Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2010-09-28FDA Approved: TORSEMIDE — Supplemental Application (Chartwell RX, LLC)
The FDA approved a supplemental application for torsemide submitted by Chartwell RX, LLC under ANDA 076894. The action approves changes to t…
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CLINICAL_TRIALS trial_result · 2010-09-28Clinical Trial Update: Galectin-3 Binding Protein in Cardiovascular Disease and Chronic Heart Failure
This entry reports the completion of a Heidelberg University–led clinical trial evaluating galectin-3 binding protein in heart failure and o…
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CLINICAL_TRIALS trial_result · 2010-09-28Clinical Trial Update: FAST (Fluid Accumulation Status Trial) [NA]
A completed clinical trial update for the FAST trial assessing fluid accumulation status in heart failure, with results posted.
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CLINICAL_TRIALS trial_result · 2010-09-24Clinical Trial Update: Changes of Left Ventricular Mass and Cardiac Function in Patients With Active Acromegaly During Treatment With the Growth Hormone Receptor Antagonist Pegvisomant [Phase 4]
This Phase 4 trial update investigates changes in left ventricular mass and cardiac function in patients with active acromegaly who are trea…
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CLINICAL_TRIALS trial_result · 2010-09-24Clinical Trial Update: Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction [Phase 1]
A Phase 1 study evaluating low-dose nesiritide with or without sildenafil in patients with heart failure and renal dysfunction was terminate…
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CLINICAL_TRIALS trial_result · 2010-09-23Clinical Trial Update: PEGASUS CRT Study: Atrial Support Study in Cardiac Resynchronization Therapy [Phase 4]
Phase 4 trial update for PEGASUS CRT Study evaluating atrial support in cardiac resynchronization therapy; completed with results posted in …
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FDA approval · 2010-09-17FDA Approved: QUINAPRIL — Supplemental Application (BluePoint Laboratories)
FDA approves a supplemental application for Quinapril from BluePoint Laboratories, a generic ACE inhibitor.
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CLINICAL_TRIALS trial_result · 2010-09-17Clinical Trial Update: The Effects of Nitric Oxide for Inhalation During Left Ventricular Assists Device (LVAD) Implantation [Phase 2]
A Phase 2 trial evaluating inhaled nitric oxide during left ventricular assist device implantation in congestive heart failure, with results…
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CLINICAL_TRIALS trial_result · 2010-09-16Clinical Trial Update: Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart Network [Phase 3]
Phase 3 trial evaluating ACE inhibitor therapy in infants with single-ventricle congenital heart disease has completed and results have been…
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CLINICAL_TRIALS trial_result · 2010-09-16Clinical Trial Update: Nebivolol Versus Bisoprolol Versus Carvedilol in Heart Failure [Phase 4]
This Phase 4 trial directly comparing nebivolol, bisoprolol, and carvedilol in chronic heart failure has completed.
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CLINICAL_TRIALS trial_result · 2010-09-14Clinical Trial Update: Evaluation of NT PRO BNP Guided Therapy on Hospitalization Rate and Mortality in Patients With Chronic HF NYHA II-IY
Completed clinical trial evaluating NT-proBNP-guided therapy for reducing hospitalization and mortality in chronic heart failure.
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CLINICAL_TRIALS withdrawal · 2010-09-14Clinical Trial Update: Stem Cell Study for Patients With Heart Failure [Phase 2]
A Phase 2 stem cell trial for heart failure/ischemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2010-09-09Clinical Trial Update: Depression and Quality of Life in Chronic Heart Failure Patients and the Caregivers [NA]
A completed clinical trial investigating depression and quality of life in chronic heart failure patients and their caregivers, focusing on …
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CLINICAL_TRIALS trial_result · 2010-09-08Clinical Trial Update: SYNCHRO. Evaluation of the Forecasts Parameters of Real Time-three-dimensional Doppler Echocardiography in Selecting Patients With Chronic Heart Failure for Cardiac Resynchronisation Therapy [NA]
The study completed evaluation of real-time three-dimensional Doppler echocardiography parameters for selecting chronic heart failure patien…
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CLINICAL_TRIALS trial_result · 2010-09-01Clinical Trial Update: Prednisone for Heart Failure Patients With Hyperuricemia [Phase 4]
A Phase 4 clinical trial evaluating prednisone in patients with heart failure and hyperuricemia has completed. The study was sponsored by He…
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CLINICAL_TRIALS trial_result · 2010-08-30Clinical Trial Update: Efficacy and Safety of Pulsed Infusions of Levosimendan in Outpatients With Advanced Heart Failure [Phase 3]
This clinical trial update reports Phase 3 data on pulsed infusions of levosimendan in outpatients with advanced heart failure, focusing on …
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CLINICAL_TRIALS trial_result · 2010-08-23Clinical Trial Update: Phase II Study of the Effect of CK-1827452 Injection on Myocardial Efficiency [Phase 2]
Phase II study of CK-1827452 in heart failure was terminated with results posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-08-20Clinical Trial Update: Optivol Diagnostic Data for Discharge in Heart Failure
A completed clinical trial assessing OptiVol diagnostic data to inform discharge decisions for patients with heart failure, sponsored by Tho…
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CLINICAL_TRIALS research · 2010-08-20Clinical Trial Update: Measuring G Protein-coupled Receptor Kinase-2 (GRK2) in the Blood to Diagnose and Treat Patients With Heart Failure
A completed clinical trial investigating whether measuring G protein-coupled receptor kinase-2 (GRK2) in blood can aid diagnosis and treatme…
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CLINICAL_TRIALS trial_result · 2010-08-19Clinical Trial Update: A Phase I/II Clinical Study of SK&F-105517-D in Japanese Patients With Chronic Heart Failure [Phase 1]
Phase I/II trial of SK&F-105517-D in Japanese patients with chronic heart failure has completed Phase 1, with results posted.
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CLINICAL_TRIALS trial_result · 2010-08-18Clinical Trial Update: CRT RENEWAL Registry
Boston Scientific's CRT RENEWAL Registry trial, which evaluates cardiac resynchronization therapy devices for heart failure, has completed.
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CLINICAL_TRIALS trial_result · 2010-08-16Clinical Trial Update: A Study of CK-1827452 Infusion in Stable Heart Failure [Phase 2]
Phase 2 trial update for CK-1827452 infusion in stable heart failure has completed with results posted.
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CLINICAL_TRIALS trial_result · 2010-08-10Clinical Trial Update: Investigating Systemic and Local Vascular Responses to Apelin in the Context of Renin-angiotensin Upregulation [NA]
A completed University of Edinburgh trial investigated how apelin modulates systemic and local vascular responses in the context of renin-an…
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CLINICAL_TRIALS trial_result · 2010-08-10Clinical Trial Update: Laboratory Outcome Predictors in Coronary Surgery
This clinical trial update notes completion of a study evaluating laboratory outcome predictors in patients undergoing coronary artery bypas…
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CLINICAL_TRIALS trial_result · 2010-08-02Clinical Trial Update: Study to Evaluate Potential Decrease in Hospitalization Events, Time Between Events, and Increasing Longevity in Patients With Symptomatic Heart Failure (0954-948) [Phase 3]
Phase 3 clinical trial update from Organon evaluating a heart failure therapy for reducing hospitalizations, increasing time between events,…