Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2009-05-07Clinical Trial Update: RESTOR-MV: Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve [Phase 2]
A Phase 2 randomized trial evaluating an off-pump mitral valve repair approach (RESTOR-MV) for mitral regurgitation in patients with left ve…
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FDA approval · 2009-05-04FDA Approved: FUROSEMIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for furosemide from Hikma Pharmaceuticals USA Inc., updating the labeling on an existing product.
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FDA approval · 2009-05-04FDA Approved: FUROSEMIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for furosemide submitted by Hikma Pharmaceuticals USA Inc.
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FDA approval · 2009-05-04FDA Approved: FUROSEMIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for furosemide submitted by Hikma Pharmaceuticals USA Inc.
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CLINICAL_TRIALS trial_result · 2009-05-01Clinical Trial Update: Evaluation of the Effect of AVE0657 in Cheynes-Stokes Breathing Syndrome Patients [Phase 2]
A Phase 2 clinical trial evaluating AVE0657 for Cheyne-Stokes respiration in patients with heart failure and sleep apnea was terminated.
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FDA approval · 2009-04-30FDA Approved: SPIRONOLACTONE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved Sun Pharmaceutical Industries, Inc.'s supplemental ANDA for spironolactone, granting approval of their generic product for the …
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CLINICAL_TRIALS trial_result · 2009-04-23Clinical Trial Update: Prospective Registry of Pacemaker Patients Concerning Percentage of Right Ventricular Pacing, LVEF and NYHA Class
This completed prospective registry update analyzes right ventricular pacing percentage in pacemaker patients and its relationship to left v…
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CLINICAL_TRIALS research · 2009-04-22Clinical Trial Update: Ability of Metoprolol to Alter the Exercise Induced Elevation of Catecholamines [Phase 4]
This Phase 4 clinical trial investigates whether metoprolol can modify the exercise-induced rise in catecholamines in patients with heart fa…
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CLINICAL_TRIALS trial_result · 2009-04-15Clinical Trial Update: A Pilot Study of Recombinant Human Relaxin (rhRlx) in Compensated Congestive Heart Failure [Phase 2]
This document reports the completion of a Phase 2 pilot trial evaluating recombinant human relaxin in patients with compensated congestive h…
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CLINICAL_TRIALS trial_result · 2009-04-09Clinical Trial Update: Dyspnea and Biomarkers in a Prehospital Setting
A prehospital trial examining dyspnea and related biomarkers has completed, evaluating patients with dyspnea and conditions such as heart fa…
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CLINICAL_TRIALS research · 2009-04-08Clinical Trial Update: Prednisone for Decompensated Congestive Heart Failure [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating prednisone for decompensated congestive heart failure has been suspended.
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CLINICAL_TRIALS research · 2009-04-02Clinical Trial Update: Evolution of Management Strategies of Heart Failure Patients With Implantable Defibrillators
This is a clinical trial update examining evolving management strategies for heart failure patients with implantable defibrillators, sponsor…
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CLINICAL_TRIALS research · 2009-03-30Clinical Trial Update: Study of Anginera in Adults With a Left Ventricular Assist Device (LVAD) as Bridge to Transplant [Phase 1]
This is a Phase 1 clinical trial evaluating Anginera in adults with heart failure who have a left ventricular assist device (LVAD) as a brid…
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CLINICAL_TRIALS trial_result · 2009-03-26Clinical Trial Update: Metabolic Derangements in Acute Heart Failure Syndrome
A Cleveland Clinic-sponsored clinical trial on metabolic derangements in acute heart failure syndrome has been terminated. The study involve…
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CLINICAL_TRIALS trial_result · 2009-03-25Clinical Trial Update: Safety Study of CD-NP in Heart Failure [Phase 1]
Phase 1 safety evaluation of CD-NP in congestive heart failure has completed.
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CLINICAL_TRIALS trial_result · 2009-03-13Clinical Trial Update: A Study to Compare the Effects of Coreg CR and Coreg IR on Heart Function in Subjects With Stable Chronic Heart Failure [Phase 3]
Phase 3 trial comparing Coreg CR and Coreg IR in stable chronic heart failure has completed with results posted in 2009.
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FDA approval · 2009-03-12FDA Approved: FUROSEMIDE — Supplemental Application (Chartwell RX, LLC)
FDA approved a supplemental application for furosemide submitted by Chartwell RX, LLC, resulting in updated labeling for the product.
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CLINICAL_TRIALS trial_result · 2009-03-06Clinical Trial Update: Functional Circuit Training in Older Adults With Congestive Heart Failure [NA]
This entry notes the completion of a clinical trial evaluating functional circuit training in older adults with congestive heart failure.
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FDA approval · 2009-02-25FDA Approved: SPIRONOLACTONE — Supplemental Application (Mylan Pharmaceuticals Inc.)
The FDA approved a supplemental application for Spironolactone submitted by Mylan Pharmaceuticals Inc.
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CLINICAL_TRIALS trial_result · 2009-02-24Clinical Trial Update: Evaluating Effects of a Left Bundle Branch Block
The document notes a completed clinical trial evaluating the effects of left bundle branch block on mechanical dyssynchrony and heart failur…
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FDA approval · 2009-02-20FDA Approved: FUROSEMIDE — Supplemental Application (Solco Healthcare LLC)
The FDA approved a supplemental application for furosemide from Solco Healthcare LLC, adding a new manufacturing source for the product.
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CLINICAL_TRIALS trial_result · 2009-02-20Clinical Trial Update: Placebo-Controlled Randomized Study of KW-3902 for Subjects Hospitalized With Worsening Renal Function and Heart Failure Requiring IV Therapy [Phase 3]
Phase 3 placebo-controlled randomized study of KW-3902 in hospitalized patients with worsening renal function and heart failure requiring IV…
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CLINICAL_TRIALS trial_result · 2009-02-20Clinical Trial Update: Nicorandil Study to Reduce Cardiac Death After Percutaneous Coronary Intervention (PCI) in Hemodialysis Patients [NA]
A completed clinical trial assessing nicorandil to reduce cardiac death after PCI in hemodialysis patients, sponsored by Toujinkai Hospital.
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CLINICAL_TRIALS trial_result · 2009-02-20Clinical Trial Update: ELECTION - The Electrode Configuration Cardiac Resynchronization Therapy (CRT) Study (ELECTION)
The ELECTION trial, evaluating electrode configuration for cardiac resynchronization therapy, has completed, reporting results from Guidant'…
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CLINICAL_TRIALS trial_result · 2009-02-19Clinical Trial Update: Glucose Control in Open Heart Surgery [Phase 1]
A Phase 1 trial evaluating glucose control during open heart surgery has completed.