Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Attain Performa(TM) Quadripolar Lead Study [NA]
The Attain Performa Quadripolar Lead study sponsored by Medtronic Cardiac Rhythm and Heart Failure has completed and posted its results (201…
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FDA approval · 2016-12-01FDA Approved: LANOXIN — Supplemental Application (Advanz Pharma (US) Corp.)
The FDA approved a supplemental application for LANOXIN (digoxin) submitted by Advanz Pharma US Corp.
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FDA approval · 2016-12-01FDA Approved: DIGOXIN — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for Digoxin from Hikma Pharmaceuticals USA Inc. The action reflects approved product changes und…
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CLINICAL_TRIALS trial_result · 2016-12-01Clinical Trial Update: Frailty Score Assessment for Elderly Patients Undergoing Cardiac Resynchronization Therapy
A completed clinical trial evaluating frailty score assessment in elderly patients undergoing Cardiac Resynchronization Therapy for heart fa…
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CLINICAL_TRIALS trial_result · 2016-11-25Clinical Trial Update: Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure [Phase 3]
Phase 3 trial evaluating aliskiren alone and in combination with enalapril for chronic heart failure; results were posted after completion t…
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FDA approval · 2016-11-25FDA Approved: METOPROLOL SUCCINATE — Original Application (Actavis Pharma, Inc.)
FDA approved the original application for metoprolol succinate, establishing a generic sustained-release formulation from Actavis Pharma, In…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: The Effect of Glucose-Insulin-Potassium Infusion in Patients Undergoing Cardiac Surgery [NA]
Clinical trial evaluating the effect of glucose-insulin-potassium infusion in patients undergoing cardiac surgery has completed.
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CLINICAL_TRIALS research · 2016-11-22Clinical Trial Update: Inflammatory Cardiomyopathy Baseline Cohort (SFB/TR19)
This clinical trial registry entry for the Inflammatory Cardiomyopathy Baseline Cohort (SFB/TR19) indicates that the study sponsored by Univ…
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CLINICAL_TRIALS trial_result · 2016-11-21Clinical Trial Update: Targeting Sympathetic Overactivity in Heart Failure Patients With Statins [NA]
The trial evaluating the effect of statins on sympathetic overactivity in heart failure patients has completed, with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Efficacy and Safety of Valsartan Versus Placebo on Exercise Tolerance in Patients With Heart Failure [Phase 4]
This Phase 4 trial evaluates the efficacy and safety of valsartan versus placebo on exercise tolerance in patients with diastolic dysfunctio…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Vitamin D Supplementation for Treatment of Heart Failure [Phase 4]
Phase 4 clinical trial evaluating vitamin D supplementation for heart failure has been terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: A Dose-Defining Study of CXL-1020 in Patients With Systolic Heart Failure [Phase 2]
Phase 2 dose-defining study of CXL-1020 in patients with systolic heart failure has completed, reporting phase 2 results.
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Insulin Effects on Cardiac Function in Patients With Diabetes Mellitus [Phase 4]
Phase 4 clinical trial evaluating the effects of insulin on cardiac function in patients with diabetes mellitus has completed.
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CLINICAL_TRIALS trial_result · 2016-11-09Clinical Trial Update: Safety of Repeat Doses of IV Serelaxin in Subjects With Chronic Heart Failure [Phase 2]
Phase 2 trial evaluating the safety of repeat intravenous dosing of serelaxin in adults with chronic heart failure; results posted.
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CLINICAL_TRIALS research · 2016-11-09Clinical Trial Update: The Effect of CRT on the Hypercapnic Ventilatory Response
Clinical trial NCT02203383 evaluating the effect of cardiac resynchronization therapy on the hypercapnic ventilatory response has been suspe…
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CLINICAL_TRIALS trial_result · 2016-11-09Clinical Trial Update: Validation of the ApneaScan Algorithm in Sleep Disordered Breathing
Clinical trial update validating the ApneaScan algorithm for sleep-disordered breathing. Heart failure is among the conditions studied.
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Pharmacodynamic and Pharmacokinetic Study of BiDil Extended-release Capsules and Commercial BiDil Tablets [Phase 1]
Phase 1 pharmacodynamic and pharmacokinetic study comparing extended-release BiDil capsules with commercial BiDiL tablets in heart failure p…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure [Phase 2]
This update reports that a Phase 2 trial evaluating carperitide in congestive heart failure has completed. The snippet does not provide tria…
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CLINICAL_TRIALS withdrawal · 2016-11-04Clinical Trial Update: The Role of Adrenomedullin on the Outcome of Severe Heart Failure: a Clinical Randomized Study [NA]
A randomized clinical trial evaluating the role of adrenomedullin in outcome for severe heart failure was withdrawn from ClinicalTrials.gov.
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FDA label_change · 2016-11-02FDA Approved: DIGOXIN — Supplemental Application (Sandoz Inc)
FDA approved a supplemental application for digoxin from Sandoz Inc, resulting in a label change for the generic heart medication.
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CLINICAL_TRIALS research · 2016-11-01Clinical Trial Update: Strain Echo in Acute Heart Failure
An update on a clinical study evaluating strain echocardiography in acute heart failure, sponsored by Wayne State University.
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Evaluation of Vepoloxamer in Chronic Heart Failure [Phase 2]
A Phase 2 trial of Vepoloxamer for chronic heart failure was terminated before completion.
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Clinical Study Of Eplerenone In Japanese Patients With Chronic Heart Failure [Phase 3]
Phase 3 trial of eplerenone in Japanese patients with chronic heart failure has completed; results posted in 2016.
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FDA approval · 2016-10-27FDA Approved: ACETAZOLAMIDE — Original Application (Chartwell RX, LLC)
FDA approved an original application for acetazolamide from Chartwell RX, LLC.
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CLINICAL_TRIALS trial_result · 2016-10-27Clinical Trial Update: Mitral Valve Reconstruction in Chronic Heart Failure (CHF): Identification of Predictors for a Successful Therapy [Phase 2]
Phase 2 trial evaluating mitral valve reconstruction in chronic heart failure was terminated. The study aimed to identify predictors of a su…