Heart Failure
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CLINICAL_TRIALS trial_result · 2011-08-30Clinical Trial Update: Evaluation of Myocardial Improvement in Patients Supported by Ventricular Assist Device Under Optimal Pharmacological Therapy [Phase 4]
Phase 4 clinical trial evaluating myocardial improvement in heart failure patients supported by a ventricular assist device under optimal ph…
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CLINICAL_TRIALS research · 2011-08-30Clinical Trial Update: Group Psychotherapy Among Congestive Heart Failure Patients
This clinical trial update describes a study evaluating group psychotherapy for patients with congestive heart failure. The current status i…
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FDA approval · 2011-08-29FDA Approved: BISOPROLOL FUMARATE — Supplemental Application (TruPharma LLC)
The FDA approved a supplemental application for bisoprolol fumarate by TruPharma LLC, under an ANDA.
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FDA approval · 2011-08-29FDA Approved: BISOPROLOL FUMARATE — Supplemental Application (NorthStar Rx LLC)
FDA approved NorthStar Rx LLC's supplemental application for bisoprolol fumarate, confirming approval of a generic product. The approval per…
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CLINICAL_TRIALS trial_result · 2011-08-18Clinical Trial Update: Right Ventricular Failure in Congenital Heart Defects
A completed clinical trial examining right ventricular failure in congenital heart defects, sponsored by the Competence Network for Congenit…
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CLINICAL_TRIALS trial_result · 2011-08-16Clinical Trial Update: Cardiac Magnetic Resonance Imaging Guided Left Ventricular Lead Placement [Phase 3]
Phase 3 clinical trial evaluating MRI-guided left ventricular lead placement for heart failure; current status is unknown.
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CLINICAL_TRIALS research · 2011-08-11Clinical Trial Update: Resynchronization in Paced Heart Failure Patients With Implantable Cardioverter Defibrillator (ICD) Indication [Phase 4]
Phase 4 trial update on resynchronization therapy in paced heart failure patients with ICD indication; the current status of the study is un…
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CLINICAL_TRIALS other · 2011-08-09Clinical Trial Update: Comparison of Different Locations for Pulse Oximetry Probes in Cardiovascular (CV) Patients With Poor Peripheral Perfusion
This clinical trial update notes termination of a study evaluating different probe locations for pulse oximetry in cardiovascular patients w…
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CLINICAL_TRIALS research · 2011-08-08Clinical Trial Update: Catheter Ablation Versus Medical Treatment of AF in Heart Failure [NA]
This entry notes a clinical trial comparing catheter ablation versus medical treatment for atrial fibrillation in patients with heart failur…
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CLINICAL_TRIALS trial_result · 2011-08-05Clinical Trial Update: Exercise Oscillatory Breathing and Sildenafil in Heart Failure [Phase 2]
Phase 2 trial evaluating the combination of exercise oscillatory breathing and sildenafil in heart failure has completed.
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CLINICAL_TRIALS withdrawal · 2011-08-04Clinical Trial Update: Impact of Clinical, Demographic and Laboratory Variables on Brain Natriuretic Peptide Levels
The trial evaluating factors that influence brain natriuretic peptide levels in patients with sepsis or heart failure has been withdrawn fro…
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FDA approval · 2011-08-02FDA Approved: QUINAPRIL HYDROCHLORIDE/HYDROCHLOROTHIAZIDE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for Quinapril Hydrchloride/Hydrochlorothiazide manufactured by Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2011-07-27Clinical Trial Update: Empowering Elders Through Technology [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial sponsored by the Robert Wood Johnson Foundation evaluated a technology-based intervention to help older…
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CLINICAL_TRIALS trial_result · 2011-07-26Clinical Trial Update: FUSION I Assesses Safety and Tolerability of Two Doses of NATRECOR (Nesiritide) Administered to Patients With Worsening Congestive (Decompensated) Heart Failure Who Are Concurrently Receiving Their Usual Cardiac Medications and Are at High Risk for Hospitalization. [Phase 3]
This clinical trial update reports the completion of a Phase 3 study evaluating the safety and tolerability of two doses of nesiritide (NATR…
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CLINICAL_TRIALS trial_result · 2011-07-26Clinical Trial Update: Does Access to an EHR Patient Portal Influence Chronic Disease Outcomes? [NA]
Completed study evaluating whether access to an electronic health record (EHR) patient portal influences outcomes in chronic diseases. The c…
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FDA approval · 2011-07-26FDA Approved: CHLOROTHIAZIDE SODIUM — Original Application (Sun Pharmaceutical Industries, Inc.)
FDA approved Sun Pharmaceutical Industries' original application for CHLOROTHIAZIDE SODIUM, a thiazide diuretic, for the treatment of hypert…
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CLINICAL_TRIALS trial_result · 2011-07-25Clinical Trial Update: PUFAs and Left Ventricular Function in Heart Failure [Phase 3]
Phase 3 trial evaluating omega-3 polyunsaturated fatty acids on left ventricular function in patients with dilated cardiomyopathy and heart …
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FDA approval · 2011-07-22FDA Approved: CAPTOPRIL — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved a supplemental application for CAPTOPRIL from Hikma Pharmaceuticals USA Inc., indicating additional approval for this generic A…
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CLINICAL_TRIALS trial_result · 2011-07-22Clinical Trial Update: A Pharmacogenomic Study of Candesartan in Heart Failure [Phase 4]
Phase 4 pharmacogenomic study of candesartan in heart failure has completed.
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CLINICAL_TRIALS trial_result · 2011-07-22Clinical Trial Update: The Effects of Carperitide on Short and Long-term Prognosis in Patients With Both Cardiac and Renal Failure [Phase 4]
A Phase 4 clinical trial evaluating the effects of carperitide on short- and long-term prognosis in patients with both heart failure and ren…
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FDA approval · 2011-07-21FDA Approved: PERINDOPRIL ERBUMINE — Supplemental Application (Aurobindo Pharma Limited)
The FDA approved a supplemental application for a generic version of perindopril erbumine from Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2011-07-21Clinical Trial Update: Non-invasive Assessment of Liver Stiffness/Fibrosis by Transient Elastography (Fibroscan) in Patients With Left and/or Right Sided Heart Failure
The study evaluates non-invasive liver stiffness/fibrosis assessment using transient elastography (FibroScan) in patients with left- or righ…
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CLINICAL_TRIALS other · 2011-07-21Clinical Trial Update: Evaluation of Resynchronization Therapy for Heart Failure [Phase 4]
A Phase 4 clinical trial evaluating resynchronization therapy for heart failure (NCT00900549) has been terminated. Sponsor: Montreal Heart I…
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CLINICAL_TRIALS trial_result · 2011-07-21Clinical Trial Update: Matrix Metalloproteinase (MMP) in Heart Failure
This document notes the completion of a clinical trial evaluating matrix metalloproteinases in chronic heart failure.
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients With Heart Failure, and in Healthy Volunteers [Phase 2]
Phase 2 trial evaluating the effects of urotensin-II and soluble epoxide hydrolase inhibitors on skin microvessel tone in heart failure pati…