Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2010-01-28FDA Approved: ENALAPRIL MALEATE — Supplemental Application (Taro Pharmaceuticals U.S.A., Inc.)
FDA approved a supplemental application for enalapril maleate from Taro Pharmaceuticals U.S.A., Inc., authorizing the generic product under …
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CLINICAL_TRIALS research · 2010-01-25Clinical Trial Update: Developing a New, Dynamic, Therapeutic Pacemaker Algorithm for Stabilising Periodic Breathing in Chronic Heart Failure. [Phase 2]
A Phase 2 clinical trial is evaluating a dynamic pacemaker algorithm to stabilize periodic breathing in chronic heart failure; the current s…
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FDA approval · 2010-01-21FDA Approved: BUMEX — Supplemental Application (Validus Pharmaceuticals LLC)
FDA approved a supplemental application for Bumex (bumetanide) submitted by Validus Pharmaceuticals LLC.
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FDA approval · 2010-01-21FDA Approved: MILRINONE LACTATE IN DEXTROSE — Original Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved Hikma Pharmaceuticals USA Inc.'s Milrinone Lactate in Dextrose as an Original Application (ANDA 090038), establishing a gen…
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CLINICAL_TRIALS trial_result · 2010-01-21Clinical Trial Update: Coventry Outcomes Study of Seniors (COSS): A Comparative Effectiveness Study to Evaluate the Effect of a Multidisciplinary Team's Intervention on the Incidence of Nonelective Hospitalizations in a Medicare Population [NA]
The Coventry Outcomes Study of Seniors (COSS), a comparative effectiveness trial assessing a multidisciplinary team's intervention to reduce…
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CLINICAL_TRIALS research · 2010-01-20Clinical Trial Update: Add-on Aliskiren Treatment in Patients With Chronic Congestive Heart Failure [Phase 4]
A Phase 4 clinical trial is evaluating add-on aliskiren for patients with chronic heart failure; the current trial status is unknown.
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FDA approval · 2010-01-19FDA Approved: TOPROL XL — Supplemental Application (Melinta Therapeutics, LLC)
FDA approved a supplemental application for TOPROL XL (metoprolol succinate) submitted by Melinta Therapeutics, LLC.
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CLINICAL_TRIALS trial_result · 2010-01-18Clinical Trial Update: Interventricular Delay of Lumax HF-T for Heart Failure [Phase 2]
Phase 2 clinical trial results update on Lumax HF-T device evaluating interventricular delay in patients with heart failure; results posted …
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CLINICAL_TRIALS trial_result · 2010-01-18Clinical Trial Update: TRIAGE-CRT Telemonitoring in Patients With CHF and Indication of CRT-D [Phase 4]
A Phase 4 telemonitoring trial (TRIAGE-CRT) in patients with heart failure and a CRT-D device has completed, with results posted in January …
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CLINICAL_TRIALS research · 2010-01-14Clinical Trial Update: The Cyclocapnic Method for Measurement of Chemosensitivity [Phase 1]
This update describes a Phase 1 trial evaluating the cyclocapnic method for measuring chemosensitivity, in conditions including periodic bre…
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CLINICAL_TRIALS trial_result · 2010-01-13Clinical Trial Update: The BENEFICIAL Study: Evaluating the Efficacy and Safety of Alagebrium (ALT-711) in Patients With Chronic Heart Failure [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of Alagebrium (ALT-711) in patients with chronic heart failure has completed.
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CLINICAL_TRIALS research · 2010-01-13Clinical Trial Update: Breathing Disorders in Patients With Congestive Heart Failure
This clinical trial update reports a completed study investigating breathing disorders in patients with congestive heart failure. The study …
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CLINICAL_TRIALS trial_result · 2010-01-06Clinical Trial Update: A Family Intervention for Improving Self-Care of Patients With Heart Failure [EARLY_Phase 1]
This document reports the completion status of a Phase 1 clinical trial evaluating a family-based intervention to improve self-care in patie…
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CLINICAL_TRIALS other · 2009-12-25Clinical Trial Update: Randomized Trial for Patients With Chronic Heart Failure With Acute Decompensation [NA]
A randomized trial in patients with chronic heart failure with acute decompensation has been terminated. The update notes the termination st…
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CLINICAL_TRIALS research · 2009-12-23Clinical Trial Update: Exercise in Patients With a Biventricular Pacemaker [Phase 2, Phase 3]
This clinical trial update describes a Phase 2/Phase 3 study investigating exercise in patients with a biventricular pacemaker and heart fai…
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FDA approval · 2009-12-22FDA Approved: CARVEDILOL — Original Application (Advagen Pharma Limited)
FDA approves the original application for a generic carvedilol product by Advagen Pharma Limited.
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CLINICAL_TRIALS trial_result · 2009-12-18Clinical Trial Update: Response to Influenza Virus Vaccination in Patients Immunocompromised Due to Chemotherapy [NA]
This completed study evaluated the immune response to influenza vaccination in patients who are immunocompromised due to chemotherapy. The t…
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CLINICAL_TRIALS research · 2009-12-10Clinical Trial Update: CABG Combined Pedicled Omentum Wrapped Autologous Atrial Tissue Patch Cardiomyoplasty for Ischemic Cardiomyopathy [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial evaluating a surgical technique—CABG combined pedicled omentum-wrapped autologous atrial tissue patch cardiom…
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CLINICAL_TRIALS trial_result · 2009-12-01Clinical Trial Update: Study of the Effectiveness of Report Cards on the Quality of Care for Heart Attack and Heart Failure Patients [NA]
This completed clinical trial evaluated whether providing performance report cards improves the quality of care for patients with acute myoc…
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FDA approval · 2009-11-18FDA Approved: LISINOPRIL — Supplemental Application (Quallent Pharmaceuticals Health LLC)
FDA approved a supplemental application for lisinopril from Quallent Pharmaceuticals Health LLC, approving this generic lisinopril product.
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CLINICAL_TRIALS withdrawal · 2009-11-17Clinical Trial Update: Non-invasive Evaluation of Heart Transplant Rejection- Pilot Study
This pilot study evaluating non-invasive methods to assess heart transplant rejection was withdrawn prior to completion.
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CLINICAL_TRIALS trial_result · 2009-11-16Clinical Trial Update: Brain Natriuretic Peptide (BNP) to Preserve Renal Function in Hospitalized Patients With Heart Failure [Phase 3]
A Phase 3 clinical trial evaluating Brain Natriuretic Peptide (BNP) to preserve renal function in hospitalized patients with congestive hear…
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CLINICAL_TRIALS trial_result · 2009-11-11Clinical Trial Update: Evaluation of a Portable Device for Assessing Sleep Disordered Breathing in Congestive Heart Failure
A completed clinical trial evaluated a portable device for detecting sleep-disordered breathing in patients with congestive heart failure.
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CLINICAL_TRIALS trial_result · 2009-11-10Clinical Trial Update: Clinical Usefulness and Efficacy of Intrathoracic Impedance Monitoring Using the OptiVol Patient Alert(TM)
This completed trial assessed the usefulness and efficacy of intrathoracic impedance monitoring with the OptiVol Patient Alert for managing …
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CLINICAL_TRIALS research · 2009-11-06Clinical Trial Update: Correlation Of Respiratory Rate Level And Trend Evaluation in Heart Failure Patients
A terminated clinical trial sponsored by Boston Scientific investigated the relationship between respiratory rate level and trend in heart f…