Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Added) [Phase 3]
This is a Phase 3 CHARM Added trial evaluating candesartan cilexetil in patients with heart failure already on ACE inhibitors; the study sta…
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FDA approval · 2011-01-25FDA Approved: COREG — Supplemental Application (Waylis Therapeutics LLC)
FDA approved a supplemental application for COREG (carvedilol) submitted by Waylis Therapeutics LLC. The action represents a label-related c…
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: Candesartan in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Alternative) [Phase 3]
A Phase 3 clinical trial update for CHARM Alternative evaluating candesartan in congestive heart failure; the study status is completed.
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: Candesartan Cilexetil in Heart Failure Assessment of Reduction in Mortality and Morbidity (CHARM Preserved) [Phase 3]
Phase 3 CHARM Preserved trial evaluating candesartan cilexetil in heart failure has completed.
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CLINICAL_TRIALS research · 2011-01-24Clinical Trial Update: Speckle Tracking Imaging and Realtime 3 Dimensional Echocardiograhy to Study LV Function and Remodeling After Acute Myocardial Infarction (AMI)
This clinical trial update describes the use of speckle-tracking imaging and real-time 3D echocardiography to study left ventricular functio…
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CLINICAL_TRIALS trial_result · 2011-01-21Clinical Trial Update: Mind-body Interventions in Cardiac Patients [NA]
This clinical trial update notes that a study of mind-body interventions in cardiac patients has completed. The study included participants …
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CLINICAL_TRIALS trial_result · 2011-01-21Clinical Trial Update: Study on Mechanical and Electrical Alternans
This clinical trial update reports on a study evaluating mechanical and electrical alternans in patients with heart failure and ischemia. Ve…
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FDA approval · 2011-01-12FDA Approved: RAMIPRIL — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for RAMIPRIL (ramipril) from Hikma Pharmaceuticals USA Inc., allowing a generic ramipril product to …
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CLINICAL_TRIALS trial_result · 2011-01-07Clinical Trial Update: Evaluation of Clinical Signs and Symptoms of Chronic Heart Failure in Patients Treated With Candesartan Cilexetil in Croatia
A completed clinical trial in Croatia evaluated the effects of candesartan cilexetil on clinical signs and symptoms in patients with chronic…
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FDA approval · 2011-01-06FDA Approved: COREG — Supplemental Application (Waylis Therapeutics LLC)
The FDA approved a supplemental application for COREG (carvedilol) submitted by Waylis Therapeutics LLC.
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FDA approval · 2011-01-06FDA Approved: COREG CR — Supplemental Application (Waylis Therapeutics LLC)
FDA approved a supplemental application for COREG CR (carvedilol phosphate) submitted by Waylis Therapeutics LLC.
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CLINICAL_TRIALS trial_result · 2010-12-30Clinical Trial Update: Therapeutic Thoracentesis for Patients With Congestive Heart Failure and Large Pleural Effusion [NA]
ClinicalTrials.gov entry indicates a completed study of therapeutic thoracentesis for patients with congestive heart failure and large pleur…
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CLINICAL_TRIALS trial_result · 2010-12-29Clinical Trial Update: Model 4296 Left Ventricular (LV) Lead Study [NA]
A completed clinical trial (NCT00927251) evaluating Medtronic's Model 4296 Left Ventricular Lead for heart failure; results were posted in 2…
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FDA approval · 2010-12-27FDA Approved: RAMIPRIL — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for ramipril from Hikma Pharmaceuticals USA Inc., likely related to labeling or formulation changes …
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FDA approval · 2010-12-27FDA Approved: FUROSEMIDE — Supplemental Application (Chartwell RX, LLC)
FDA approved a supplemental application for furosemide filed by Chartwell RX, LLC, authorizing changes under the supplemental NDA. The appro…
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CLINICAL_TRIALS trial_result · 2010-12-23Clinical Trial Update: Thiamine Supplementation in Heart Failure Patients Receiving Full Medical Therapy [Phase 3]
A Phase 3 clinical trial evaluating thiamine supplementation in chronic heart failure patients receiving full medical therapy has completed.
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CLINICAL_TRIALS trial_result · 2010-12-21Clinical Trial Update: Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart Failure [Phase 2]
Phase 2 pharmacokinetic study of oral CK-1827452 in patients with stable heart failure, with results posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-12-09Clinical Trial Update: Effects of Pyruvate in Patients With Cardiogenic Shock and Intra-aortic Balloon Counterpulsation [Phase 2]
Phase 2 trial evaluating pyruvate in patients with cardiogenic shock supported by intra-aortic balloon counterpulsation has completed; resul…
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CLINICAL_TRIALS trial_result · 2010-12-03Clinical Trial Update: Impact of Darbepoetin Alfa on Exercise Tolerance and Left Ventricular Structure in Subjects With Symptomatic Congestive Heart Failure (CHF) and Anemia [NA]
This clinical trial evaluated the effects of darbepoetin alfa on exercise tolerance and left ventricular structure in patients with symptoma…
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FDA approval · 2010-12-03FDA Approved: MILRINONE LACTATE — Original Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved Hikma Pharmaceuticals USA Inc.'s original application for milrinone lactate injection, a generic milrinone, for the short-t…
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CLINICAL_TRIALS trial_result · 2010-12-02Clinical Trial Update: Observational Usage and Efficacy Study of Candesartan in Heart Failure Treatment in France
A completed observational study in France evaluated the usage patterns and efficacy of candesartan for heart failure treatment.
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FDA approval · 2010-11-29FDA Approved: TRANDOLAPRIL — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for the generic drug trandolapril from Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2010-11-24Clinical Trial Update: Chagas Cardiomyopathy Bisoprolol Intervention Study: Charity [Phase 3]
This clinical trial update reports the completion of a Phase 3 study evaluating bisoprolol in patients with Chagas cardiomyopathy and chroni…
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CLINICAL_TRIALS trial_result · 2010-11-24Clinical Trial Update: Identification of the Pericardiophrenic Vein During Cardiac Device Implant Procedures to Prevent Extracardiac Stimulation
Completed clinical trial evaluating identification of the pericardiophrenic vein during cardiac device implant procedures to prevent extraca…
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CLINICAL_TRIALS withdrawal · 2010-11-23Clinical Trial Update: International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia [Phase 3]
An international Phase 3 trial evaluating oral lixivaptan for hypervolemic hyponatremia in heart failure patients has been withdrawn.