home for elderly patients with heart failure. The study…
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CLINICAL_TRIALS trial_result · 2008-02-22Clinical Trial Update: Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure [Phase 4]
A Phase 4 clinical trial evaluated the effect of preoperative furosemide on intraoperative blood pressure; the study is completed.
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FDA approval · 2008-02-15FDA Approved: TOPROL XL — Supplemental Application (Melinta Therapeutics, LLC)
FDA approved a supplemental NDA for TOPROL XL (metoprolol succinate) from Melinta Therapeutics, LLC, providing an additional or revised appr…
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CLINICAL_TRIALS research · 2008-02-15Clinical Trial Update: A Phase II Trial to Assess Hemodynamic Effects of Istaroxime in Pts With Worsening HF and Reduced LV Systolic Function [Phase 2]
A Phase II trial assessing the hemodynamic effects of istaroxime in patients with worsening heart failure and reduced left ventricular systo…
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FDA approval · 2008-02-15FDA Approved: QUINAPRIL — Supplemental Application (BluePoint Laboratories)
FDA approved a supplemental application for Quinapril submitted by BluePoint Laboratories.
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CLINICAL_TRIALS trial_result · 2008-02-13Clinical Trial Update: D2-EPG Study: Evaluation of New Sensing Circuitry and Capture Management [NA]
The D2-EPG study evaluating new sensing circuitry and capture management for a Medtronic cardiac device has completed.