Heart Failure
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Sign up freeTop drugs studied for this disease
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FDA approval · 2014-11-04FDA Approved: LOSARTAN POTASSIUM — Supplemental Application (Macleods Pharmaceuticals Limited)
The FDA has granted supplemental approval for Losartan Potassium from Macleods Pharmaceuticals Limited. This action approves the supplementa…
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CLINICAL_TRIALS research · 2014-11-04Clinical Trial Update: Effects of Cardiac Sympathetic Blockade in Patients With Chronic Heart Failure
This document provides an update on a clinical trial evaluating cardiac sympathetic blockade in patients with chronic heart failure; the cur…
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FDA approval · 2014-11-03FDA Approved: CAPTOPRIL — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
FDA approved Hikma Pharmaceuticals USA's supplemental application for captopril (CAPTOPRIL), enabling the generic captopril product under th…
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FDA approval · 2014-10-31FDA Approved: LISINOPRIL — Supplemental Application (Solco healthcare U.S., LLC)
The FDA approved a supplemental application for lisinopril from Solco Healthcare U.S., LLC.
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CLINICAL_TRIALS research · 2014-10-30Clinical Trial Update: Robotic Assisted Rehabilitation for Heart Failure Patients and Patients After Cardiac Surgery [NA]
Clinical trial update on robotic-assisted rehabilitation for heart failure patients and patients after cardiac surgery; the study status is …
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CLINICAL_TRIALS trial_result · 2014-10-29Clinical Trial Update: At-Home Automated External Defibrillator (AED) Training Study [Phase 2]
Phase 2 trial update evaluating an at-home automated external defibrillator (AED) training program has completed. The study was sponsored by…
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CLINICAL_TRIALS trial_result · 2014-10-28Clinical Trial Update: Cardiovascular Diseases in HIV-infected Patients HIV-HEART Study: 7.5 Years Follow-up
This is a 7.5-year follow-up update from the HIV-HEART trial evaluating cardiovascular outcomes in HIV-infected patients with coronary heart…
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CLINICAL_TRIALS trial_result · 2014-10-27Clinical Trial Update: Model 4968 CAPTURE EPI® STERIOD-ELUTING BIPOLAR EPICARDIAL PACING LEAD Post-approval Study
Post-approval study evaluating the CAPTURE EPI steroid-eluting bipolar epicardial pacing lead in patients with arrhythmia and heart failure;…
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CLINICAL_TRIALS research · 2014-10-23Clinical Trial Update: Intravascular Ultrasound Evaluation of Renal Nerves in Different Diseases
A clinical trial evaluating renal nerve characteristics using intravascular ultrasound in hypertension and heart failure. The study status i…
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CLINICAL_TRIALS withdrawal · 2014-10-23Clinical Trial Update: Phase I Interaction Study of Istaroxime and Digoxin in Subjects With Stable Heart Failure [Phase 1]
Phase I study examining interaction between istaroxime and digoxin in subjects with stable heart failure has been withdrawn.
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FDA approval · 2014-10-22FDA Approved: SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE — Supplemental Application (Prasco Laboratories)
FDA approved a supplemental application for a generic spironolactone and hydrochlorothiazide combination product from Prasco Laboratories.
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CLINICAL_TRIALS trial_result · 2014-10-22Clinical Trial Update: Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy [Phase 2]
Phase 2 trial completed evaluating prevention of cardiac dysfunction during adjuvant therapy for breast cancer.
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FDA approval · 2014-10-20FDA Approved: BUMETANIDE — Supplemental Application (Sandoz Inc)
FDA approved a supplemental application for bumetanide from Sandoz Inc.
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CLINICAL_TRIALS trial_result · 2014-10-20Clinical Trial Update: Using Allopurinol to Relieve Symptoms in Patients With Heart Failure and High Uric Acid Levels [Phase 2]
Phase 2 trial evaluating allopurinol for symptom relief in patients with heart failure and elevated serum uric acid.
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Assess Measurements of Wireless Cardiac Output Device
A completed clinical trial evaluating measurements from a wireless cardiac output device in patients with heart failure.
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Evia/Entovis HF-T Master Study
The HF-T Master Study evaluating Biotronik's Evia/Entovis CRT device for heart failure indications has completed.
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Beta-Blockers in Heart Failure: Pharmacy-level Intervention Comparison [NA]
This is a clinical trial update reporting results from a completed study comparing pharmacy-level interventions to optimize beta-blocker use…
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CLINICAL_TRIALS trial_result · 2014-10-13Clinical Trial Update: The Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Myocardial Function in Patients Undergoing LVAD Implantation [Phase 2]
A Phase 2 trial evaluated intramyocardial injection of mesenchymal precursor cells in patients undergoing LVAD implantation to assess change…
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: Optimal Cardiac Resynchronization Therapy Pacing Rate [EARLY_Phase 1]
A Phase 1 trial evaluating the optimal pacing rate for cardiac resynchronization therapy in heart failure has completed.
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CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: MIRACLE EF Clinical Study [NA]
The MIRACLE EF clinical trial conducted by Medtronic was terminated, and its results were posted on 2014-10-06.
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: A Multi-center, Placebo-controlled Study to Evaluate the Safety of GSK716155 and Its Effects on Myocardial Metabolism, Myocardial Function, and Exercise Capacity in Patients With NYHA Class II/III Congestive Heart Failure [Phase 2]
A Phase 2 multi-center, placebo-controlled trial evaluated the safety, myocardial metabolism, function, and exercise capacity effects of GSK…
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: Is There a Benefit to Optimize Heart Failure (HF) Treatment in Aged Over 80 Year's Old Patients? [Phase 3]
A Phase 3 trial evaluating optimization of heart failure treatment in patients aged over 80 has completed; no results are detailed in the sn…
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CLINICAL_TRIALS trial_result · 2014-09-30Clinical Trial Update: Heart Rate Reduction in Heart Failure [Phase 3]
A Phase 3 trial evaluating heart rate reduction in heart failure has completed, with results posted on 2014-09-30.
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CLINICAL_TRIALS other · 2014-09-30Clinical Trial Update: Relative Bioavailability Study With Enalapril in Healthy Volunteers [Phase 1]
A Phase 1 relative bioavailability study of enalapril in healthy volunteers, sponsored by Ethicare GmbH, related to heart failure, is docume…
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CLINICAL_TRIALS trial_result · 2014-09-29Clinical Trial Update: PRospective Evaluation of Electrocardiographic Voltage Changes and Six Minute Walk Test for Predicting Readmissions in Heart Failure (PREEMT-HF Study)
A completed clinical trial evaluating electrocardiographic voltage changes and the six-minute walk test to predict readmissions in heart fai…