Heart Failure
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-10-16Clinical Trial Update: Pilot Study for First Clinical Use of sc2Wear Furosemide Combination Product [Phase 2]
A Phase 2 pilot study evaluating the first clinical use of the sc2Wear Furosemide Combination Product for heart failure has completed.
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Mitral Loop Cerclage(MLC) for Reducing Functional Mitral Regurgitation [NA]
This document provides an update on a completed clinical trial evaluating Mitral Loop Cerclage (MLC) for reducing functional mitral regurgit…
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CLINICAL_TRIALS trial_result · 2017-10-12Clinical Trial Update: New Heart Failure Biomarkers in Early Stage Chronic Kidney Disease-Mineral and Bone Disorder
A completed clinical trial evaluating novel heart failure biomarkers in patients with early-stage chronic kidney disease and mineral and bon…
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CLINICAL_TRIALS trial_result · 2017-10-11Clinical Trial Update: The Role of CVP and EF in Patients With Cardio-renal Syndromes
A completed clinical trial evaluated the role of central venous pressure (CVP) and ejection fraction (EF) in patients with cardiorenal syndr…
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: Inhaled Nitric Oxide and Inhaled Prostacyclin After Cardiac Surgery for Heart Transplant or LVAD Placement [Phase 4]
Phase 4 clinical trial update assessing inhaled nitric oxide and inhaled prostacyclin after cardiac surgery for heart transplant or LVAD pla…
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: Evaluating the Safety and Efficacy of Qishen Granules Among Patients With Chronic Heart Failure [Phase 2]
A Phase 2 clinical trial evaluating the safety and efficacy of Qishen Granules in patients with chronic heart failure.
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CLINICAL_TRIALS trial_result · 2017-10-04Clinical Trial Update: The Impact of Zinc Supplementation on Left Ventricular Function in Nonischemic Cardiomyopathy [Phase 1]
A Phase 1 trial evaluating zinc supplementation for left ventricular function in nonischemic cardiomyopathy has completed, with results post…
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CLINICAL_TRIALS trial_result · 2017-10-03Clinical Trial Update: Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEF [Phase 2]
Phase 2 trial assessing pharmacokinetics and pharmacodynamics of inorganic nitrate and its impact on exercise in heart failure with preserve…
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: The Use of Intranasal Fentanyl for the Treatment of Incident Dyspnea in Congestive Heart Failure: A Prospective Trial [Phase 2]
Phase 2 trial investigating intranasal fentanyl for incident dyspnea in congestive heart failure has completed.
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FDA approval · 2017-09-22FDA Approved: INDAPAMIDE — Supplemental Application (ANI Pharmaceuticals, Inc.)
FDA approved a supplemental application for Indapamide (ANI Pharmaceuticals), updating its regulatory approval.
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CLINICAL_TRIALS trial_result · 2017-09-19Clinical Trial Update: Donor Simvastatin Treatment in Organ Transplantation [Phase 2, Phase 3]
Clinical trial update on donor simvastatin treatment in organ transplantation across Phase 2 and Phase 3, completed; conditions listed inclu…
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FDA label_change · 2017-09-14FDA Approved: COREG — Supplemental Application (Waylis Therapeutics LLC)
FDA approved a supplemental application for COREG (carvedilol) submitted by Waylis Therapeutics LLC, typically involving a label change or n…
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FDA label_change · 2017-09-14FDA Approved: COREG CR — Supplemental Application (Waylis Therapeutics LLC)
FDA approved a supplemental application for COREG CR (carvedilol phosphate) from Waylis Therapeutics LLC, detailing changes related to the C…
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CLINICAL_TRIALS withdrawal · 2017-09-12Clinical Trial Update: Phosphodiesterase Type 5 Inhibition With Tadalafil Changes Outcomes in Heart Failure: Extent of Renal Damage [Phase 3]
A Phase 3 trial evaluating tadalafil for heart failure and pulmonary hypertension has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-09-07Clinical Trial Update: A Study to Evaluate the Effects of 4 Weeks Treatment With Subcutaneous Elamipretide on Left Ventricular Function in Subjects With Stable Heart Failure With Preserved Ejection Fraction [Phase 2]
Phase 2 trial evaluating subcutaneous Elamipretide for 4 weeks in stable heart failure with preserved ejection fraction has completed.
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: Evaluation of Automatic Threshold Algorithms [NA]
This clinical trial update reports results from evaluating automatic threshold algorithms in the context of heart failure, with results post…
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure [Phase 2]
An open-label Phase 2 study evaluating Perhexiline in patients with hypertrophic cardiomyopathy and moderate-to-severe heart failure was ter…
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Study of Qiliqiangxin Capsule to Treat Dilated Cardiomyopathy [Phase 4]
Phase 4 clinical trial of Qiliqiangxin Capsule assessing treatment of dilated cardiomyopathy and heart failure has been completed.
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: AAV1-CMV-Serca2a GENe Therapy Trial in Heart Failure [Phase 2]
A phase 2 trial evaluating AAV1-CMV-SERCA2a gene therapy for heart failure, including congestive heart failure and ischemic or non-ischemic …
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CLINICAL_TRIALS trial_result · 2017-08-25Clinical Trial Update: Usefulness of Lung Ultrasound in Ambulatory Management of Patients With Chronic Heart Failure [Phase 3]
A Phase 3 trial evaluating the usefulness of lung ultrasound in ambulatory management of patients with chronic heart failure has been termin…
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CLINICAL_TRIALS trial_result · 2017-08-24Clinical Trial Update: Effect of Remote Ischemic Conditioning in Patients With Chronic Ischemic Heart Failure [NA]
A completed clinical trial investigates the effect of remote ischemic conditioning in patients with chronic ischemic heart failure. This upd…
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CLINICAL_TRIALS research · 2017-08-23Clinical Trial Update: CRT In Narrow QRS Heart Failure: Mechanistic Insights From Cardiac MRI And Electroanatomical Mapping [NA]
This clinical trial update investigates the mechanistic aspects of cardiac resynchronization therapy (CRT) in patients with narrow QRS heart…
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CLINICAL_TRIALS trial_result · 2017-08-23Clinical Trial Update: Invasive Monitoring of Pulmonary Artery Pressure (PAP) Among Dialysis Treated Patients
This clinical trial update reports on invasive monitoring of pulmonary artery pressure in dialysis-treated patients with end-stage renal dis…
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CLINICAL_TRIALS withdrawal · 2017-08-23Clinical Trial Update: High Intensity Interval Training in Heart Failure [NA]
A clinical trial investigating high-intensity interval training for heart failure has been withdrawn.
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CLINICAL_TRIALS research · 2017-08-22Clinical Trial Update: Transitional Palliative Care in End-stage Heart Failure [NA]
A completed clinical trial evaluating transitional palliative care for patients with end-stage heart disease and heart failure. The update d…