Heart Failure
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CLINICAL_TRIALS trial_result · 2015-10-20Clinical Trial Update: A Comparison of Two Techniques for Choosing the Best Place to Put a Pacing Lead for Cardiac Resynchronisation Therapy
This completed clinical trial compared two techniques for selecting the best site to place a pacing lead for cardiac resynchronization thera…
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CLINICAL_TRIALS trial_result · 2015-10-19Clinical Trial Update: Outlook Quality of Life Intervention Study [NA]
A VA-sponsored clinical trial titled 'Outlook Quality of Life Intervention Study' has completed enrollment. Results have been posted (2015-1…
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CLINICAL_TRIALS research · 2015-10-19Clinical Trial Update: Dental Anesthesia in Heart Failure Patients [NA]
This clinical trial update concerns dental anesthesia in heart failure patients, sponsored by the University of Sao Paulo General Hospital, …
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CLINICAL_TRIALS trial_result · 2015-10-16Clinical Trial Update: Veterans Affairs Lowering Readmission in Heart Failure [NA]
A Veterans Affairs trial aimed at reducing hospital readmissions for heart failure has completed, with results posted in 2015.
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CLINICAL_TRIALS withdrawal · 2015-10-15Clinical Trial Update: A Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of Bendavia™ (MTP-131) in Patients With Heart Failure [Phase 1]
A Phase 1 multiple ascending dose trial of Bendavia (MTP-131) in heart failure has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: A Pharmacokinetic and Pharmacodynamic Study of Omecamtiv Mecarbil in Healthy Volunteers [Phase 1]
Phase 1 pharmacokinetic and pharmacodynamic study of Omecamtiv Mecarbil in healthy volunteers conducted by Cytokinetics, related to heart fa…
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: Improvement of Patients With Chronic Heart Failure Using NT-proBNP [Phase 4]
Phase 4 clinical trial assessing improvement in congestive heart failure patients using the NT-proBNP biomarker.
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: Precision of IMED-4 Lung Fluid Measurements
A completed clinical trial evaluating the precision of IMED-4 lung fluid measurements in patients with dyspnea related to acute heart failur…
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: Fluid Status of Outpatients With Dyspnea
This clinical trial update reports the completion status of a study evaluating fluid status in outpatients with dyspnea. The study relates t…
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CLINICAL_TRIALS trial_result · 2015-10-14Clinical Trial Update: Cardiac Rhythm Monitoring After Acute Decompensation for Heart Failure
This document reports the completion of a clinical trial evaluating cardiac rhythm monitoring after acute decompensation in heart failure.
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CLINICAL_TRIALS withdrawal · 2015-10-14Clinical Trial Update: Trial to Determine Imaging Parameters of LMI1195 in Heart Failure Patients at Low and High Risk of Defibrillator Firing [Phase 2]
A Phase 2 trial evaluating imaging parameters of LMI1195 in heart failure patients at low and high risk of defibrillator firing has been wit…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Study of Safety, Tolerability and Pharmacokinetics of Serelaxin in Japanese Acute Heart Failure (AHF) Patients [Phase 2]
This update reports Phase 2 results on safety, tolerability, and pharmacokinetics of serelaxin in Japanese patients with acute heart failure…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Improving Heart Failure Care in Minority Communities [NA]
This clinical trial update notes the completion of a study aimed at improving heart failure care in minority communities.
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CLINICAL_TRIALS research · 2015-10-12Clinical Trial Update: Non-invasive Blood Pressure and Cardiac Output Measurement by Using Applanation Tonometry
This entry provides an update on a clinical trial evaluating non-invasive blood pressure and cardiac output measurement using applanation to…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Monitoring of Fluid Status in Heart Failure Patients by Intrathoracic Impedance Measurement in Japan (J-HomeCARE II) [Phase 4]
A Phase 4 study (J-HomeCARE II) evaluating intrathoracic impedance monitoring to manage fluid status in heart failure patients in Japan has …
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: The Effect of Liraglutide on Left Ventricular Function in Chronic Heart Failure Patients With and Without Type 2 Diabetes Mellitus [NA]
A completed clinical trial studied the effect of liraglutide on left ventricular function in chronic heart failure patients, with and withou…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment [NA]
Clinical trial update for aquapheresis versus IV diuretics in heart failure; study terminated with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-09Clinical Trial Update: Safety and Efficacy of Direct Blood Volume Measurement in the Treatment of Heart Failure [Phase 4]
A Phase 4 trial evaluating direct blood volume measurement for the treatment of heart failure was terminated.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: A Phase IIb Study to Investigate the Efficacy and Tolerability of Cinaciguat (150 µg/h, 100 µg/h, 50 µg/h) Given Intravenously to Subjects With Acute Decompensated Chronic Congestive Heart Failure (ADHF) [Phase 2]
A Phase IIb study evaluating intravenous Cinaciguat in patients with acute decompensated heart failure was terminated.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: Acute and Cronic Evaluation of AV/PV and VV Delay IEGM Based Optimisation Algorithm-QuickSept Study
A completed clinical trial evaluating AV/PV and VV delay optimization using the IEGM-based QuickSept algorithm in heart failure patients.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: 12-Week-Combined Physical Training In Heart Failure Patients [NA]
This entry reports the completion of a clinical trial evaluating 12-week combined physical training in heart failure patients.
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: BAY58-2667 Dose Finding Trial Investigating Fixed Doses in Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF) [Phase 2]
A Phase 2 dose-finding trial of BAY58-2667 in patients with acute heart failure has been terminated. The study investigated fixed dosing in …
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: Beta-2 Polymorphisms and Beta Receptor Selectivity [NA]
This clinical trial update notes a completed study exploring how beta-2 receptor polymorphisms influence beta receptor selectivity in heart …
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Patient-Centered Advance Care Planning [Phase 3]
A Phase 3 clinical trial on patient-centered advance care planning in patients with heart failure or renal failure has completed.
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FDA approval · 2015-10-02FDA Approved: COREG CR — Supplemental Application (Waylis Therapeutics LLC)
FDA approved a supplemental application for COREG CR (carvedilol phosphate) from Waylis Therapeutics LLC, approving the controlled-release f…